Abstract: A gasket suitable for a syringe stopping with vacuum is provided. The gasket is compatible with sliding property within the sleeve and water-tightness of the syringe barrel after exiting the sleeve. The gasket includes a gasket body made of a liquid-resistant hard plastic having a tip surface contacting medicinal solution and a concave groove formed on a side surface facing an inner peripheral surface of a syringe barrel and formed continuously to the tip surface contacting medicinal solution; and a sliding contact ring made of an elastic material fitted in the concave groove. Then, an outer diameter D1 of a peripheral end of a tip portion including the tip surface contacting medicinal solution of the gasket body is set to be larger than the outer diameter D4 of the sliding contact ring.

Abstract: A high-slidability syringe has high safety and sealability over a long period of time. The syringe includes a gasket having a lower sliding resistance to a syringe barrel. The syringe includes: a syringe barrel; a gasket adapted to be press-fitted in the syringe barrel and used in a sliding manner in the syringe barrel; and a piston rod with the gasket attached to a front end thereof. The gasket includes: a gasket main body that is formed of a rigid plastic having resistance to a drug solution to be loaded into the syringe barrel and has a recessed groove formed in a sliding contact surface thereof adapted to slidably contact an inner circumferential surface of the syringe barrel; and a sliding contact ring that is fitted in the recessed groove.

Abstract: A syringe is to be obtained by using PTFE for a gasket main body that makes a direct contact with an injection solution and using a slidable silicone rubber at a portion that does not make contact with the injection solution. A syringe A includes a syringe barrel 1, a gasket 10 press-fitted within the syringe barrel 1, and a plunger rod 5 mounted in the gasket 10. In the gasket 10, a concaved groove 18 is formed over the whole circumference of a slide-contact surface 11 of a main body portion 26 that is formed of a rigid plastic having a drug solution-resistant property against a drug solution 30 to be loaded in the syringe barrel 1 and that is configured to slidingly contact an inner circumferential surface 2 of the syringe barrel 1.

Abstract: A method to make a PTFE skived film capable of exhibiting, with a single layer, sliding properties, barrier properties with regard to a liquid contact surface, and excellent tear resistance during injection molding. This skived film is obtained by cutting a polytetrafluoroethylene block or a modified polytetrafluoroethylene block subjected to a thermal fusion treatment under reduced pressure or subjected to a pressurized thermal fusion treatment after being subjected to fusion under reduced pressure.

Abstract: Provided is a PTFE skived film capable of exhibiting, with a single layer, sliding properties, barrier properties with regard to a liquid contact surface, and excellent tear resistance during injection molding. This skived film is characterized by being obtained by cutting a polytetrafluoroethylene block or a modified polytetrafluoroethylene block subjected to a thermal fusion treatment under reduced pressure or subjected to a pressurized thermal fusion treatment after being subjected to fusion under reduced pressure.

Abstract: A metal mold capable of preventing a nonuniform wall thickness from occurring in a cylindrical formed product, wherein a gate (8) for filling molding material is formed in alignment with the center axis (CL) of a tubular mold cavity (4) so that metered resin can be injected and filled from the tip side of a core (5) into the mold cavity, whereby since the metered molding material injected from the gate into the mold cavity uniformly flows around the core, a force is uniformly applied to the side face of the core through all the periphery thereof to prevent the core from falling in one direction and to always position the core at the center of the mold cavity, the molded formed product cannot cause the nonuniform wall thickness.