Abstract: A method is provided for localizing an internal bleeding site whereby a protein or other factor involved in the clotting process is complexed to an imaging agent and injected into a patient believed to be at risk of internal bleeding. A clot in the patient will naturally accumulate a certain concentration of the injected complex, and within a short period of time the concentration becomes sufficient to be detected by an imaging apparatus. The imaging contrast agent may, for example, be an MRI contrast agent, a CT contrast agent, a PET agent, or a fluorescent substance.
Type:
Application
Filed:
January 5, 2009
Publication date:
October 29, 2009
Applicant:
COLD SPRING DIAGNOSTICS, INC.
Inventors:
Seth Karp, Evan Garfein, John V. Frangioni, Shunsuke Onishi
Abstract: The present invention relates to medical diagnostic techniques and more particularly to compositions and methods for locating an internal bleeding site in a subject.
Abstract: The present invention relates to medical diagnostic techniques and more particularly to compositions and methods for locating an internal bleeding site in a subject.