Abstract: The present invention relates to transgenic mice in which the biological function of at least one cell cycle regulatory proteins of the INK4 family is altered.
Type:
Grant
Filed:
April 4, 1996
Date of Patent:
July 6, 1999
Assignees:
Cold Spring Habor Labortary, Albert Einstein College of Medicine of Yeshiva University
Inventors:
David H. Beach, Manuel Serrano, Ronald A. DePinho