Patents Assigned to Cold Spring Harbor Labs.,
  • Method of increasing fruit size in a plant
    Patent number: 6229068
    Abstract: The present invention provides a non-naturally occurring seed plant that is characterized by producing seeds of increased size due to ectopic expression of a nucleic acid molecule encoding an AGL8-related gene product. The AGL8-related gene product can have, for example, substantially the amino acid sequence of an AGL8 ortholog such as Arabidopsis AGL8 (SEQ ID NO:2). The present invention further provides a non-naturally occurring seed plant that is characterized by producing fruit of increased size due to ectopic expression of a nucleic acid molecule encoding an AGL8-family gene product. The AGL8-family gene product can have substantially the amino acid sequence of an AGL8 ortholog, for example, the amino acid sequence of Arabidopsis AGL8 (SEQ ID NO:2). Related methods and kits also are provided.
    Type: Grant
    Filed: June 26, 1998
    Date of Patent: May 8, 2001
    Assignees: Cold Spring Harbor Labs.,, The Regents of the University of California
    Inventors: Martin F. Yanofsky, Robert Martienssen, Cristina Ferrandiz, Qing Gu
  • Method of screening for antimitotic compounds using the CDC25 tyrosine phosphatase
    Patent number: 5294538
    Abstract: A method of identifying compounds or molecules which alter (enhance or inhibit) stimulation of kinase activity of pre-MPF and, thus, alter (enhance or inhibit) activation of MPF and entry into mitosis. The present method thus makes it possible to identify compounds or molecules which can be administered to regulate the cell cycle; such compounds are also the subject of this invention.
    Type: Grant
    Filed: May 5, 1992
    Date of Patent: March 15, 1994
    Assignee: Cold Spring Harbor Labs.
    Inventor: David H. Beach