Patents Assigned to École Nationale Supérieure de Chimie
-
Publication number: 20240109875Abstract: A novel method for synthesizing NCA compounds. Also, a new use of a peptide coupling agent. The method makes it possible to obtain NCA compounds from ?-amino-acids, under mild and non-racemic reaction conditions, and in the absence of constraining reagents of use, such as phosgene, which may lead to the formation of undesirable by-products.Type: ApplicationFiled: December 21, 2021Publication date: April 4, 2024Applicants: ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER (ENSCM), UNIVERSITE DE MONTPELLIER (UM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Guillaume LACONDE, Jean MARTINEZ, Muriel AMBLARD-CAUSSIL
-
Patent number: 11946909Abstract: The present invention relates to an asymmetric flow field-flow fractionation device (1) configured to separate a sample (8) of particles (12) dispersed in a liquid mobile phase (11), the device including a fractionation microchannel (2) comprising a sample inlet, a sample outlet, an auxiliary microchannel (3) comprising an auxiliary outlet, a semipermeable membrane (10) separating the fractionation microchannel (2) and the auxiliary microchannel (3), said membrane being permeable to liquid and being configured to maintain the particles (12) in said fractionation microchannel (2), the fractionation microchannel (2) being superimposed on the auxiliary microchannel (3), wherein the device (1) comprises two layers (19), each layer being with a microfabricated recess (14) which thickness (t) is less than 100IJm, the membrane (10) being mechanically held in between the two layers (19), the recesses (14) respectively defining the fractionation microchannel (2) and the auxiliary microchannel (3) on each side of the mType: GrantFiled: February 21, 2019Date of Patent: April 2, 2024Assignees: Assistance Publique-Hopitaux de Paris, Centre National de la Recherche Scientifique (CNRS), Institut National de le Recherche Scientifique (CNRS), UNIVERSITÉ PARIS CITÉ, Ecole Nationale Superieure de Chimie de ParisInventors: Hugo Salmon, Rabah Gahoual, Nathalie Mignet, Pascal Houze
-
Patent number: 11919816Abstract: A filter including a porous support defining one or more channels therethrough, and a porous ceramic membrane layer on a surface of the porous support defining at least one of the one or more channels. The ceramic membrane layer includes an inorganic ceramic composition having the formula SiMpxpCyNzOmHn, where each Mp present is independently selected from a p-block element or a d-block element; p is an integer from 1 to 5; for each Mp present, xp is independently from about 0 to about 60; y is from about 0 to about 60; z is from about 0 to about 60; m is from about 0 to about 40; and n is zero or nonzero. At least one of y and z is nonzero when p is zero, and p is nonzero when y and z are both zero.Type: GrantFiled: May 26, 2022Date of Patent: March 5, 2024Assignees: Saudi Arabian Oil Company, Ecole Nationale Supérieure de Chimie de MontpelliInventors: Subhi Mohammed Hassan Al-Jeshi, Aziz Cherifi, David Cornu, Sophie Cerneaux
-
Patent number: 11912645Abstract: The invention is based on the discovery of a new bacterial compound with analgesic properties which could be used as a new tool for the treatment of pain disorders such as visceral pain. Studying the mechanisms implicated in analgesic properties of the probiotic Escherichia coli strain Nissle 1917 (EcN), inventors characterized, the amino fatty acids produced by EcN, which display the Ecn analgesic properties. One of these compounds inhibits the hypersensitivity to colorectal distension induced by capsaicin, which is a very powerful nociceptive compound and acts via the GABA B receptor. Furthermore, inventors demonstrate that this compound is able to cross the cellular epithelial barrier (such as the intestinal epithelium). Thus, the invention relates to a lipopetide compound, derived from gamma-aminobutyric acid. The invention also relates to a lipopeptide compound according to the invention for the treatment of treating pain disorder, such as somatic pain and visceral pain.Type: GrantFiled: April 27, 2018Date of Patent: February 27, 2024Assignees: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS—, ECOLE NATIONALE VETERINAIRE DE TOULOUSE, UNIVERSITE PAUL SABATIER TOULOUSE III, INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT, UNIVERSITE DE MONTPELLIER, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIERInventors: Nicolas Cenac, Justine Bertrand-Michel, Teresa Perez-Berezo, Thierry Durand, Jean-Marie Galano, Julien Pujo, Eric Oswald, Patricia Martin, Pauline Le Faouder, Alexandre Guy
-
Publication number: 20240018674Abstract: The invention relates to the use of a ternary alloy having the formula SixTiyNiz, wherein x, y and z are natural numbers, for use in electrolysis and photoelectrolysis, in particular photo-oxidation of water. One aspect of the invention relates to a method for the manufacture of an electrode, the method comprising a step of heating a carrier comprising a surface having a layer of silicon on which a layer of TiO2 is disposed, the layer of TiO2 being covered with a layer of NiO; the heating step being carried out at a temperature above 1,000° C., and preferably between 1,150° C. and 1,250° C. The invention also relates to an electrode comprising a carrier, said electrode having either: an outer surface on which particles of a ternary alloy having the formula SixTiyNiz are positioned, wherein x, y and z are natural numbers, and wherein the particles form protrusions; or an outer surface consisting of a layer of said alloy, the layer comprising protrusions.Type: ApplicationFiled: November 29, 2021Publication date: January 18, 2024Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES, UNIVERSITE D'AIXMARSEILLE, UNIVERSITE DE RENNES, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE RENNESInventors: Maxime DUFOND, Jean Manuel DECAMS, Lionel SANTINACCI, Gabriel LOGET
-
Publication number: 20230397490Abstract: An active light-emitting layer composition including a thermally activated delayed fluorescence (TADF) molecule with TADF properties as a host material and a luminescent molecule with circularly polarized (CP) properties as a dopant. Also, a light-emitting device, such as an organic light-emitting diodes (OLED), including the active light-emitting layer made of this composition.Type: ApplicationFiled: October 29, 2021Publication date: December 7, 2023Applicants: UNIVERSITE DE RENNES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS -, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE RENNES, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Ludovic FAVEREAU, Jeanne CRASSOUS, Sitthichok KASEMTHAVEECHOK, Kais DHBAIBI, Grégory PIETERS, Benoît RACINE, Etienne QUESNEL
-
Patent number: 11746060Abstract: A method for manufacturing a part made of composite material includes forming a ceramic matrix phase in pores of a fibrous preform by pyrolysis of a cross-linked copolymer ceramic precursor, the cross-linked copolymer including a first precursor macromolecular chain of a first ceramic having free carbon, and a second precursor macromolecular chain of a second ceramic having free silicon, the first macromolecular chain being bonded to the second macromolecular chain by cross-linking bridges including a bonding structure of formula *1—X—*2; in this formula, X designates boron or aluminium, -*1 designates the bond to the first macromolecular chain and -*2 the bond to the second macromolecular chain.Type: GrantFiled: June 2, 2021Date of Patent: September 5, 2023Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SAFRAN CERAMICS, UNIVERSITE DE BORDEAUX, UNIVERSITE DE MONTPELLIER, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIERInventors: Marion France Hélène Schmidt, Samuel Jean-Charles Bernard, Nicolas Eberling-Fux
-
Patent number: 11746065Abstract: A method for manufacturing a part made of composite material in which an adhesion promoter is grafted to a coating present on the fibre surface as well as to a ceramic precursor resin. Afterwards, a ceramic matrix phase is formed in the porosity of the fibre preform by pyrolysis of the polymerised resin.Type: GrantFiled: June 2, 2021Date of Patent: September 5, 2023Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SAFRAN CERAMICS, UNIVERSITE DE BORDEAUX, UNIVERSITE DE MONTPELLIER, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIERInventors: Nicolas Eberling-Fux, Marion France Hélène Schmidt, Samuel Jean-Charles Bernard
-
Patent number: 11723956Abstract: The present invention concerns a thermosensitive polymeric hydrogel comprising at least one thermosensitive copolymer, one aqueous solution, and a mucoadhesive excipient, wherein said thermosensitive polymeric hydrogel further comprises at least one immunostimulatory adjuvant and/or at least one cytokine and/or at least one chemokine and/or atleast one heat shockprotein. Another object of the invention is a thermosensitive polymeric hydrogel according to the invention for use in the treatment of tumors or metastasis in a subject having a cancer, preferably a metastatic cancer.Type: GrantFiled: August 31, 2017Date of Patent: August 15, 2023Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Université de Paris, Assistance Publique—Hopitaux de Paris, Ecole Nationale Superieure de Chimie de Paris, Universite de Versailles—St. Quentin en YvelinesInventors: Robert Malafosse, Nathalie Mignet, Vincent Boudy, Johanne Seguin, Kathia Lemdani, Claude Capron
-
Publication number: 20230255105Abstract: The present invention relates to compounds simultaneously having thermally activated delayed fluorescence (TADF), circularly polarised luminescence (CPL) and aggregation-induced emission enhancement (AIEE) properties. The invention also relates to the use of such compounds as a photocatalyst or as a dopant, in particular in the emitting layers of light-emitting diodes (OLEDs), as well as light-emitting devices or light-emitting diodes (OLEDs) comprising such compounds.Type: ApplicationFiled: July 9, 2021Publication date: August 10, 2023Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ PARIS-SACLAY, UNIVERSITÉ DE RENNES 1, ECOLE NATIONALE SUPÉRIEURE DE CHIMIE DE RENNES, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE RENNESInventors: Grégory Pieters, Ludovic Favereau, Laurelie Poulard, Max Coehlo, Lucas Frederic, Sitthichok Kasemthaveechok, Jeanne Crassous
-
Patent number: 11673912Abstract: A continuous, solvent-free and non-enzymatic method for synthesizing a compound of formula (I): Ra-POLYPEP-Rc (I) wherein: POLYPEP is a poly-amino acid compound, Ra and Rc are as specified, the method including the steps of: a) feeding an extrusion reactor with (1) a compound of formula (II) Ra-PEPNt-Rg (II) wherein; PEPNt is a mono- or a poly-amino acid compound, Ra and Rg are as specified, and (2) a compound of formula (III) H-PEPCt-Rc (III) wherein: PEPCt is a mono- or a poly-amino acid compound, and Rc is as defined in the absence of any solvent, so that the compound of formula (II) and the compound of formula (III) react together for generating a compound of formula (I), and b) collecting the compound of formula (I) from the extrusion reactor.Type: GrantFiled: February 12, 2019Date of Patent: June 13, 2023Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE MONTPELLIER, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER, ECOLE DES MINES D'ALES, ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELSInventors: Yves Yeboue, Benjamin Gallard, Nicolas Le Moigne, Frédéric Lamaty, Jean Martinez, Thomas-Xavier Metro
-
Patent number: 11634519Abstract: Disclosed is a functionalizing method for the end functionalisation of trans-1,4 stereo-regular polydiene chains obtained by the coordination catalytic polymerisation of at least one conjugated diene monomer. It also relates to a polydiene having a trans-1,4 chain formation rate of at least 85%, preferably at least 90%, and an end functionalisation rate higher than 70%, preferably higher than 80%, and more preferably higher than 90%.Type: GrantFiled: July 11, 2018Date of Patent: April 25, 2023Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'ARTOIS, UNIVERSITÉ DE LILLE, ECOLE CENTRALE DE LILLE, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE LILLEInventors: Marc Visseaux, Philippe Zinck, Sébastien Georges, Yohan Champouret
-
Patent number: 11584943Abstract: The invention relates to a process for the recovery of CO2 by biological reduction comprising a step of bringing a liquid phase containing the bacterium Stenotrophomonas maltophilia into contact with a CO2-containing gas phase under conditions allowing the production of formate and/or methane from said CO2. The process according to the invention can be implemented in particular in a closed reactor or a semi-closed reactor or a continuous reactor, electrochemically assisted or not.Type: GrantFiled: June 4, 2019Date of Patent: February 21, 2023Assignees: UNIVERSITÉ DE MONTPELLIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIERInventors: Laurence Soussan, Azariel Ruiz-Valencia, Djahida Benmeziane, José Sanchez-Marcano, Marie-Pierre Belleville, Delphine Paolucci-Jeanjean
-
Patent number: 11541023Abstract: The invention relates to compounds exhibiting kallikrein inhibitory activity, and to compositions comprising at least one of these compounds for use in the treatment of diseases or disorders in which kallikrein activity is dysregulated, particularly neurodegenerative and inflammatory diseases.Type: GrantFiled: February 13, 2019Date of Patent: January 3, 2023Assignees: SARBONNE UNIVERSITE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE, ASSISTANCE PUBLIQUE—HÔPITAUX DE PARIS, INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE, UNIVERSITÉ DE MONTPELLIER, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIERInventors: Chahrazade El Amri, Feryel Soualmia, Nicolas Masurier, Sabrina Aït Amiri, Brahim Nait Oumesmar, Cyrille Deboux
-
Publication number: 20220356390Abstract: The invention relates to a dynamic method for determining the formation of a Winsor III microemulsion system, the method comprising the steps of: providing a mixture of an aqueous medium and a hydrocarbon medium in a chamber; continuously altering the concentration of at least one component in the mixture, while the ratio of the aqueous medium to the hydrocarbon medium remains constant and while stirring the mixture; and continuously measuring at least one physicochemical property of the mixture. The invention further relates to a device for determining the formation of a Winsor III microemulsion system.Type: ApplicationFiled: September 9, 2019Publication date: November 10, 2022Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE LILLE, UNIVERSITE DE LILLE, TotalEnergies OneTechInventors: Guillaume Lemahieu, Jesus Fermin Ontiveros, Jean-Marie Aubry, Valérie Molinier
-
Publication number: 20220289634Abstract: A filter including a porous support defining one or more channels therethrough, and a porous ceramic membrane layer on a surface of the porous support defining at least one of the one or more channels. The ceramic membrane layer includes an inorganic ceramic composition having the formula SiMpxpCyNzOmHn, where each Mp present is independently selected from a p-block element or a d-block element; p is an integer from 1 to 5; for each Mp present, xp is independently from about 0 to about 60; y is from about 0 to about 60; z is from about 0 to about 60; m is from about 0 to about 40; and n is zero or nonzero. At least one of y and z is nonzero when p is zero, and p is nonzero when y and z are both zero.Type: ApplicationFiled: May 26, 2022Publication date: September 15, 2022Applicants: Saudi Arabian Oil Company, Ecole Nationale Supérieure de Chimie de MontpelliInventors: Subhi Mohammed Hassan Al-Jeshi, Aziz Cherifi, David Cornu, Sophie Cerneaux
-
Patent number: 11439724Abstract: The invention relates to a device for adsorbing odours comprising an absorbent layer and an adsorbent layer, said adsorbent layer being provided with a material permeable to volatile organic compounds (VOCs) and an adsorbent particulate filler comprising at least one spice. Such a device is particularly useful for adsorbing and masking body odours.Type: GrantFiled: June 23, 2020Date of Patent: September 13, 2022Assignees: Institute Curie, Ecole Superieure De Physique Et De Chimie Industrielle (ESPCI), Ecole Nationale Superieure De Chimie De Paris (ENSCP), Centre National De La Recherche Scientifique, Cemag CareInventors: Aurélie Thuleau, Isabelle Fromantin, Vincent Semetey, José Dugay, Jean-François Le Meur
-
Patent number: 11388808Abstract: The present invention relates to a plasma reactor and more specifically to an plasma microreactor comprising a support, made at least partially of a dielectric material, the support comprising a gas inlet, a liquid inlet, at least a fluid outlet, a liquid microchannel in the support, a gas channel, at least a ground electrode, at least a high voltage electrode, separated from the gas channel by the dielectric material of the support, wherein said ground electrode and said high voltage electrode are arranged on opposite sides of the gas channel so as to be able to create an electric field inside the gas channel, wherein the liquid microchannel and the gas channel are contiguous and at least an opening is arranged between the liquid microchannel and the gas channel so as to form a fluid channel and to cause the liquid flow contact the gas flow and wherein the liquid flow is retained within the liquid microchannel by capillarity action.Type: GrantFiled: February 28, 2019Date of Patent: July 12, 2022Assignees: Paris Sciences et Lettres, Centre National de la Recherche Scientifique (CNRS), Sorbonne Universite, Ecole Nationale Supérieure de Chimie de ParisInventors: Julien Wengler, Stéphanie Ognier, Safwan Al Ayoubi, Michael Tatoulian
-
Publication number: 20220133392Abstract: The present invention relates to a microfluidic chip for attracting and destroying a specific biological element, said chip comprising: a reservoir (1) consisting of a matrix comprising a chemoattractant compound capable of attracting the biological element at least one network of microchannels (2) arranged between the reservoir (1) and the external environment (3) of the chip and allowing the chemoattractant compound to pass to said environment and the biological element present in said environment to pass to the reservoir (1) at least one electrode (4) arranged between the reservoir (1) and the network of microchannels (2) or at the same location as the network of microchannels (2), said electrode (4) being capable of generating an electric field so as to destroy the biological element during its passage to the reservoir (1).Type: ApplicationFiled: March 12, 2020Publication date: May 5, 2022Applicants: UNIVERSITE DE MONTPELLIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIERInventors: Benoît CHARLOT, Jean-Marie RAMIREZ, Sébastien MEANCE, Xavier GARRIC, Coline PINESE, Isabelle GUIRAUD
-
Patent number: 11299506Abstract: Chemical compounds are provided belonging to the group of nucleotide analogues. More specifically, acylnucleoside phosphonate compounds are disclosed and also their method of preparation and their use as medicaments, in particular for the prevention and/or the treatment of diseases caused by infection by an organism that is auxotrophic for purines, such as Plasmodium falciparum. Also disclosed are pharmaceutical compositions containing such compounds.Type: GrantFiled: March 21, 2018Date of Patent: April 12, 2022Assignees: UNIVERSITE DE MONTPELLIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIERInventors: Suzanne Peyrottes, Christian Perigaud, Sharon Wein-Grataud