Abstract: A peristaltic pump is presented comprising a housing and a rotor assembly supported by the housing. An occlusion bed is slideably mounted in the housing. A door is pivotable about a shaft, which is supported by the housing. A pinion gear is coupled to the shaft and engages a rack on the occlusion bed. Rotation of the shaft causes the occlusion bed to slide toward or away from the rotor assembly. An open portion of a tube retaining system is associated with the housing and a clamping portion of the tube retaining system is associated with the door. The open portion and the clamping portion of the tube retaining system are configured to secure flexible tubing therebetween when the door is in a closed position.