Abstract: Imidazoquinolines and imidazonaphthyridines with a substituent containing a functional group, e.g., an amide, sulfonamide, urea, or heterocyclyl group, at the 6, 7, 8, or 9-position, pharmaceutical compositions containing the compounds, intermediates, methods of making and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
Type:
Application
Filed:
February 10, 2006
Publication date:
April 16, 2009
Applicant:
Coley Pharmaceutial Group, Inc.
Inventors:
Michael J. Rice, Chad A. Haraldson, John F. Gerster, Joshua R. Wurst, Philip D. Heppner, Bryon A. Merrill, Tushar A. Kshirsagar