Abstract: Methods, systems, and computer readable media for predicting a spectrum, e.g., a UV-Vis spectrum, of a target molecule are disclosed. According to one aspect, a descriptor, such as a SMILES sequence or extended connectivity fingerprint, of the target molecule can be provided or generated and analyzed via a trained machine learning model, such as a trained long-short term memory (LSTM) model, to predict the spectrum of the target molecule. As determined via a variety of statistical measures, the methods, systems and computer readable media can predict the complete UV spectrum of a target molecule with high accuracy over the entire spectrum.

Abstract: Methods of treating or preventing diseases caused by viral infections via the administration of pyronaridine, quinacrine, and/or tilorone are described. The viral infections can be caused by viruses such as Marburg virus (MARV), Chikungunya virus (CHIKV), norovirus, Middle East Respiratory Syndrome coronavirus (MERS-CoV), and Nipah virus.

Abstract: Methods of treating or preventing diseases caused by viral infections via the administration of pyronaridine, quinacrine, and/or tilorone are described. The viral infections can be caused by viruses such as Marburg virus (MARV), Chikungunya virus (CHIKV), norovirus, Middle East Respiratory Syndrome coronavirus (MERS-CoV), and Nipah virus.

Abstract: Methods of modulating the interaction between ?-amyloid and ?7-nAChR are provided. Aspects of the methods include administering to the subject an effective amount of a naphthalene derivative active agent. Compositions and kits for practicing the subject methods are also provided. The methods, compositions and kits find use in treating a variety of applications, such as treating a subject for a neurodegenerative disease, e.g., Alzheimer's disease.