Patents Assigned to Collaborative Group, Ltd.
  • Beta (1-3) -glucan diagnostic assays
    Publication number: 20010051717
    Abstract: Methods of isolating &bgr;(1-3)-glucan or &bgr;(1-3)-glucan-containing organisms in a sample, or of detecting the presence of &bgr;(1-3)-glucan or &bgr;(1-3)-glucan-containing organisms in a sample, utilizing binding agents for &bgr;(1-3)-glucan, such as LacCer, GalCer, globotriaosylceramide and asialoganglioside-GM1, are described. Methods of diagnosing fungal infection, by detecting &bgr;(1-3)-glucan or &bgr;(1-3)-glucan-containing organisms, are also described. Antibodies and kits useful in the methods are also disclosed.
    Type: Application
    Filed: June 19, 2001
    Publication date: December 13, 2001
    Applicant: Collaborative Group, Ltd.
    Inventors: Eric M. Wakshull, William M. Mackin, Janet W. Zimmerman, Leslie W. Fisette
  • Activation of signal transduction by underivatized, aqueous soluble . .beta(1-3)-Glucan
    Patent number: 6090938
    Abstract: A preparation containing a receptor for underivatized, aqueous soluble .beta.(1-3)-glucan is disclosed, along with characterization of the receptor for underivatized, aqueous soluble .beta.(1-3)-glucan. Also described are assays for identifying agents which alter the effect of underivatized, aqueous soluble .beta.(1-3)-glucan on activation of signal transduction pathways and agents identified thereby.
    Type: Grant
    Filed: June 14, 1996
    Date of Patent: July 18, 2000
    Assignee: Collaborative Group, Ltd.
    Inventors: Eric Wakshull, William M. Mackin, Janet Zimmerman