Patents Assigned to COLLEGE DE FRANCE
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Patent number: 11962037Abstract: The present application relates to a proton exchange membrane for fuel cell, said membrane having self-regenerating properties, to cells comprising said membranes, and to the manufacturing method thereof via electrospinning.Type: GrantFiled: January 21, 2021Date of Patent: April 16, 2024Assignees: SYMBIO, COLLEGE DE FRANCE, SORBONNE UNIVERSITÉ, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Christophe Vacquier, Nathalia Rovira, Christophe Baverel, Christel Laberty-Robert, Laura Coustan, Clément Sanchez
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Publication number: 20240053345Abstract: The present invention relates to a polypeptide X1X2-RK-X3X4-KK-X5X6X7X8X9X10-KR-X11X12 SEQ ID NO: 1 able to bind selectively to cells expressing proteoglycans comprising glycosaminoglycans as heparin or heparan sulfate. The linkage of said polypeptide to an internalization peptide enables the polypeptide to be internalized. The present invention further relates to a conjugated polypeptide comprising said polypeptide and a biomarker, to a cell penetrating polypeptide comprising said polypeptide, optionally a linker and a cell internalization peptide and a chimeric polypeptide comprising said cell penetrating polypeptide and one or more biological cargos.Type: ApplicationFiled: December 17, 2020Publication date: February 15, 2024Applicants: SORBONNE UNIVERSITE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE NORMALE SUPERIEURE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), COLLEGE DE FRANCEInventors: Sandrine Sagan, Alain Joliot, Astrid Walrant, Ludovic Carlier, Sébastien Cardon
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Patent number: 11559781Abstract: A manufacturing process that includes spray-drying a liquid composition based on liquid residues derived from a chemical extraction of clinker to form a material with a high specific surface area. Also, a material based on clinker residues having a high specific surface area ranging from 200 m2.g?1 to 900 m2.g?1 and a mesopore size ranging from 2 nm to 50 nm. Further, the use of a material having a high specific surface area for the absorption of pollutants species.Type: GrantFiled: March 9, 2018Date of Patent: January 24, 2023Assignees: SARP INDUSTRIES, COLLEGE DE FRANCEInventors: Clément Sanchez, Cédric Boissiere, Lionel Nicole, Hiva Baradari, Xavier Chaucherie, Bruno Gilardin
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Patent number: 11519072Abstract: A sol-gel method for producing an anti-corrosion coating consisting of at least one layer of an oxide on a metal substrate. A non-aqueous solution of a precursor of the oxide is prepared and deposited on one surface at least of the metal substrate in order to cover said surface at least partially with a film comprising the precursor of the oxide. Hydrolysis-condensation of the precursor of the oxide is carried out by exposing the film to a humid atmosphere in order to form an oxide network in the film. Then, a treatment for stabilizing the film on the surface of the substrate is carried out, followed by a heat treatment of the surface of the metal substrate in order to crystallize the network of oxide and form the anti-corrosion coating.Type: GrantFiled: December 20, 2017Date of Patent: December 6, 2022Assignees: ELECTRICITE DE FRANCE, SORBONNE UNIVERSITE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS—, COLLEGE DE FRANCEInventors: Adele Astorg, Xavier Crozes, Lionel Nicole, Clement Sanchez
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Patent number: 11482729Abstract: Some embodiments include an electrolyte composition for a battery using sodium ions as electrochemical vector, to the use of such an electrolyte composition as non-aqueous liquid electrolyte in a sodium-ion battery and to a sodium-ion battery comprising such a non-aqueous liquid electrolyte. In some embodiments, the amount of (oxalato)borate ranges from 0.05 to 10 wt. %, relative to the total weight of the electrolyte composition.Type: GrantFiled: October 11, 2018Date of Patent: October 25, 2022Assignees: Centre national de la recherche scientifique, College de france, Sorbonne UniversiteInventors: Guochun Yan, Jean-Marie Tarascon
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Patent number: 11357816Abstract: The invention relates to new compounds that mimic Glycosaminoglycans and are able to control interaction between Glycosaminoglycans with their effector molecules. The compounds of the invention are peptides and are able to prevent or reduce the binding of at least one effector molecule with at least one glycosaminoglycan. The compounds according to the invention can be used as drug, in particular for the stimulation of the neurogenesis and more generally to treat nervous system related pathologies.Type: GrantFiled: June 17, 2019Date of Patent: June 14, 2022Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), SORBONNE UNIVERSITE, ECOLE NORMALE SUPERIEURE, COLLEGE DE FRANCEInventors: Jean-Maurice Mallet, Solange Lavielle, Rodrigue Marquant, Alain Prochiantz, Ariel Di Nardo, Damien Testa
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Patent number: 11345658Abstract: The present invention relates to compounds, to compositions comprising the same, to methods for preparing the compounds, and the use of these compounds in therapy. In particular, the present invention relates to a compound that is useful in the treatment and prevention of primary and secondary arterial hypertension, ictus, myocardial ischaemia, cardiac and renal insufficiency, myocardial infarction, peripheral vascular disease, diabetic proteinuria, Syndrome X and glaucoma.Type: GrantFiled: March 11, 2020Date of Patent: May 31, 2022Assignees: QUANTUM GENOMICS, INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, COLLEGE DE FRANCEInventors: Fabrice Balavoine, Delphine Compere, Mathilde Keck, Yannick Marc, Catherine Llorens-Cortes, Solène E. Boitard
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Publication number: 20220127736Abstract: The present invention relates to an electrolysis device comprising an anode and a cathode, wherein the anode and the cathode each are an electrode comprising an electrically conductive support of which at least a part of the surface is covered by a metal deposit of copper, wherein the surface of the metal deposit is in an oxidized, sulfurated, selenated and/or tellurized form and the metal deposit has a specific surface area greater than or equal to 1 m2/g. The present invention relates also to a method for reducing CO2 into hydrocarbons using an electrolysis device according to the invention. The method according to the invention comprises: a) providing an electrolysis device according to the invention; b) exposing the cathode of said electrolysis device to a CO2-containing aqueous catholyte solution; c) exposing the anode of said electrolysis device to an aqueous anolyte solution; and d) applying an electrical current between the anode and the cathode in order to reduce the carbon dioxide into hydrocarbons.Type: ApplicationFiled: November 21, 2019Publication date: April 28, 2022Applicants: Paris Sciences et Lettres - Quartier Latin, College de France, Centre National de la Recherche Scientifique (CNRS), Sorbonne Universite, College de FranceInventors: Marc Fontecave, Victor Mougel, Huan Tran Ngoc, Daniel Alves Dalla Corte, Sarah Lamaison, Lukas Lutz
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Publication number: 20220013772Abstract: A positive electrode active material for a sodium-ion battery has the following formula: NaxNi0.5-yCuyMn0.5-zTizO2, in which: -x varies from 0.9 to 1; -y varies from 0.05 to 0.1; -z varies from 0.1 to 0.3. When z is equal to 0.1 and x is equal to 1, then y is not equal to 0.05.Type: ApplicationFiled: October 10, 2019Publication date: January 13, 2022Applicants: RENAULT s.a.s., CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), COLLEGE DE FRANCE, SORBONNE UNIVERSITEInventors: Mohamed CHAKIR, Sathiya MARIYAPPAN, Jean-Marie TARASCON, Qing WANG
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Publication number: 20210379144Abstract: The present disclosure relates to the use of a homeoprotein or a recombinant vector encoding said protein for treating or preventing DNA damage and/or cellular aging. In particular, the invention concerns the use of Engrailed for the treatment of Parkinson disease.Type: ApplicationFiled: June 16, 2021Publication date: December 9, 2021Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), COLLEGE DE FRANCE, SORBONNE UNIVERSITEInventor: Alain Prochiantz
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Patent number: 11192907Abstract: The present invention relates to a novel compound, to a composition comprising the same, to methods for preparing the compound, and the use of this compound in therapy. In particular, the present invention relates to a compound that is useful in the treatment and prevention of primary and secondary arterial hypertension, ictus, myocardial ischaemia, cardiac and renal insufficiency, myocardial infarction, peripheral vascular disease, diabetic proteinuria, Syndrome X and glaucoma.Type: GrantFiled: October 25, 2019Date of Patent: December 7, 2021Assignees: QUANTUM GENOMICS, INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, COLLEGE DE FRANCEInventors: Fabrice Balavoine, Delphine Compere, Catherine Llorens-Cortes, Yannick Marc
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Patent number: 10998549Abstract: The invention relates to a process for the preparation of sodium-based solid compounds, such as sodium-based solid alloys and sodium-based crystalline phases by ball-milling using metallic sodium as starting material. The invention also relates to some sodium-based crystalline P?2-phases and to Na-based vanadium phosphates phases (Na(3+y)V2(PO4)3) with 0<y?3 and Na-based vanadium fluorophosphates phases (Na(3+z)V2(PO4)2F3) with 0<z?3, in particular Na4V2(PO4)2F3, obtained by such a process and to their use, as active material for positive electrode, in a Na-ion battery.Type: GrantFiled: June 15, 2016Date of Patent: May 4, 2021Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE TOULOUSE III—PAUL SABATIER, SORBONNE UNIVERSITE, COLLEGE DE FRANCEInventors: Jean-Marie Tarascon, Patrick Rozier, Biao Zhang, Romain Dugas
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Patent number: 10730035Abstract: A nanostructured material consisting essentially of boron. The material is in amorphous form and comprising aggregates of boron nanoparticles. A method of preparation thereof and the uses thereof.Type: GrantFiled: June 23, 2016Date of Patent: August 4, 2020Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, COLLEGE DE FRANCEInventors: Clément Sanchez, Christel Gervais Stary, David Portehault, Guillaume Gouget
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Patent number: 10637059Abstract: The present invention relates to a method for producing a positive electrode composite material comprising at least one Na-based positive electrode active material and Na3P for a battery using sodium ions as electrochemical vector, to a positive electrode comprising such a positive electrode composite material, and to the Na-ion battery comprising such a positive electrode.Type: GrantFiled: June 15, 2016Date of Patent: April 28, 2020Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, COLLEGE DE FRANCE, SORBONNE UNIVERSITE, UNIVERSITE TOULOUSE III—PAUL SABATIERInventors: Jean-Marie Tarascon, Patrick Rozier, Biao Zhang
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Publication number: 20200070122Abstract: A process for manufacturing a material with a high specific surface area, including a step of spraying a liquid composition based on liquid residues derived from a chemical extraction of clinker, to a material based on clinker residues having a high specific surface area ranging from 200 m2·g?1 to 900 m2·g?1 and also by a mesopore size ranging from 2 nm to 50 nm, and to the use of materials for the absorption of pollutants species.Type: ApplicationFiled: March 9, 2018Publication date: March 5, 2020Applicants: SARP INDUSTRIES, COLLEGE DE FRANCEInventors: Clément SANCHEZ, Cédric BOISSIERE, Lionel NICOLE, Hiva BARADARI, Xavier CHAUCHERIE, Bruno GILARDIN
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Publication number: 20190338423Abstract: A sol-gel method for producing an anti-corrosion coating consisting of at least one layer of an oxide on a metal substrate. A non-aqueous solution of a precursor of the oxide is prepared and deposited on one surface at least of the metal substrate in order to cover said surface at least partially with a film comprising the precursor of the oxide. Hydrolysis-condensation of the precursor of the oxide is carried out by exposing the film to a humid atmosphere in order to form an oxide network in the film. Then, a treatment for stabilizing the film on the surface of the substrate is carried out, followed by a heat treatment of the surface of the metal substrate in order to crystallize the network of oxide and form the anti-corrosion coating.Type: ApplicationFiled: December 20, 2017Publication date: November 7, 2019Applicants: ELECTRICITE DE FRANCE, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE- CNRS-, COLLEGE DE FRANCEInventors: Adele Astorg, Xavier Crozes, Lionel Nicole, Clement Sanchez
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Patent number: 10437561Abstract: The invention relates to a stochastic-type microprocessor. In some embodiments, the microprocessor comprises an elementary stochastic computation module able to receive, as input, two random and independent binary input signals each representing a binary coding of two respective given input probability values, and able to generate, as output, a random binary output signal. The elementary module comprises: a programmable logic unit, able to combine two input signals to generate an output signal; an addressable memory, able to store an output probability value coded by an output signal generated by the logic unit; a first stochastic clock, able to produce a first clock signal; a second stochastic clock, able to produce a second clock signal.Type: GrantFiled: June 17, 2016Date of Patent: October 8, 2019Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, COLLEGE DE FRANCEInventors: Jacques Droulez, Pierre Bessiere
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Publication number: 20190247461Abstract: The present invention relates to the use of a homeoprotein or a recombinant vector encoding said protein for treating or preventing DNA damage and/or cellular aging. In particular, the invention concerns the use of Engrailed for the treatment of Parkinson disease.Type: ApplicationFiled: September 23, 2016Publication date: August 15, 2019Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), COLLEGE DE FRANCE, SORBONNE UNIVERSITEInventor: Alain Prochiantz
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Patent number: 10342851Abstract: The invention relates to the use of an Engrailed protein as a medicament for increasing dopamine synthesis by dopaminergic neurons, in particular in the management of conditions associated with a decrease of dopamine levels without loss of dopaminergic neurons.Type: GrantFiled: March 16, 2018Date of Patent: July 9, 2019Assignees: Centre National de la Recherche Scientifique, College de FranceInventors: Alain Prochiantz, Kenneth Moya, Rajiv Joshi
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Patent number: 10322162Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of ischemic conditions. In particular, the present invention relates to a method of treating an ischemic condition in a subject in need thereof comprising administering the subject with a polypeptide comprising an amino acid sequence having at least 70% of identity with the amino acid sequence ranging from the amino acid residue at position 186 to the amino acid residue at position 406 in SEQ ID NO: 1.Type: GrantFiled: January 6, 2016Date of Patent: June 18, 2019Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), COLLEGE DE FRANCE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE PARIS-EST CRETEIL VAL DE MARNE, ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS (APHP), ECOLE NATIONALE VETERINAIRE D'ALFORT (ENVA)Inventors: Stéphane Germain, Alain Berdeaux, Renaud Tissier, Bijan Ghaleh-Marzban, Catherine Monnot, Ariane Galaup