Abstract: The present invention relates to compositions containing quinazolinones. More particularly, the present invention relates to a composition for the treatment of renal fibrosis. This composition includes, as an active ingredient, a quinazolinone derivative such as halofurginone, which is shown herein to slow or prevent progression of renal fibrosis in vivo thereby mitigating or preventing end-stage renal failure.
Type:
Application
Filed:
November 24, 2003
Publication date:
September 2, 2004
Applicants:
Hadasit, State Of Israel, Collgard
Inventors:
Arnon Nagler, Israel Vlodavsky, Mark Pines, Shai Yarkoni