Patents Assigned to Colorado School of Mines
  • Patent number: 8154727
    Abstract: Laser light is confined in a hollow waveguide between two highly reflective mirrors. This waveguide cavity is used to conduct Cavity Ringdown Absorption Spectroscopy of loss mechanisms in the cavity including absorption or scattering by gases, liquid, solids, and/or optical elements.
    Type: Grant
    Filed: March 3, 2008
    Date of Patent: April 10, 2012
    Assignee: Colorado School of Mines
    Inventors: Chris Dreyer, Greg S. Mungas
  • Publication number: 20120052006
    Abstract: The present disclosure is directed generally to gold/lanthanide nanoparticle conjugates, such as gold/gadolinium nanoparticle conjugates, nanoparticle conjugates including polymers, nanoparticle conjugates conjugated to targeting agents and therapeutic agents, and their use in targeting, treating, and/or imaging disease states in a patient.
    Type: Application
    Filed: February 17, 2010
    Publication date: March 1, 2012
    Applicant: COLORADO SCHOOL OF MINES
    Inventors: Stephen G. Boyes, Misty D. Rowe
  • Patent number: 8119205
    Abstract: The invention is directed to a method for producing Palladium alloy composite membranes that are useful in applications that involve the need to separate hydrogen from a gas mixture. The method includes providing a substrate for supporting a palladium alloy film, seeding the support surface with palladium crystallites to produce an activated surface, first plating, over the activated surface, a palladium film, second plating, over the palladium film, an alloying material other than silver, and annealing the porous substrate, palladium film, and alloying material so that there is intermetallic diffusion of the alloying material into the palladium film to produce a palladium alloy film over the porous substrate.
    Type: Grant
    Filed: May 3, 2006
    Date of Patent: February 21, 2012
    Assignee: Colorado School of Mines
    Inventors: Fernando Roa, J. Douglas Way, Stephen N. Paglieri
  • Patent number: 8119976
    Abstract: A system, method, and device for re-orienting and/or deforming cells and other objects is provided. The system, method, and device may include a high-throughput setup that facilitates the ability to orient, deform, analyze, measure, and/or tag objects at a substantially higher rate than was previously possible. A relatively large number of cells and other objects can be deformed, by optical forces for example, as the cells and other objects a flowed through the system.
    Type: Grant
    Filed: July 2, 2008
    Date of Patent: February 21, 2012
    Assignee: Colorado School of Mines
    Inventors: Jeff Squier, David W. M. Marr, Robert Applegate, Tor Vestad, Justin Chichester
  • Publication number: 20120034700
    Abstract: Methods to radiolabel natural organic matter by reduction with a hydrogen labeled reducing agent, and compositions, are provided.
    Type: Application
    Filed: October 18, 2011
    Publication date: February 9, 2012
    Applicant: COLORADO SCHOOL OF MINES
    Inventors: Ruth M. Tinnacher, Bruce D. Honeyman
  • Patent number: 8101243
    Abstract: The invention provides thin, hydrogen-permeable, sulfur-resistant membranes formed from palladium or palladium-alloy coatings on porous, ceramic or metal supports. Also disclosed are methods of making these membranes via sequential electroless plating techniques, wherein the method of making the membrane includes decomposing any organic ligands present on the substrate, reducing the palladium crystallites on the substrate to reduced palladium crystallites, depositing a film of palladium metal on the substrate and then depositing a second, gold film on the palladium film. These two metal films are then annealed at a temperature between about 200° C. and about 1200° C. to form a sulfur-resistant, composite PdAu alloy membrane.
    Type: Grant
    Filed: June 25, 2007
    Date of Patent: January 24, 2012
    Assignee: Colorado School of Mines
    Inventors: J. Douglas Way, Mark Lusk, Paul Thoen
  • Patent number: 8092990
    Abstract: Methods and apparatus are provided for detection of microorganisms in a sample. Methods and apparatus of the invention are based on the specificity that phage, for example bacteriophage, have for target microorganisms, for example bacterium. Typically, phage adsorption to target microorganisms act as signal, or a signal target, for the presence of the target microorganism. Typically, the phage are labeled with a detectable signal. Apparatus of the invention are directed toward concentrating the phage adsorbed microorganisms at a predetermined site for flag dependent observation.
    Type: Grant
    Filed: March 31, 2006
    Date of Patent: January 10, 2012
    Assignee: Colorado School of Mines
    Inventor: Kent J. Voorhees
  • Patent number: 8039266
    Abstract: Methods to radiolabel natural organic matter by reduction with a hydrogen labeled reducing agent, and compositions, are provided.
    Type: Grant
    Filed: September 17, 2007
    Date of Patent: October 18, 2011
    Assignee: Colorado School of Mines
    Inventors: Ruth M. Tinnacher, Bruce D. Honeyman
  • Patent number: 8025932
    Abstract: Ta2O5 and Al2O3 thin films were fabricated by pulsed plasma-enhanced chemical vapor deposition (PECVD) with simultaneous delivery of O2 and the metal precursor. By appropriately controlling the gas-phase environment self-limiting deposition at controllable rates (˜1 ?/pulse) was obtained. The process was insensitive to substrate temperature, with a constant deposition rate observed from 90-350° C. As-deposited Ta2O5 films under these conditions displayed good dielectric properties. Performance improvements correlate strongly with film density and composition as measured by spectroscopic ellipsometry and Fourier transform infrared spectroscopy. Pulsed PECVD eliminates the need for gas actuation and inert purge steps required by atomic layer deposition.
    Type: Grant
    Filed: February 5, 2008
    Date of Patent: September 27, 2011
    Assignee: Colorado School of Mines
    Inventors: Colin Wolden, Michael T. Seman
  • Publication number: 20110227006
    Abstract: The invention relates generally to a polymeric composition and a method for making and using the polymeric composition, more specifically to a polymeric composition and a method for making and using the polymeric composition in the form of a membrane.
    Type: Application
    Filed: March 21, 2011
    Publication date: September 22, 2011
    Applicant: COLORADO SCHOOL OF MINES
    Inventors: Gregory J. Schlichting, Andrew M. Herring
  • Patent number: 8020428
    Abstract: A system and method for determining a fluid property for a fluid flowing in a pipe may include sensing baseline vibrations when test fluids with known values for a fluid property (e.g., fluid density or fluid viscosity) flow through the pipe, or computer modeling the baseline vibrations. The baseline vibrations are analyzed via cross-correlation and/or deconvolution to separate the fluid filled pipe's baseline combined structural response from excitation and base coupling effects. During field or other operations, sensors may take vibrational readings along the pipe when an operational fluid (e.g., drilling fluid) flows through the pipe. The operational vibrations may be analyzed via cross-correlation and/or deconvolution to separate the operational combined structural response of the fluid filled pipe from excitation and base coupling effects. The baseline and operational structural responses may compared.
    Type: Grant
    Filed: April 4, 2008
    Date of Patent: September 20, 2011
    Assignee: Colorado School of Mines
    Inventor: Roelof K. Snieder
  • Publication number: 20110201076
    Abstract: A reusable composite paramagnetic particle may comprise a paramagnetic core encased by a protective material to which is grafted a tendril layer comprising a plurality of polymeric chains. The polymeric chains may be designed to interact with a microorganism. The interaction between the microorganism and the polymeric chain may be electrostatic. The nanoparticle may be used in a method to isolate or recover microorganisms from solutions using an externally applied magnetic field.
    Type: Application
    Filed: January 21, 2011
    Publication date: August 18, 2011
    Applicant: COLORADO SCHOOL OF MINES
    Inventor: Hongjun Liang
  • Patent number: 7972773
    Abstract: The invention is directed to a method for detecting low concentrations of bacteria in liquid solution that may or may not be complex liquid solutions. In one embodiment, immunomagnetic separation (IMS) is used to separate target bacterium that may be in a liquid mixture from other constituents in the mixture. A low concentration of a bacteriophage for the target bacteria is subsequently used to infect target bacterial cells that have been captured using the IMS technique. If at least a certain concentration of target bacterium are present, the bacteriophage will multiply to a point that is detectable. Matrix assisted laser desorption ionization/time-of-flight-mass spectrometry (MALDI/TOF-MS) is then used to produce a mass spectrum that is analyzed to determine if one or more proteins associated with the bacteriophage are present, thereby indirectly indicating that target bacterium were present in the liquid mixture.
    Type: Grant
    Filed: January 23, 2007
    Date of Patent: July 5, 2011
    Assignee: Colorado School of Mines
    Inventors: Angelo J. Madonna, Kent J. Voorhees, Jon C. Rees
  • Patent number: 7949210
    Abstract: This invention provides fundamental science and novel device architectures for surface plasmon (SP)-based, complementary metal oxide semiconductor (CMOS)-compatible, optical elements such as modulators, couplers, and switches. The primary focus of the work is on waveguides based on an ultra-long-range surface plasmon (ULRSP) waveguide mode recently discovered by our team. This mode exists at the metal-dielectric interfaces in a silicon-oxide-metal-silicon layer structure. While initial work focuses on noble metals to support the ULRSP, our analysis shows Si processing-compatible metals such as Cu and Al can also be used. Our modeling has also shown that variation in the thickness of the oxide layer can be used to give unprecedented propagation lengths in such structures. Electrically-induced free carrier modulation of the dielectric constant in the Si adjacent to the oxide can modulate the waveguide properties allowing novel Si-compatible electro-optic devices to be created.
    Type: Grant
    Filed: October 9, 2007
    Date of Patent: May 24, 2011
    Assignee: Colorado School of Mines
    Inventors: Charles G. Durfee, Reuben T. Collins, Thomas E. Furtak
  • Patent number: 7930152
    Abstract: A method for simulating a partial differential equation to perform image and signal processing. The method utilizes quantum and classical lattice gas processes to simulate the partial differential equation. The lattice gas processes may be run on a type I quantum computer, type II quantum computer or a classical computer. A system for simulating and solving a partial differential equation comprising a quantum computer and a classical processor.
    Type: Grant
    Filed: July 12, 2007
    Date of Patent: April 19, 2011
    Assignee: Colorado School of Mines
    Inventors: Mark W. Coffey, Gabriel G. Colburn
  • Patent number: 7867633
    Abstract: The invention provides coatings to achieve the best accommodation of chemical, physical, and mechanical properties desired in high performance and reliable glass molding and forming tools. The substrate material can be any ordinary die or tool material such as cast iron, stainless steel, platinum, tungsten carbide and silicon. A simple coating architecture consisting of a titanium adhesion layer and a Ni—Al—N or Ti—B—C—N working layer is provided. A NiAl working layer can meet the requirements of wear resistance in which abrasive and/or erosive wear is relatively low, while a Ti—B—C—N working layer is sufficient for processes operating at relatively low temperature or in vacuum or a protective environment. The coating architectures, from the coating/substrate interface to the outer most surface of the coating include an inner adhesion layer, an outer working layer and, optionally, one or more functionally graded material layers. The invention also provides methods of making these coatings.
    Type: Grant
    Filed: June 6, 2005
    Date of Patent: January 11, 2011
    Assignee: Colorado School of Mines
    Inventors: John Moore, Dalong Zhong, Jianliang Lin
  • Publication number: 20100294670
    Abstract: The invention relates generally to elemental boron, particularly to elemental boron having a high purity level and to a method of recovering elemental boron by the electrolysis of a molten boron-containing electrolyte.
    Type: Application
    Filed: May 14, 2010
    Publication date: November 25, 2010
    Applicant: COLORADO SCHOOL OF MINES
    Inventors: Patrick R. Taylor, Judith C. Gomez
  • Publication number: 20100283496
    Abstract: A system and method for measuring recombination lifetime of a photoconductor or semiconductor material in real time and without physically contacting the material involving positioning the sample material between a transmitter and a receiver so that electromagnetic signals, preferably radio frequency signals, traveling from the transmitter to the receiver pass through the sample material. The electromagnetic signals are modulated as they pass through the sample material depending on the carrier density and conductivity of the sample material. The modulated electromagnetic signals received by the receiver are then analyzed to determine the carrier recombination lifetime of the sample material.
    Type: Application
    Filed: January 27, 2010
    Publication date: November 11, 2010
    Applicant: Colorado School of Mines
    Inventors: Richard Keith Ahrenkiel, Donald John Dunlavy
  • Patent number: 7736616
    Abstract: The invention provides CVD-based methods for growing single-walled or multi-walled carbon nanotubes. In the methods of the invention, the nanotube growth environment is separated from the carbon-containing gas feed environment using a membrane which is substantially impermeable to gas flow but permits diffusion of carbon through the membrane. A catalyst for carbon nanotube growth is located on the growth side of the membrane while a catalyst for decomposition of carbon-containing gas is located on the feed side of the membrane. A path for diffusion of carbon through the membrane is provided between the growth and decomposition catalysts. Control of the size and shape of the carbon nanotube growth catalyst enables control over the nanotube structure formed.
    Type: Grant
    Filed: July 14, 2006
    Date of Patent: June 15, 2010
    Assignee: Colorado School of Mines
    Inventors: Mark Thomas Lusk, G. Louis Hornyak, Michael Thomas Burke
  • Patent number: 7704320
    Abstract: The methods provided use external fields such as light and electricity as a means of directing the crystallization of concentrated colloidal systems. Not only can nucleation be directed, crystal melting can be carefully controlled and light-induced crystal diffraction used as a means of directing light propagation. A number of factors play a significant role on the crystallization rate and location, including the intensity of the light field, the magnitude of the electric field, the colloid concentration, the colloid size, and the colloid composition. In varying these parameters, kinetics in these processes are extremely fast when compared to traditional colloidal crystallization approaches.
    Type: Grant
    Filed: May 3, 2004
    Date of Patent: April 27, 2010
    Assignee: Colorado School of Mines
    Inventors: David W. M. Marr, Tieying Gong, David Wu