Patents Assigned to COLUMBIA LABORATORIES (BERMUDA) LIMITED
  • Progestin therapy for maintaining amenorrhea
    Publication number: 20010031747
    Abstract: The present invention teaches that daily, cyclical vaginal delivery of progestin may be used to provide regular, predictable withdrawal bleeding during hormone replacement therapy. The present invention also teaches that constant administration of progestin in a water-insoluble, water-swellable cross-linked polycarboxylic acid polymer may be used to maintain amenorrhea. Either regimen is accompanied by a significant decrease in adverse side effects.
    Type: Application
    Filed: April 3, 2001
    Publication date: October 18, 2001
    Applicant: COLUMBIA LABORATORIES (BERMUDA) LIMITED
    Inventors: Dominique deZiegler, William J. Bologna, Howard L. Levine