Abstract: The oxygen generation system includes a chemical oxygen generator that creates oxygen through an exothermic chemical reaction that creates sufficient heat to pose a serious risk to a user. The oxygen generation system therefore includes a containment layer to permit safer administration of oxygen from a chemical oxygen generator by shielding a user from and/or dissipating the heat generated by the chemical generator. The oxygen generation system may be handheld and portable for use in extreme, remote, and/or hostile conditions, locations, environments, and situations with a simple activation method easily operated under stress without any preparation or maintenance.