Patents Assigned to CombinatoRx, Inc.
  • Methods and reagents for the treatment of metabolic disorders
    Patent number: 7795310
    Abstract: The invention features compositions, methods, and kits for the treatment of metabolic disorders such as diabetes and obesity.
    Type: Grant
    Filed: June 30, 2005
    Date of Patent: September 14, 2010
    Assignee: CombinatoRx, Inc.
    Inventors: Margaret S. Lee, Grant R. Zimmermann, Alyce L. Finelli, Daniel Grau, Curtis Keith, M. James Nichols
  • Therapeutic regimens for the treatment of immunoinflammatory disorders
    Publication number: 20090075955
    Abstract: The invention features pharmaceutical compositions and dosing regimens for the treatment of immunoinflammatory disorders.
    Type: Application
    Filed: September 17, 2008
    Publication date: March 19, 2009
    Applicant: CombinatoRx, Inc.
    Inventor: Mahesh Padval
  • Methods and Reagents for the Treatment of Inflammatory Disorders
    Publication number: 20090075951
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering a tricyclic compound and, optionally, a corticosteroid or other compound to the patient. The invention also features a pharmaceutical composition containing a tricyclic compound and a corticosteroid or other compound for the treatment or prevention of an immunoinflammatory disorder.
    Type: Application
    Filed: November 20, 2008
    Publication date: March 19, 2009
    Applicant: CombinatoRx, Inc.
    Inventors: Benjamin A. Auspitz, Alexis Borisy, Jason Fong, Nicole Hurst, Edward Roydon Jost-Price, Curtis T. Keith, Palaniyandi Manivasakam, Robyn Sackeyfio, Michael S. Slavonic, Brendan Smith, Grant R. Zimmermann
  • Combinations for the treatment of immunoinflammatory disorders
    Patent number: 7253155
    Abstract: The invention features a method for treating a patient having an immunoinflammatory disorder, by administering to the patient (i) a tetra-substituted pyrimidopyrimidine, and (ii) a corticosteroid simultaneously or within 14 days of each other in amounts sufficient to reduce or inhibit immunoinflammation.
    Type: Grant
    Filed: October 4, 2002
    Date of Patent: August 7, 2007
    Assignee: CombinatoRx, Inc.
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmerman, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael A. Foley
  • Methods and reagents for the treatment of immunoinflammatory disorders
    Publication number: 20070010502
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents.
    Type: Application
    Filed: September 7, 2006
    Publication date: January 11, 2007
    Applicant: CombinatoRx Inc.
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmermann, Edward Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael Foley, Michael Slavonic, Brendan Smith, Benjamin Auspitz
  • Methods and reagents for the treatment of inflammatory disorders
    Publication number: 20060286177
    Abstract: The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering bufexamac and a corticosteroid or other compound to the patient. The invention also features a pharmaceutical composition containing bufexamac and a corticosteroid or other compound for the treatment or prevention of an immunoinflammatory disorder.
    Type: Application
    Filed: June 16, 2006
    Publication date: December 21, 2006
    Applicant: CombinatoRx, Inc.
    Inventors: Edward Jost-Price, Garry Nolan, Grant Zimmermann
  • Combinations of drugs for the treatment of neoplastic disorders
    Patent number: 7148216
    Abstract: The invention features a method for treating a patient having a cancer or other neoplasm by administering to the patient two compounds simultaneously or within 14 days of each other in amounts sufficient to treat the patient.
    Type: Grant
    Filed: December 28, 2004
    Date of Patent: December 12, 2006
    Assignee: CombinatoRx, Inc.
    Inventors: Alexis Borisy, Curtis Keith, Michael A. Foley, Brent R. Stockwell
  • Methods and reagents for the treatment of metabolic disorders
    Publication number: 20060069161
    Abstract: The invention features compositions, methods, and kits for the treatment of metabolic disorders such as diabetes and obesity.
    Type: Application
    Filed: June 30, 2005
    Publication date: March 30, 2006
    Applicant: CombinatoRx, Inc.
    Inventors: Margaret Lee, Grant Zimmermann, Alyce Finelli, Daniel Grau, Curtis Keith, M. Nichols
  • Combinations for the treatment of inflammatory disorders
    Patent number: 6897206
    Abstract: The invention features a method for treating a patient having an inflammatory disorder, by administering to the patient (i) a tricyclic antidepressant (e.g., amoxapine); and (ii) a corticosteroid (e.g., prednisolone) simultaneously or within 14 days of each other in amounts sufficient to reduce or inhibit inflammation.
    Type: Grant
    Filed: July 9, 2002
    Date of Patent: May 24, 2005
    Assignee: CombinatoRx, Inc.
    Inventors: Robyn Sackeyfio, Jason Fong, Nicole Hurst, Palaniyandi Manivasakam, Edward Roydon Jost-Price, Grant Zimmermann, Curtis Keith, Alexis Borisy
  • Combinations of drugs for the treatment of neoplastic disorders
    Patent number: 6846816
    Abstract: The invention features a method for treating a patient having a cancer or other neoplasm by administering to the patient two compounds simultaneously or within 14 days of each other in amounts sufficient to treat the patient.
    Type: Grant
    Filed: January 21, 2003
    Date of Patent: January 25, 2005
    Assignee: CombinatoRx, Inc.
    Inventors: Alexis Borisy, Curtis Keith, Michael A. Foley, Brent R. Stockwell