Abstract: A multiplexed capillary electrophoresis (CE) method using fluorescence detection for a plurality of samples is improved economically and in terms of instrument complexity by irradiating the plurality of samples with a single non-coherent light source as the excitation light source for all of the channels. The preferred light source is a light-emitting-diode (LED).
Abstract: A multiplexed, absorbance-based electrophoresis system for analyzing multiple samples simultaneously without use of a mask or slit comprising a light source, a planar array of capillary tubes and a detector positioned off-axis with the light source and positioned on-axis with and parallel to the planar array of capillary tubes. Other embodiments include vacuum use attached to the capillary tubes to increase the speed of detection.
Type:
Grant
Filed:
October 11, 2002
Date of Patent:
December 21, 2004
Assignee:
COMBISEP
Inventors:
Jeremy R. Kenseth, Ho-Ming Pang, Roy F. Strasburg
Abstract: A multiplexed, absorbance-based electrophoresis system for analyzing multiple samples simultaneously without use of a mask or slit comprising a light source, a planar array of capillary tubes and a detector positioned off-axis with the light source and positioned on-axis with and parallel to the planar array of capillary tubes. Other embodiments include vacuum use attached to the capillary tubes to increase the speed of detection.
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