Patents Assigned to Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA)
  • Patent number: 11402307
    Abstract: A method for concentrating at least one analyte including the following steps: preparing a first phase including at least one analyte; depositing a drop of the first phase on a substrate; depositing on the drop of first phase a drop of a second liquid phase including at least one surfactant, the second phase being non-miscible with the first phase; evaporating the drop of the second phase; and evaporating the drop of the first phase. Also relates to a method for detecting at least one analyte using the concentration method; and a system using the detection method.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: August 2, 2022
    Assignee: COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (CEA)
    Inventors: Florent Malloggi, Kiarach Mesbah, Sarah Bregant
  • Publication number: 20220233673
    Abstract: A method of producing a monomer of a Shiga toxin B-subunit (STxB) protein or of a variant thereof by peptide chemical synthesis, as well as to a method of producing a pentamer of the STxB protein or of the variant thereof. The methods are particularly advantageous as they overcome major issues typically observed in peptide chemical synthesis, including solubility and purity issues.
    Type: Application
    Filed: June 4, 2020
    Publication date: July 28, 2022
    Applicants: INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), COMMISSARIAT Á L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (CEA), APHP (ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS), UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Anne BILLET, Frédéric SCHMIDT, Ludger JOHANNES, Denis SERVENT, Gilles MOURIER, Éric TARTOUR, Michael KAY, James M. FULCHER
  • Publication number: 20220053766
    Abstract: A process for preparing a biocidal, bactericidal and/or bacteriostatic material including the preparation of a polymer precursor solution that has (a) at least one monomer A having a porphyrin group and at least one radical polymerizable function, (b) at least one radical polymerizable monomer B, a photoinitiator, and (c) at least one of the monomers chosen from a monomer C having a quaternary amine and a radical polymerizable function; and/or a monomer D having copper and a radical polymerizable function. Also, the material obtainable by the process and its uses.
    Type: Application
    Filed: December 19, 2019
    Publication date: February 24, 2022
    Applicants: COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (CEA), CONSERVATOIRE NATIONAL DES ARTS ET METIERS (CNAM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS).
    Inventors: Thomas BERTHELOT, Céline GOULARD-HUET, Fanny HAUQUIER
  • Publication number: 20210267412
    Abstract: Air filtration, in particular in cooking appliances, such as for example deep fryers. In particular, an odorless lid suitable for any container that allows odors or volatile compounds to escape and more particularly for any food cooking appliance, the odorless lid comprises a filtering material of particles having a core-shell structure, wherein the activated carbon core is surrounded by a shell of a mesoporous sol-gel material based on functionalized or nonfunctionalized silica.
    Type: Application
    Filed: July 12, 2019
    Publication date: September 2, 2021
    Applicants: ETHERA, COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (CEA), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Marie-Pierre SOM, Thu-Hoa TRAN-THI, Christophe THERON, William BAMOGO, Trung-Hieu NGUYEN
  • Patent number: 11040000
    Abstract: For the cosmetic field, omniphobic cosmetic pigments under the form of a core shell structure: the core is or includes of a metal oxide on which is adsorbed poly(?-(1?4)-D-glucosamine) chains; the chains being acetylated, or partially or totally deacetylated. Also, the process for manufacturing the omniphobic cosmetic pigments, including: (i) preparing an acidic aqueous solution including metal oxide particles and a poly (?-(1?4)-D-glucosamine), the poly (?-(1?4)-D-glucosamine) being acetylated, or partially or totally deacetylated; and (ii) increasing the pH until 12, of the solution obtained at step (i) in order to obtain the adsorption of said poly (?-(1?4)-D-glucosamine on the metal oxide particles and the precipitation of the resulting metal oxide particles coated with the poly (?-(1?4)-D-glucosamine.
    Type: Grant
    Filed: November 15, 2019
    Date of Patent: June 22, 2021
    Assignees: COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (CEA), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, MIYOSHI EUROPE S.A.S.
    Inventors: Patrick Guenoun, Christophe Fajolles, Tetsuya Takahashi, Stephane Nicolas, Pauline Bosmet, Sébastien Gougeon
  • Publication number: 20200163916
    Abstract: Probenecid or a pharmaceutical acceptable salt thereof for use in the treatment of a neurological disorder in a subject in need thereof, wherein administration of probenecid or a pharmaceutical acceptable salt thereof controls clinical or electrographic seizures in the subject. Preferably, the neurological disorder is an epileptic disease, disorder or condition.
    Type: Application
    Filed: July 13, 2018
    Publication date: May 28, 2020
    Applicants: PARIS SCIENCES ET LETTRES - QUARTIER LATIN, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), SORBONNE UNIVERSITÉ, APHP (ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS), COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (CEA), UNIVERSITE DE PARIS
    Inventors: Nathalie ROUACH, Eléna DOSSI, Gilles HUBERFELD
  • Publication number: 20200155441
    Abstract: For the cosmetic field, omniphobic cosmetic pigments under the form of a core shell structure: the core is or includes of a metal oxide on which is adsorbed poly(?-(1?4)-D-glucosamine) chains; the chains being acetylated, or partially or totally deacetylated. Also, the process for manufacturing the omniphobic cosmetic pigments, including: (i) preparing an acidic aqueous solution including metal oxide particles and a poly (?-(1?4)-D-glucosamine), the poly (?-(1?4)-D-glucosamine) being acetylated, or partially or totally deacetylated; and (ii) increasing the pH until 12, of the solution obtained at step (i) in order to obtain the adsorption of said poly (?-(1?4)-D-glucosamine on the metal oxide particles and the precipitation of the resulting metal oxide particles coated with the poly (?-(1?4)-D-glucosamine.
    Type: Application
    Filed: November 15, 2019
    Publication date: May 21, 2020
    Applicants: COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (CEA), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, MIYOSHI EUROPE S.A.S.
    Inventors: Patrick GUENOUN, Christophe FAJOLLES, Tetsuya TAKAHASHI, Stephane NICOLAS, Pauline BOSMET, Sébastien GOUGEON
  • Publication number: 20200041393
    Abstract: A method for concentrating at least one analyte including the following steps: preparing a first phase including at least one analyte; depositing a drop of the first phase on a substrate; depositing on the drop of first phase a drop of a second liquid phase including at least one surfactant, the second phase being non-miscible with the first phase; evaporating the drop of the second phase; and evaporating the drop of the first phase. Also relates to a method for detecting at least one analyte using the concentration method; and a system using the detection method.
    Type: Application
    Filed: October 6, 2017
    Publication date: February 6, 2020
    Applicant: COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (CEA)
    Inventors: Florent MALLOGGI, Kiarach MESBAH, Sarah BREGANT
  • Patent number: 9623015
    Abstract: Provided are methods for eliminating hematologic cancer stem cells in vivo, and thus preventing cancer relapse. The methods comprise a Signal Transducer and Activator of Transcription 5 (STAT5) antagonist (e.g., a PPAR? agonist) after the patient has had ana initial course of treatment with an anti-cancer agent (e.g., a TKI), to eliminate residual cancer stem cells which cause relapse.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: April 18, 2017
    Assignee: Commissariat à L'Energie Atomique et aux Energies Alternatives (CEA)
    Inventors: Stéphane Prost, Marek Kirszenbaum, Mikael Le Dantec, Philippe Rousselot, Philippe Leboulch
  • Publication number: 20150174298
    Abstract: An implantable material has at least one external surface grafted with a film including carboxylate and sulfonate functions wherein the film is simultaneously synthesized and grafted directly on the external surface by radical reaction of a source of carboxylate functions, the source being either polymerizable or chemisorbable and polymerizable and a source of sulfonate functions, the source being either polymerizable or chemisorbable and polymerizable. A process for simultaneously synthesizing and grafting a film directly onto at least one external surface of an implantable material, and the use of a grafted implantable material for the manufacture of an antiproliferative and/or antibacterial implantable medical device are also described.
    Type: Application
    Filed: June 14, 2013
    Publication date: June 25, 2015
    Applicants: BIOWINTECH, COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVE (CEA)
    Inventors: Alexandre Brouzes, Laurent David, Guy Deniau, Maxime Oudin
  • Patent number: 8513042
    Abstract: A method of forming an electromechanical transducer device comprises forming on a fixed structure a movable structure and an actuating structure of the electromechanical transducer device, wherein the movable structure is arranged in operation of the electromechanical transducer device to be movable in relation to the fixed structure in response to actuation of the actuating structure. The method further comprises providing a stress trimming layer on at least part of the movable structure, after providing the stress trimming layer, releasing the movable structure from the fixed structure to provide a released electromechanical transducer device, and after releasing the movable structure changing stress in the stress trimming layer of the released electromechanical transducer device such that the movable structure is deflected a predetermined amount relative to the fixed structure when the electromechanical transducer device is in an off state.
    Type: Grant
    Filed: June 15, 2010
    Date of Patent: August 20, 2013
    Assignees: Freescale Semiconductor, Inc., Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA)
    Inventors: Francois Perruchot, Lianjun Liu, Sergio Pacheco, Emmanuel Defay, Patrice Rey
  • Patent number: 8445978
    Abstract: A micro or nano electromechanical transducer device formed on a semiconductor substrate comprises a movable structure which is arranged to be movable in response to actuation of an actuating structure. The movable structure comprises a mechanical structure comprising at least one mechanical layer having a first thermal response characteristic and a first mechanical stress response characteristic, at least one layer of the actuating structure, the at least one layer having a second thermal response characteristic different to the first thermal response characteristic and a second mechanical stress response characteristic different to the first mechanical stress response characteristic, a first compensation layer having a third thermal response characteristic and a third mechanical stress characteristic, and a second compensation layer having a fourth thermal response characteristic and a fourth mechanical stress response characteristic.
    Type: Grant
    Filed: November 25, 2009
    Date of Patent: May 21, 2013
    Assignees: Freescale Semiconductor, Inc., Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA)
    Inventors: Francois Perruchot, Emmanuel Defay, Patrice Rey, Lianjun Liu, Sergio Pacheco