Abstract: The present invention relates to the field of medical diagnostics and more specifically, to identification of amniotic fluid.

Abstract: The present invention relates to the field of medical diagnostics and more specifically, to identification of amniotic fluid.

Abstract: The present invention provides a non-toxic diagnostic composition for intravaginal monitoring of vaginal infections. The present invention further provides a diagnostic article for intravaginal monitoring of vaginal infections with the article including an absorbent material for absorbing vaginal secretions and a composition suitable for identification of the pH or the buffer capacities associated with vaginal secretions. The diagnostic composition provides a visible indication of vaginal infections, such as bacterial vaginosis.

Abstract: A method for identifying physiological conditions associated with the pH or the buffer capacities of biological fluid secreted from a person, by providing a secretion-monitoring article of a body that includes an absorbent material for absorbing a biological fluid secreted from a person and an indicator system having a hydrophobic chemical composition that includes an indicator agent and an ion-balance reagent, at specific relative amounts. Optionally, a competitive agent for establishing a pre-set threshold of an analyte of interest in a tested bodily fluid, is added to the indicator system, wherein the indicator reagent being charged oppositely to the analyte of interest and the competitive reagent having the same charge as the indicator reagent.

Abstract: A method for identifying physiological conditions associated with a biological fluid secreted from a person, by providing a secretion-monitoring article of a body that includes an absorbent material for absorbing a biological fluid secreted from a person and an indicator system having a hydrophobic chemical composition that includes an indicator agent and an ion-balance reagent of a quaternary amine; wearing the article in a position to receive the biological fluid secreted from the person; and visualizing the indicator system for an indication of physiological conditions associated with the biological fluid, which indication is typically a measurement of the pH or buffer capacities of the fluid and is stable for at least 48 hours.

Abstract: A method for identifying physiological conditions associated with the pH or the buffer capacities of biological fluid secreted from a person, which comprises providing a secretion-monitoring article comprising a body that includes an absorbent material for absorbing a biological fluid secreted from a person and an indicator system having a hydrophobic chemical composition comprising an indicator agent and an ion-balance reagent, wherein the ion-balance reagent is a quaternary amine; wearing the article in a position to receive the biological fluid secreted from the person; visualizing the indicator system for an indication of physiological conditions associated with the pH or the buffer capacities of the biological fluid, which indication is stable for at least 48 hours.

Abstract: A secretion-monitoring article for identifying a secreted biological fluid. The article includes a body with an absorbent material for absorbing a biological fluid secreted from a person and an indicator system. The indicator system includes an indicator agent and an ion-balance reagent, wherein the indicator system provides an indication of physiological conditions associated with the pH or the buffer capacities of the biological fluid, which indication is stable for at least 48 and preferably at least 72 hours. The article can be embodied as a swab, gauze, shield, hygienic napkin, diaper or interlabial absorbent structure and can be used to indicate the presence of amniotic fluid, or secretions associated with bacterial vaginosis without giving a false positive result upon exposure to urine or after drying.

Abstract: A secretion-monitoring article for identifying a secreted biological fluid having a body with an absorbent material and least one pH determining member and a reagent associated with the absorbent material is disclosed. The article can be embodied as a swab, gauze, panty shield, hygienic napkin, diaper or interlabial absorbent structure and can be used to indicate the presence of amniotic fluid, or secretions associated with bacterial, parasite, fungal, or yeast infections without giving a false positive result upon exposure to urine. The present invention also teaches a pH indicator mixture and method of attaching the indicator to a substrate for use alone or integrated in an absorbent body and further teaches a method for monitoring the health condition of a person using the secretion-monitoring article.

Abstract: A kit for generating a biological sample from a discharge emitted from a portion of a body includes an absorbent pad for deploying adjacent to the portion of the body and a portable device for preserving and/or pre-processing the sample. The pad includes a sampling membrane configured to retain at least one biological material. The portable device has a housing formed from a base portion and lid portion which together define a sealable sample chamber for receiving the sampling membrane. An injector device is configured to be activated by closing of the lid portion to inject sample extracting solution into the sample chamber.

Abstract: An indicator system including two pH sensitive indicators and a reagent is disclosed. The indicator system can be integrated into a number of products such as sanitary napkins or panty shields and thus can indicate the presence of amniotic fluid or secretions associated with vaginosis without giving a false positive result upon exposure to urine.

Abstract: A secretion-monitoring article for identifying a secreted biological fluid having a body with an absorbent material and least one pH determining member and a reagent associated with the absorbent material is disclosed. The article can be embodied as a swab, gauze, panty shield, hygienic napkin, diaper or interlabial absorbent structure and can be used to indicate the presence of amniotic fluid, or secretions associated with bacterial, parasite, fungal, or yeast infections without giving a false positive result upon exposure to urine. The present invention also teaches a pH indicator mixture and method of attaching the indicator to a substrate for use alone or integrated in an absorbent body and further teaches a method for monitoring the health condition of a person using the secretion-monitoring article.

Abstract: A pH sensor for the visual or optical indication of the pH of a sample. The pH sensor includes a hydrophilic, optionally intrinsically charged or neutral, synthetic membrane and at least one pH indicator dye immobilized thereto, so as to prevent appreciated bleeding of the at least one indicator dye from the synthetic membrane upon immersion in an aqueous liquid.

Abstract: A kit for generating a biological sample from a discharge emitted from a portion of a body includes an absorbent pad for deploying adjacent to the portion of the body and a portable device for preserving and/or pre-processing the sample. The pad includes a sampling membrane configured to retain at least one biological material. The portable device has a housing formed from a base portion and lid portion which together define a sealable sample chamber for receiving the sampling membrane. An injector device is configured to be activated by closing of the lid portion to inject sample extracting solution into the sample chamber.

Abstract: An indicator system including two pH sensitive indicators and a reagent is disclosed. The indicator system can be integrated into a number of products such as sanitary napkins or panty shields and thus can indicate the presence of amniotic fluid or secretions associated with vaginosis without giving a false positive result upon exposure to urine.

Abstract: A method of analysis of vaginal secretions collected in an absorbent pad is disclosed. The method is effected by implementing the steps of (a) using an absorbent pad for collecting the vaginal secretions, the absorbent pad including an inner membrane for absorbing at least a portion of the secretion, the inner membrane being embedded among layers of the absorbent pad, and an external, viewable membrane including a color indicator for indicating a location of secretions absorbed by the absorbent pad according to at least one parameter being indicative of a pathological state; and (b) if the pathological state is indicated, biochemically analyzing the inner membrane at a location respective to the location of secretions absorbed by the absorbent pad for further characterizing the pathological state.