Patents Assigned to Commonwealth Biotechnologies, Inc.
  • Adsorption and removal of endotoxin from physiological fluids using cationic helix peptides
    Patent number: 6756206
    Abstract: The present invention provides endotoxin-binding peptides which are useful in the treatment and prevention of sepsis. The present invention further provides a method for treating or preventing sepsis comprising administration of the compounds of the present invention.
    Type: Grant
    Filed: February 14, 2001
    Date of Patent: June 29, 2004
    Assignee: Commonwealth Biotechnologies, Inc.
    Inventors: Robert B. Harris, Russell L. Wolz, Gabriella Wolz
  • Heparin binding peptides
    Patent number: 6200955
    Abstract: The present invention provides heparin antagonist peptides. The heparin-binding peptides of the present invention specifically neutralize heparin's conventional anticoagulant properties without causing deleterious hemodynamic side-effects or exacerbation of the proliferative vascular response to injury. More specifically, the heparin-binding compounds of the present invention are short-duration drugs to be used in elective or emergency situations which can safely and specifically neutralize heparin's conventional anticoagulant properties without causing deleterious hemodynamic side-effects or exacerbation of the proliferative vascular response to injury.
    Type: Grant
    Filed: October 6, 1998
    Date of Patent: March 13, 2001
    Assignee: Commonwealth Biotechnologies, Inc.
    Inventors: Robert B. Harris, Michael Sobel
  • Automated DNA Sequencer loading dye which contains a lane tracking aid
    Patent number: 6110683
    Abstract: The present invention provides a reagent which can be used as a marker to identify individual lanes on an electrophoresis gel which is run on an Automated DNA Sequencer. This reagent is may be included in the loading dye for samples in DNA sequencing, DNA fragment analysis, or linkage mapping analysis. Inclusion of the reagent aids in the identification of the lane in which each sample is individually loaded on the acrylamide gel, such that the data read from each lane by the instrument is correctly applied to the appropriate sample.
    Type: Grant
    Filed: January 29, 1999
    Date of Patent: August 29, 2000
    Assignee: Commonwealth Biotechnologies, Inc.
    Inventors: Thomas R. Reynolds, Gregory A. Meyers, Gregory A. Buck, Joshua Rameaka
  • Heparin-binding peptides
    Patent number: 5877153
    Abstract: The present invention provides heparin antagonist peptides. The heparin-binding peptides of the present invention specifically neutralize heparin's conventional anticoagulant properties without causing deleterious hemodynamic side-effects or exacerbation of the proliferative vascular response to injury. More specifically, the heparin-binding compounds of the present invention are short-duration drugs to be used in elective or emergency situations which can safely and specifically neutralize heparin's conventional anticoagulant properties without causing deleterious hemodynamic side-effects or exacerbation of the proliferative vascular response to injury.
    Type: Grant
    Filed: June 11, 1996
    Date of Patent: March 2, 1999
    Assignee: Commonwealth Biotechnologies Inc.
    Inventors: Robert B. Harris, Michael Sobel