Patents Assigned to Commonwealth Scientific and Industrial Research Organization
  • Publication number: 20040071690
    Abstract: This invention provides polyvalent or polyspecific protein complexes, comprising three or more polypeptides which associate to form three or more functional target-binding regions (TBRs), and in which each individual polypeptide comprises two or more immunoglobulin-like domains which are covalently joined together, such that two Ig-like domains in a single polypeptide do not associate with each other to form a TBR. By using a linker peptide of fewer than three amino acid residues the immunoglobulin-like domains of the individual polypeptides are prevented from associating, so that complex formation between polypeptides is favoured. Preferably the polyvalent or polyspecific protein is a trimer or tetramer. The proteins of the invention have specificities which may be the same or different, and are suitable for use as therapeutic, diagnostic or imaging agents.
    Type: Application
    Filed: February 19, 2003
    Publication date: April 15, 2004
    Applicant: COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION
    Inventors: Peter John Hudson, Alex Andrew Kortt, Robert Alexander Irving, John Leslie Atwell
  • Patent number: 6689354
    Abstract: A method of improving the productivity of a ruminant animal comprising administering to said animal an amount of an immunogenic preparation effective to invoke an immune response to at least one rumen protozoan, such that the immune response invoked at least reduces and preferably totally removes the activity of the at least one rumen protozoan. The invention also provides novel immunogenic preparations which may be used in the method of the invention.
    Type: Grant
    Filed: February 5, 1999
    Date of Patent: February 10, 2004
    Assignee: Commonwealth Scientific and Industrial Research Organization
    Inventors: Suzanne Kay Baker, Gnanapragasam Gnanasampanthan, Douglas Barrie Purser, Ronald Milton Hoskinson
  • Patent number: 6682764
    Abstract: A method for the microwave irradiation of a vegetable to cook the same and to brown the exterior thereof includes the steps of applying a microwave activated browning agent to the surface of the vegetable; prior to irradiation, positioning a shielding material adjacent to the vegetable in a location such that, during irradiation, adjacent portions of the vegetable are shielded from microwave radiation; and irradiating the vegetable with microwave radiation to cook and brown the same.
    Type: Grant
    Filed: November 16, 1999
    Date of Patent: January 27, 2004
    Assignee: Commonwealth Scientific and Industrial Research Organization
    Inventors: Stephen Morris, Barbara Stephens
  • Publication number: 20040007763
    Abstract: A semiconductor wafer composite is used as a basis for fabricating semiconductor chips, especially compound semiconductor devices. The semiconductor wafer composite advantageously comprises a metallic substrate 210 and multiple semiconductor tiles 220 bonded to the surface of the metallic substrate 210. The semiconductor wafer composite is effectively used as a single large semiconductor wafer for volume fabrication, and can be used to fabricate semiconductor devices in a similar manner.
    Type: Application
    Filed: March 13, 2003
    Publication date: January 15, 2004
    Applicant: Commonwealth Scientific and Industrial Research Organization Campbell, Australia
    Inventor: Shaun Joseph Cunningham
  • Patent number: 6653407
    Abstract: The present invention is directed to a process for forming star shaped microgels which include a core of crosslinked polymer and multiplicity of substantially linear polymeric arms of macromonomers attached to the core. The process includes polymerizing monoethylenically unsaturated monomers in the presence of a chain transfer agent to form macromonomers each having a terminal polymerizable ethylenically unsaturated group and then polymerizing, in presence of the macromonomers, the monoethylenically unsaturated monomers and multi-olefinic crosslinking monomers. The microgels of the present invention can be used as rheology control agents in waterborne and solvent-borne coatings and in adhesives and cosmetics.
    Type: Grant
    Filed: October 3, 2001
    Date of Patent: November 25, 2003
    Assignees: E. I. du Pont de Nemours and Company, Commonwealth Scientific and Industrial Research Organization, University of Melburne
    Inventors: Charles T. Berge, Michael Fryd, Jeffrey W. Johnson, Graeme Moad, Ezio Rizzardo, Christopher Scopazzi, San Hoa Thang
  • Patent number: 6646055
    Abstract: A process for preparing microgel(s) that uses a wide range of activatable prepolymers. In the process, a polymer composition of crosslinked component A and soluble components B and C is formed from mono-olefinic and multi-olefinic monomers in the presence of catalyst and initiator. The process comprises: I) introducing mono-olefinic monomer, catalyst, and initiator into a reactor in the absence of multi-olefinic monomer and producing an activatable prepolymer, component B; II) contacting the product of I) with multi-olefinic monomer to produce components A and C, optionally in the presence of additional initiator; also optionally in the presence of additional mono-olefinic monomer and initiator. The ratio of components A/(B+C) can be controlled by varying the mole ratio of The Component B/multi-olefinic monomer from 0.05/1 up to 5/1, by decreasing the mole ratio to increase the ratio of A/(B+C), and increasing the mole ratio to decrease the ratio of A/(B+C).
    Type: Grant
    Filed: October 3, 2001
    Date of Patent: November 11, 2003
    Assignees: E. I. du Pont de Nemours and Company, Commonwealth Scientific and Industrial Research Organization, University of Melburne
    Inventors: Charles T. Berge, Michael Fryd, Jeffrey W. Johnson, Graeme Moad, Ezio Rizzardo, Christopher Scopazzi, San Hoa Thang
  • Patent number: 6642318
    Abstract: A free radical polymerization process suitable for synthesizing polymers is disclosed. The process utilizes novel sulfur based chain transfer agents and is widely compatible over a range of monomers and reaction conditions. Novel polymers having low polydispersity and predictably specific polymer architecture and molecular weight are produced by the process. The polymers produced by the process are suitable for use as binders in automotive OEM and refinish coatings.
    Type: Grant
    Filed: June 16, 2000
    Date of Patent: November 4, 2003
    Assignees: E. I. du Pont de Nemours and Company, Commonwealth Scientific and Industrial Research Organization
    Inventors: John Chiefari, Roshan Tyrrel Mayadunne, Graeme Moad, Ezio Rizzardo, San Hoa Thang
  • Patent number: 6637366
    Abstract: A composition and method for controlling scarabs, especially lawn scarabs, utilising certain strains of the entomopathogenic nematode species, Heterorhabditis zealandica are disclosed. The nematode strains used in the composition and method generally have an LD50 value of less than 300 IJ as measured by pot assays against final instar scarab larvae.
    Type: Grant
    Filed: October 1, 2001
    Date of Patent: October 28, 2003
    Assignee: Commonwealth Scientific and Industrial Research Organization
    Inventors: Robin Anthony Bedding, Simone Daniella Clark, Karen Louise Butler, Jacqueline Louise Vella, Felice Driver
  • Patent number: 6629413
    Abstract: A closed cycle thermodynamic apparatus (10) is provided for powering a combustion machine. The apparatus (10) has a compressor (12) for compressing a working medium from a reservoir (14) at temperature T1. The temperature of the working medium increases during compression and reaches temperature T2 when leaving the compressor (12). It is then expanded in an expander (16) for turning the machine. In this manner mechanical work is extracted from the working medium. The apparatus (10) has a first heat exchanger (18) and a second heat exchanger (20) connected to the compressor (12) and the expander (16) in a closed cycle. It also has a burner (22) and a third heat exchanger (24). Air, as a Heat transfer medium, at ambient temperature T5 is induced into the second exchanger (20) to cool the working medium by receiving heat therefrom. The temperature of the working medium decreases from T4 to T1 before entering the compressor (12) for repeating the cycle.
    Type: Grant
    Filed: May 14, 2002
    Date of Patent: October 7, 2003
    Assignee: The Commonwealth of Australia Commonwealth Scientific and Industrial Research Organization
    Inventors: Michael Noel Wendt, Patrick Joseph Glynn
  • Patent number: 6624261
    Abstract: This invention relates to a process for controlling the architecture of copolymers of at least two unsaturated monomers, made by free-radical polymerization in the presence of a cobalt-containing chain transfer agent, including the control of molecular weight, degree of branching and vinyl end group termination, by varying at least one of the variables of molar ratio of monomers, their relative chain transfer constants, polymerization temperature and degree of conversion and amount of cobalt chain transfer agent; and polymers made thereby.
    Type: Grant
    Filed: August 19, 1998
    Date of Patent: September 23, 2003
    Assignees: E. I. du Pont Nemours and Company, Commonwealth Scientific and Industrial Research Organization
    Inventors: Graeme Moad, Ezio Rizzardo, Catherine Louise Moad, Steven Dale Ittel, Lech Wilczek, Alexei A. Gridnev
  • Patent number: 6562398
    Abstract: A method of ionically and/or electrically insulating a surface of a material is provided. The method comprises attaching to the surface a self-assembling monolayer membrane. The membrane comprises self-assembling molecules that comprise hydrocarbon chains having a length of 3 to 60 carbons. The self-assembling molecules are selected such that the membrane is liquid crystalline.
    Type: Grant
    Filed: January 26, 2001
    Date of Patent: May 13, 2003
    Assignee: Commonwealth Scientific and Industrial Research Organization
    Inventors: Vijoleta Braach-Maksvytis, Burkhard Raguse
  • Patent number: 6495643
    Abstract: The invention relates to compounds of the formulae: processes for their preparation, polymers, co-polymers or block co-polymers containing them or their use as monomers or co-monomers in free radical polymerization and in the manufacture of adhesives, dental composites or optical lenses.
    Type: Grant
    Filed: October 2, 2001
    Date of Patent: December 17, 2002
    Assignee: Commonwealth Scientific and Industrial Research Organization
    Inventors: Richard Alexander Evans, Ezio Rizzardo, Graeme Moad
  • Patent number: 6475390
    Abstract: A separation process is described for separation of a nutrient from divalent ions of an aqueous solution. The aqueous solution is contacted with an ion exchange resin that includes monovalent ions until the concentration of divalent ions in the aqueous solution has been depleted and an eluate is collected. The eluate is then subjected to a process, preferably a nanofiltration membrane process, capable of separating monovalent ions to obtain a permeate fraction including monovalent ions and a retentate fraction including the nutrient. The retentate fraction is then separated into fractions with at least one fraction including a major portion of the nutrient. The ion exchange resin is then regenerated by contacting it with a solution including the permeate fraction until a major portion of the divalent ions have been replaced by monovalent ions.
    Type: Grant
    Filed: April 14, 2000
    Date of Patent: November 5, 2002
    Assignees: University of Western Sydney, Commonwealth Scientific and Industrial Research Organization, Dairy Research and Development Corporation
    Inventors: Rosalie Joyce Durham, James Arthur Hourigan, Robert Walter Sleigh, Robert Leonard Johnson
  • Patent number: 6448433
    Abstract: The invention relates to a process for the preparation of organic boronic acid derivatives involving the reaction of an organic compound with diboronic acid in the presence of a Group 8-11 metal catalyst.
    Type: Grant
    Filed: May 10, 2000
    Date of Patent: September 10, 2002
    Assignee: Commonwealth Scientific and Industrial Research Organization
    Inventors: Sebastian Mario Marcuccio, Mary Rodopoulos, Helmut Weigold
  • Patent number: 6423885
    Abstract: Methods are provided for reducing the phenotypic expression of a nucleic acid of interest in plant cells, by providing aberrant, preferably unpolyadenylated, target-specific RNA to the nucleus of the host cell. Preferably, the unpolyadenylated target-specific RNA is provided by transcription of a chimeric gene comprising a promoter, a DNA region encoding the target-specific RNA, a self-splicing ribozyme and a DNA region involved in 3′ end formation and polyadenylation.
    Type: Grant
    Filed: August 13, 1999
    Date of Patent: July 23, 2002
    Assignee: Commonwealth Scientific and Industrial Research Organization (CSIRO)
    Inventors: Peter Michael Waterhouse, Ming-Bo Wang
  • Patent number: 6407310
    Abstract: Third stage juvenile (J3) entomopathogenic nematodes are prepared for storage by being induced into a state of cryptobiosis. The induction of cryptobiosis is effected by mixing an aqueous cream of the J3 nematodes with anhydrous, small particles (average maximum dimension less than 300 &mgr;m) of non-fibrous cellulose. The proportions of the aqueous cream and non-fibrous cellulose particles are such that, after equilibration, the mixture has a water activity in the range 0.80 to 0.995. Preferably an anti-fungal agent is included in the aqueous cream. To store the cryptobiotic J3 nematodes, the mixture is preferably kept in a container, fitted with an attachment which maintains the water activity in the container at a required value. The attachment includes a rigid tube that connects the interior of the container with a chamber that is vented to ambient atmosphere by small apparatus.
    Type: Grant
    Filed: March 28, 2001
    Date of Patent: June 18, 2002
    Assignee: The Commonwealth of Australia Commonwealth Scientific and Industrial Research Organization
    Inventors: Robin Anthony Bedding, Simone Daniela Clark, Michael James Lacey, Karen Louise Butler
  • Patent number: 6391639
    Abstract: The invention provides plant and viral promoters that can be used to confer high-level gene expression on transgenic plants. Representative promoters can be isolated from the genome of Australian banana-infecting badnaviruses from cultivars Mysore, Williams and Goldfinger. The invention further provides construct which include the disclosed promoters operatively linked to a coding sequence. Still further provided are a method of expressing the product of a gene in a plant cell, plant cells having DNA constructs within their genomes, and plants comprising the transgenic cells.
    Type: Grant
    Filed: April 17, 2000
    Date of Patent: May 21, 2002
    Assignee: Commonwealth Scientific and Industrial Research Organization
    Inventors: Peer Martin Philipp Schenk, László Sagi, Serge Remy, Rony Leon Swennen, Ralf Georg Dietzgen, Andrew David William Geering, Lee Anne McMichael, John Edwin Thomas, Christopher Peter Leslie Grof, Adrian Ross Elliott
  • Patent number: 6381883
    Abstract: A method and apparatus for continuously pressure decatising a fabric include a rotatable drum (12) around which an endless belt (15) is arranged to travel for conveying a fabric (19) (and optionally a moisture laden textile (20)) between the facing surfaces of the belt (15) and the drum (12). The drum (12) is heated and fabric (19) is pressed between the belt and the drum as it is conveyed through the apparatus. The fabric (19) is subjected to pressurized saturated steam, which may be generated by evaporation of the moisture in textile (20) when it contacts the heated drum, as it is pressed. Various options other than use of a moisture laden textile (20) for supplying the steam are disclosed. The invention involves enclosing the drum in a pressure vessel (14) within which a compressed air atmosphere at ambient temperature is maintained.
    Type: Grant
    Filed: April 16, 1999
    Date of Patent: May 7, 2002
    Assignee: The Commonwealth of Australia Commonwealth Scientific and Industrial Research Organization
    Inventors: Cuong Viet Le, Nhan Gia Ly, Peter William Chudleigh, David Henry Tester, David Graham Phillips
  • Patent number: 6376626
    Abstract: A free-radical polymerization process for making macromonomers having the structure: comprising contacting: (a) CH2═CHY; (b) optionally, CH2═CXB; and (c) free-radicals, produced from a free-radical source; in which B, U, X, Y, Z, m, n and p are defined in the text; macromonomer quality being controlled by adjusting one or more of the following variables: molar ratios of a, b and c; temperature; monomer concentration; and conversion.
    Type: Grant
    Filed: October 19, 1999
    Date of Patent: April 23, 2002
    Assignee: Commonwealth Scientific and Industrial Research Organization
    Inventors: John Chiefari, Graeme Moad, Ezio Rizzardo, Alexei A. Gridnev
  • Patent number: 6355718
    Abstract: A process for preparing microgel(s) that uses a wide range of activatable prepolymers; in the process, a polymer composition of crosslinked component A and soluble components B and C is formed from mono-olefinic and multi-olefinic monomers in the presence of catalyst and initiator; the process comprises: I) introducing mono-olefinic monomer, catalyst, and initiator into a reactor in the absence of multi-olefinic monomer and producing an activatable prepolymer, component B; II) contacting the product of I) with multi-olefinic monomer to produce components A and C, optionally in the presence of additional initiator; also optionally in the presence of additional mono-olefinic monomer and initiator; the ratio of components A/(B+C) can be controlled by varying the mole ratio of Component B/ multi-olefinic monomer from 0.05/1 up to 5/1, by decreasing the mole ratio to increase the ratio of A/(B+C), and increasing the mole ratio to decrease the ratio of A/(B+C).
    Type: Grant
    Filed: July 9, 1999
    Date of Patent: March 12, 2002
    Assignees: E. I. du Pont de Nemours and Company, Commonwealth Scientific and Industrial Research Organization, University of Melbourne, Australia
    Inventors: Charles T. Berge, Michael Fryd, Jeffrey W. Johnson, Graeme Moad, Ezio Rizzardo, Christopher Scopazzi, San Hoa Thang