Patents Assigned to Commonwealth Scientific and Research Organization
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Patent number: 7767792Abstract: The present invention relates generally to growth factor receptor epitope peptides, particularly EGF family receptor epitope peptides. The invention also relates to the use of the receptor peptides in generating antibodies which have anti-tumor or anti-cancer activity or in stimulating an immunological response. The invention further relates to antibodies specifically directed against the receptor peptides. Methods for generating an immune response and for treatment of tumors and cancer are also provided.Type: GrantFiled: February 17, 2005Date of Patent: August 3, 2010Assignees: Ludwig Institute for Cancer Research Ltd., Commonwealth Scientific & Industrial Research Organization, Massachusetts Institute for TechnologyInventors: Terrance Grant Johns, Andrew Mark Scott, Antony Wilks Burgess, Lloyd J. Old, Timothy E. Adams, K. Dane Wittrup, Ginger Chao, Peter Anthony Hoyne
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Patent number: 6991823Abstract: A calcium and/or nutritional mineral fortified milk or milk powder product utilizes pyrophosphates or orthophosphates in combination with maintenance of pH within the range of 6.5 to 7.5 to render the milk heat stable. Additional calcium and/or nutritional mineral is added in soluble form either before or after the phosphate addition. The preferred orthophosphates are one or more of monosodium dihydrogen orthophosphate, disodium hydrogen orthophosphate, trisodium orthophosphate, monopotassium dihydrogen orthophosphate, dipotassium hydrogen orthophosphate and tri potassium orthophosphate. Addition of an alkaline agent to adjust the pH is not needed if an appropriate mix of orthophosphates is used. The milk products or milk products recombined from milk powders are heat stable and do not have the problems of translucency, gritty mouth feel or sedimentation which can be associated with other stabilized fortified milks.Type: GrantFiled: March 30, 2001Date of Patent: January 31, 2006Assignees: Commonwealth Scientific & Industrial Research Organization Centre, Dairy Research & Development Corp.Inventors: Mary Ann Augustin, Roderick Patterson Winfield Williams
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Patent number: 6878527Abstract: A method for producing a modified glutenin or seed-storage protein, the method comprising adding to the protein an exogenous amino acid domain which confers to the modified protein the ability to bind a ligand or other macromolecule. Wherein the modified protein has an ability to incorporate into gluten, modified glutenin or seed-storage proteins, and uses thereof.Type: GrantFiled: July 12, 1999Date of Patent: April 12, 2005Assignees: Commonwealth Scientific & Industrial Research Organization, Biogemma S.A.S.Inventors: Rudi Appels, Matthew Morell, Frank Bekes, Laszlo Tamas
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Patent number: 6342969Abstract: A pixellated diffractive device includes a multiplicity of pixels (12,22) in turn divided into multiple sub-pixels (13,23). The device is related to one or more pixellated diffraction surface structures which when illuminated generate respective corresponding optically variable images. The sub-pixels (13,23) of each pixel of the diffractive device include diffractive elements (13a,23a) arranged in one or more groups, the diffractive elements of each group matching diffractive elements of a corresponding single pixel of the respective pixellated diffraction surface structures. In each pixel of the device the diffractive elements (13a,23a) of the or each said group are intermixed with other sub-pixels and cooperatively contribute a single element of the corresponding optically variable image which is generated on illumination of the diffractive device.Type: GrantFiled: February 11, 1999Date of Patent: January 29, 2002Assignee: Commonwealth Scientific/Industrial Research OrganizationInventor: Robert Arthur Lee
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Patent number: 6291620Abstract: Process for the synthesis of block polymers, homopolymers and copolymers of narrow polydispersity having formula (1) by contacting selected vinyl monomer(s), vinyl-terminated compound(s) and free radicals in which effective control of production of polymer is achieved by controlling the mole ratio of vinyl monomer(s), vinyl-terminated compound(s) and free radicals relative to one another; and polymers produced therebyType: GrantFiled: November 20, 1997Date of Patent: September 18, 2001Assignees: E. I. du Pont de Nemours and Company, Commonwealth Scientific Industrial Research OrganizationInventors: Graeme Moad, Catherine Louise Moad, Julia Krstina, Ezio Rizzardo, Thomas Robert Darling, Charles Thomas Berge
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Patent number: 6271340Abstract: This invention concerns the preparation of polymers of low polydispersity and/or controlled molecular weight and architecture employing living free radical polymerization initiated by an alkoxyamine initiator or nitroxide plus, optionally a free radical initiator, the polymer produced thereby; selected nitroxide and alkoxyamine initiators; and a process for making the initiators; the polymeric products being useful in protective coatings.Type: GrantFiled: November 5, 1999Date of Patent: August 7, 2001Assignees: E. I. du Pont de Nemours and Company, Commonwealth Scientific & Industrial Research OrganizationInventors: Albert G. Anderson, Alexei Gridnev, Graeme Moad, Ezio Rizzardo, San Hoa Thang
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Patent number: 5374678Abstract: A wood adhesive composition including an effective amount of a phenol-formaldehyde resin; and a modifying agent which agent renders the composition capable of bonding to a hard wood.Type: GrantFiled: January 15, 1993Date of Patent: December 20, 1994Assignees: Commonwealth Scientific & Industrial Research Organization, Huntsman Chemical Company Australia LimitedInventors: Peter J. Collins, Michael J. Delaney, Yoshikazu Yazaki
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Patent number: 5302149Abstract: A boning process and apparatus for separating meat and bone, particularly ribs, in an animal carcass. The spine (12) is restrained relative to the ribs (16) and which are moved in an arc (A) so as to dislocate the joints (17) and to sever connective tissue. This exposes the ribs (16) at the dislocated joints (17) and the exposed ends (16a) are moved along a line (B or C) to progressively extend the exposed portions (16a) so as to separate a major part of each rib (16) from tissues (20) remaining attached to the spine (12). Cuts (21, 22) are formed in the tissues adjacent to the spine (12) and adjacent to the joint (17) to assist in exposing the ribs (16).Type: GrantFiled: January 21, 1993Date of Patent: April 12, 1994Assignees: William John Witham, Commonwealth Scientific & Industrial Research Organization, Meat Research CorporationInventors: William J. Witham, Russel J. Rankin, Andrew M. Leiner, Darryl J. Heidke, Richard J. Gibbons, Edward G. Mills, Paul A. Green, Matthew Aqualini, John W. Buhot, Phillip R. Boyce, Andrew L. Finney
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Patent number: 5296420Abstract: A relatively dense composite refractory material which has reasonable strength and good thermal shock resistance comprises an alumina matrix material within which are dispersed particles of polycrystalline zirconia comprises from 1.0 to 40 percent by volume of the composite material. Each particle of zirconia is an agglomerate of microcrystals which are strongly bonded together. Due to the agglomerates of the bonding together of the microcrystals at their grain boundaries. The microcrystals contain no matrix material within their agglomerates, and exhibit strong thermal expansion anisotropy. They have a size such that cracks do not form spontaneously within the agglomerates during cooling from about 1600.degree. C. to room temperature. Typically the agglomerates have a mean diameter of from 10 to 15 micrometers, while the average diameter of the microcrystals in an agglomerate is from 1 to 2 micrometers.Type: GrantFiled: May 29, 1992Date of Patent: March 22, 1994Assignee: Commonwealth Scientific & Industrial Research OrganizationInventor: Ronald C. Garvie
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Patent number: 5195923Abstract: An apparatus for automatically processing an animal carcass (8). Suspension means (122, 123) suspends the carcass (8) in an inverted position with the spine inclined upwardly towards the neck (11) with the spine located beneath the carcass (8) and so that the diaphragm (119) is approximately vertical. A cutting assembly, (130) moves into the abdominal cavity adjacent to the diaphragm (119), and a cutting means (28) cuts the diaphragm (119) around the periphery. A brisket shearing means (21) cuts the brisket (20) with a shearing action along the brisket (20) from the abdomen and towards the neck end of the brisket (20). The reaction member (188) is pivotally movable relative to the brisket (20) about a rear end to generally follow the contours of the brisket (20).Type: GrantFiled: May 20, 1992Date of Patent: March 23, 1993Assignees: Commonwealth Scientific & Industrial Research Organization, Australian Meat & Live-Stock Research & Development CorporationInventors: Russel J. Rankin, David J. de Chastel, deceased, Graeme L. Wescombe, David T. Kerr, Phillip R. Boyce, Raymond M. White, Robert W. Tritchler, John W. Buhot
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Patent number: 5142918Abstract: An apparatus to measure the bending length and bending rigidity of a piece of fabric comprising a generally planar surface upon which the plate of fabric is moved. The surface terminates at one end with an edge over which a leading end of the fabric passes. An optical device defines a plane extending downwardly from the surface edge at approximately 41.5 degrees. The optical device detects when the plane is intersected by the leading end of the fabric when, after a sufficient length of the piece of fabric has passed beyond the surface edge to cause bending of the fabric piece, the leading edge of the fabric intersects the plane.Type: GrantFiled: August 15, 1990Date of Patent: September 1, 1992Assignee: Commonwealth Scientific & Industrial Research OrganizationInventors: Frank Scaysbrook, Nhan G. Ly
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Patent number: 5139457Abstract: An apparatus for automatically processing an animal carcass (8). Suspension means (122, 123) suspends the carcass (8) in an inverted position with the spine inclined upwardly towards the neck (11) with the spine located beneath the carcass (8) and so that the diaphragm (119) is approximately vertical. A cutting assembly, (130) moves into the abdominal cavity adjacent to the diaphragm (119), and a cutting means (28) cuts the diaphragm (119) around the periphery. A brisket shearing means (21) cuts the brisket (20) with a shearing action along the brisket (20) from the abdomen and towards the neck end of the brisket (20). The reaction member (188) is pivotally movable relative to the brisket (20) about a rear end to generally follow the contours of the brisket (20).Type: GrantFiled: July 2, 1991Date of Patent: August 18, 1992Assignees: Commonwealth Scientific & Industrial Research Organization, Austrialian Meat & Live-stock Research & Development CorporationInventors: Russel J. Rankin, David John De Chastel, deceased, Graeme L. Wescombe, David T. Kerr, Phillip R. Boyce, Raymond M. White, Robert W. Tritchler, John W. Buhot
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Patent number: 5136249Abstract: Probes for the measurement of moisture content, solids content, and electrical conductivity of porous or fibrous materials, slurries, liquids, and the like using Time Domain Reflectometry comprising a conductive wire or rod extending outwardly from the embedded at one end in, a conductive base and insulated from the base by a region of dielectric material. The wire and base being dimensioned and spaced to emulate a coaxial transmission line with the wire or rod being the center conductor of the transmission line and the conductive base forming the coaxial shield.Type: GrantFiled: December 12, 1990Date of Patent: August 4, 1992Assignee: Commonwealth Scientific & Industrial Research OrganizationInventors: Ian White, Steven J. Zegelin
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Patent number: 5118898Abstract: A process for the production of ethylene from a methane rich gas stream and an ethane rich gas stream. The process comprises the steps of:(a) introducing the methane rich gas stream together with molecular oxygen into a lower zone of a fluidized-bed of particles which are catalytically active in promoting an exothermic oxidative coupling reaction to produce ethylene and other hydrocarbons,(b) mixing the ethane rich gas stream into the fluidized-bed above the level at which substantially all of the molecular oxygen has been consumed, and(c) subjecting the mixture resulting from step (b) to an endothermic pyrolysis reaction in an upper zone of the fluidized-bed to produce further ethylene and other olefinically unsaturated hydrocarbons.The process is characterized in that the pyrolysis step (c) is carried out substantially without the addition of heat to the reactor, other than the heat content of the methane rich and ethane rich gas streams and the heat generated by the exothermic oxidative coupling reaction.Type: GrantFiled: March 14, 1990Date of Patent: June 2, 1992Assignees: The Broken Hill Proprietary Company Limited, Commonwealth Scientific & Industrial Research OrganizationInventors: Ralph J. Tyler, James H. Edwards, Peter J. Jackson
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Patent number: 5098472Abstract: There is disclosed a preservative composition which is ultra stable in the presence of wood extractives comprising (a) an emulsion of a wood preserative grade creosote; (b) 5-95% water; (c) one or more pre-dispersed micronized pigments; (d) a rheology structuring agent present in an amount of 2.5 weight percent or less; (e) 0.25 to 10 weight percent of a soap which is an alkali metal salt of a wood derived resin acid; (f) 0.1 to 5 weight percent of a surfactant; (g) 0.25 to 2 weight percent of a natural or synthetic pigment modifying resins or anti-settle additive; and (h) 0.25 to 5 weight percent of a lignin sulfonate. The emulsion is produced under conditions of ultra-high sheer. A process for the manufacture of the preservative composition is also disclosed.Type: GrantFiled: September 13, 1990Date of Patent: March 24, 1992Assignees: Commonwealth Scientific & Industrial Research Organization, Koppers Australia Pty. LimitedInventors: John B. Watkins, Harry Greaves, Chen W. Chin
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Patent number: 5001060Abstract: DNA sequence elements which effect anaerobic induction of genes in plants are identified and characterized. These sequence elements, designated anaerobic regulatory elements, confer inducibility by anaerobic conditions on downstress plant-expressible promoters and their associated structural genes. In particular, those sequences associated with anaerobic induction of the maize alcohol dehydrogenase and aldolase genes have been identified. These sequence elements can be employed in combination with appropriately positioned plant-expressible genes to produce chimeric, anaerobically inducible genes. Such constructs are useful for the selective expression of structural genes under anaerobic conditions in plants.Type: GrantFiled: June 15, 1987Date of Patent: March 19, 1991Assignees: Lubrizol Enterprises, Inc., Commonwealth Scientific & Industrial Research OrganizationInventors: James. W. Peacock, John C. Walker, Elizabeth Dennis, Elizabeth A. Howard
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Patent number: 4987104Abstract: A method of forming a dense ceramic product comprised of silicon nitride and silicon oxynitride or aluminum substituted derivative of either in which silica is subjected to a controlled partial carbothermal reduction process in the presence of nitrogen to produce residual silica and silicon nitride, fabricating the resulting material into the desired shape and heating in a nitrogen atmopshere at a temperature of from 1400.degree. C. to 2000.degree. C. with or without pressure to form the product. The silica may conveniently be derived from pyrolysed rice hulls. The product may also comprise silicon carbide, which may be derived from the carbothermal reduction, and a glassy phase.Type: GrantFiled: November 1, 1988Date of Patent: January 22, 1991Assignee: Commonwealth Scientific & Industrial Research OrganizationInventor: Mark B. Trigg
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Patent number: 4953612Abstract: A composite article having a first and a second metal component, and a resultant composite metal article, wherein a flux coating is applied over at least a substantially oxide-free bond surface of the first component, the first component with the flux coating is preheated and, with the first component positioned in a mold to fill a portion of a cavity of the mold, a melt for providing the second component is poured into the mold so as to flow over the bond surface; the first component being preheated to a first temperature and the melt being poured at a second temperature such that, on flowing over the bond surface, the melt displaces the flux coating and wets the bond surface, and that such initial temperature equilibration between the surface and the melt results in an interface temperature therebetween at least equal to the liquidus temperature of the melt, thereby resulting on solidification of the melt in attainment of a bond between the components.Type: GrantFiled: June 2, 1989Date of Patent: September 4, 1990Assignees: Commonwealth Scientific & Industrial Research Organization, Vida-Weld Pty. LimitedInventors: Ian R. Sare, Ian Henderson, Teunis Heijkoop, Michael R. Bosworth, Ronald E. Aspin, Brian K. Arnold
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Patent number: 4882064Abstract: A method for removing suspended impurities and colored substances from water which is hard and/or has a pH in excess of 5 which comprises contacting the water at its natural pH with a coagulant/adsorbent which comprises a finely divided particulate mineral material, the individual particles of which have a thin hydroxylated surface layer having a positive zeta potential at the adsorption pH, and separating the thus treated water from the coagulant/adsorbent.Type: GrantFiled: June 19, 1987Date of Patent: November 21, 1989Assignee: Commonwealth Scientific and Research OrganizationInventors: David R. Dixon, Nevil J. Anderson
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Patent number: 4720993Abstract: A Sensor for measuring oxygen partial pressures in hot gases includes a semiconducting nonstoichiometric oxide material in the form of a solid solution in uranium dioxide UO.sub.2 of at least one other metal oxide having an oxygen/metal (O/M) ratio of less than two and a uranium/other metal (U/M) ratio such that the material has n-type conductivity. The sensor further includes at least one pair of electrodes contacting the nonstoichiometric oxide material at spaced apart locations for connection to a device for determining the resistance of the material between the electrodes.Type: GrantFiled: June 16, 1986Date of Patent: January 26, 1988Assignee: Commonwealth Scientific & Industrial Research OrganizationInventor: Sukhyinder P. S. Badwal