Patents Assigned to Como Holdings APS
  • Method for detecting IGFBP-4 protease without detecting IGFBP-4 protease/proMBP Complex
    Patent number: 7115382
    Abstract: Methods for screening for altered focal proliferation states in non-pregnant patients, which include detecting levels of pregnancy-associated plasma protein-A (PAPP-A) are described. Methods for identifying agents that alter the protease activity of PAPP-A, and pharmaceutical compositions and medical devices that include such agents are also described.
    Type: Grant
    Filed: March 15, 2000
    Date of Patent: October 3, 2006
    Assignees: Mayo Foundation for Medical Education and Research, Como Holdings APS
    Inventors: Michael Toft Overgaard, Claus Oxvig, Cheryl A. Conover