Abstract: A method for treatment or prevention of prostate cancer by administering an effective amount of a compound of the formula (I) or a pharmaceutically acceptable salt or ester thereof. In formula (I) (which follows), each of R.sup.1 and R.sup.2 is a hydrogen atom, a hydroxyl group, a protected hydroxyl group or a lower alkoxy group.

Abstract: 4-Methylpridazin-3-one compounds of the formula: ##STR1## [wherein, X represents a hydrogen or fluorine atom, and Y represents a hydrogen atom, C.sub.1 -C.sub.6 alkoxy, C.sub.3 -C.sub.6 alkoxy or C.sub.3 -C.sub.6 alkyloxy group] are produced by reacting 4-cyanopyridazin-3-one compounds of the formula: ##STR2## with a methylating agent. Therefore, the above 4-cyanopyridazin-3-one compounds are useful for producing the above herbicidal 4-methylpyridazin-3-one compounds as intermediates.

Abstract: The invention relates to a method for producing a bis(trifluoromethyl)benzene. This method includes the steps of (a) chlorinating a compound represented by the general formula (1) by chlorine, thereby to produce a trichloromethyltrifluoromethylbenzene; and (b) fluorinating the tricbloromethyltrifluoromethylbenzene by hydrogen fluoride, thereby to produce the bis(trifluoromethyl)benzene, ##STR1## where m is 1, 2 or 3. It is not necessary in the invention to handle solid in any reaction step.

Abstract: A vehicle for lithographic printing ink is prepared by using an improved binder resin of petroleum resin-modified phenol resin, in which the melt viscosity of the binder resin is maintained below a certain level to improve the workability in polymerization process and the misting in printing press is reduced by using the improved binder resin. In the preparation of the binder resin, acid modified hydrocarbon resin (A) is prepared by reacting components (a) mainly comprising five-membered cyclic compounds or their Diels-Alder reaction products with the components (b) comprising unsaturated carboxylic acids or their anhydrides, and said acid modified hydrocarbon resin (A) is then reacted with phenol resin (B) in which portions of the phenol resin are fed one after another, thereby producing said binder resin having the properties of: high weight average molecular weight, low melt viscosity and low ratio of melt viscosity to solution viscosity.

Abstract: A drawing board having a body and a generally transparent screen on the body. The screen has front and rear sides and contains a viscous opaque liquid and iron dust in the liquid. A magnetic eraser is movable within the body between a rest position away from the rear side of the screen and an operating position against that rear side for operation to move, through magnetic attraction, the iron dust away from the front side of the screen such that the iron dust becomes invisible on the screen. A spring biasses the eraser towards the rest position. A pen having a magnetic tip is used to draw on the screen.

Abstract: The invention relates to DNA constructs comprising an exogenous DNA sequence encoding a therapeutic protein product or itself a therapeutic product, DNA sequences derived from SV40 for replication and packaging of said construct into pseudovirions, and a DNA sequence encoding one or more regulatory elements sufficient for the expression of said therapeutic protein in a mammalian cell operatively linked thereto. The therapeutic product integrated into the DNA constructs of the invention can be a protein selected from the group consisting of enzymes, receptors, structural proteins, regulatory proteins and hormones. Of particular interest are .beta.-globin, P-glycoprotein and apolipoprotein A-I. Specific DNA constructs are plasmids pSO6.beta.-9, pSO6.beta.-1, pSO41, pSM1, and pSAIc. The invention also relates to SV40 pseudovirions containing a DNA construct according to the invention, which are capable of infecting and being expressed in mammalian cells.

Abstract: A 1-methylcarbapenem compound represented by the following formula (I): ##STR1## wherein R.sup.1 represents hydrogen or C.sub.1 -C.sub.4 alkyl; R.sup.2 represents hydrogen or an ester residue; and A represents a group of the formula (A1) ##STR2## wherein n is 0, 1 or 2, P is 0, 1 or 2, R.sup.3 is hydrogen or C.sub.1 -C.sub.4 alkyl and R.sup.4 is a group (Q2) ##STR3## wherein B is phenylene, phenylene(C.sub.1 -C.sub.3)alkyl, cyclohexylene, cyclohexylene(C.sub.1 -C.sub.3)alkyl or C.sub.1 -C.sub.5 alkylene, R.sup.7 is hydrogen or C.sub.1 -C.sub.4 alkyl, and R.sup.14 is a group --C(.dbd.NH)R.sup.8, wherein R.sup.8 is hydrogen or C.sub.1 -C.sub.4 alkyl or a group --NR.sup.9 R.sup.10, wherein R.sup.9 and R.sup.10 are the same or different and are hydrogen or C.sub.1 -C.sub.4 alkyl; or a pharmacologically acceptable salt thereof.

Abstract: A knitting machine including a first knitting station (51) for knitting a welt, a second knitting station (52) comprising a fully fashioned knitting head (54), and a transfer system including a welt transfer bar (60) and a transfer bar transport system (72, 73), the transfer bar being movable by the transport system from a loading station, whereat a welt knitted at the first knitting station (51) can be loaded onto the transfer bar (60), to an unloading station whereat the knitted welt loaded on the transfer bar can be transferred to the knitting head at the second knitting station (52).

Abstract: There is disclosed a method for producing an alkoxytitanium complex of formula (I), ##STR1## wherein Cp is a group having cyclopentadiene-type anion skeleton, A represents a carbon atom or silicon atom, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 each independently represent a hydrogen atom, an alkyl group having 1 to 10 carbon atoms which optionally may be substituted and the like, and R.sup.7 each independently represents an alkyl group having 1 to 10 carbon atoms which may be substituted and the like.

Abstract: A power supply apparatus for use with an arc utilizing device includes capacitors coupled in series between outputs of a rectifying unit, and inverters each of which is coupled across a respective one of the capacitors. Each inverter converts a DC voltage from the capacitor into a high frequency voltage and applies it to a respective one of transformers. A converter converts an output voltage from each transformer into a DC voltage for application to a load. An output detector generates a signal representative of an output current supplied to the load. A first voltage detector generates a signal representative of a first voltage to be applied to the inverters. A second voltage detector generates a signal representative of a second voltage across one of the capacitors.

Abstract: Novel pyridazin-3-one derivatives of formula [1] are provided, which are useful as active ingredients of herbicides, wherein R.sup.1 is haloalkyl; R.sup.2 and R.sup.3 are the same or different and are hydrogen, alkyl, haloalkyl, or alkoxyalkyl; and Q is [Q-1], [Q-2], [Q-3], [Q-4], or [Q-5]. Also provided are their use and intermediates for their production.

Abstract: There is disclosed a process for modifying fats and oils by an interesterification reaction to efficiently increase concentrations of the desired triglycerides. In the process, a step for subjecting a fat or oil to an interesterification reaction with a fatty acid or its lower alcohol ester in the presence of an enzyme catalyst and then a step for removing the fatty acid or its lower alcohol ester by distillation are repeated in multiple stages. The process is characterized by leaving the fat or oil and a feedstock fatty acid or its ester selectively in the distillation steps preceding the one in the final stage. According to this process, the amount of the fatty acid or its ester to be used can be reduced and the formation of by-products can be inhibited, thereby enabling to increase concentrations of the desired triglycerides more efficiently than conventional multistage interesterification processes.

Abstract: A pump frame (7) incorporates an upper opening (17), a lower opening (19) and a water passage (21) for connecting the two openings. To cause the lower opening (19) to be opened in water at a position adjacent a stern (1a) of a ship (1), the pump frame (7) is joined to a bottom (1b) of a ship (1). A pump casing (9) is secured to be stood erect above the pump frame (7). The pump casing (9) includes an impeller main shaft (33) stood erect. The impeller main shaft (33) is provided with an impeller (11) for sucking water from below the bottom (1b) through the lower opening (19) so as to pressurize the water. Water pressurized by the impeller (11) is jetted to a position behind the stern (1a) through a discharge pipe (13). As a result, the ship (1) is propelled. The foregoing water jet propulsion apparatus (5) enables sucking performance free from cavitation and excellent propelling performance to be obtained.

Abstract: Provided is a top board for a table, shelves or the like comprising a plurality of board sections to be connected laterally with one another by use of at least one connector, the board section having an engaging part on the laterial sides, into which the connector is inserted to connect the plural board sections.The disclosure also provides a connector which is mounted to an end of the board section to connect a plurality of board sections in users discretion.

Abstract: An isolated esterase gene coding for an esterase capable of causing asymmetric hydrolysis of an organic carboxylic acid ester of a cyclopentenolone of formula I: ##STR1## wherein R.sub.1 is hydrogen or methyl, and R.sub.2 is C.sub.1 -C.sub.10 alkyl, C.sub.2 -C.sub.10 alkenyl, C.sub.2 -C.sub.10 alkynyl, C.sub.1 -C.sub.4 haloalkyl, a C.sub.5 -C.sub.9 aliphatic hydrocarbon moiety which may be optionally protected on the terminal hydroxyl group thereof, or a C.sub.5 -C.sub.9 fatty acid residue which may be optionally protected on the terminal carboxyl group thereof, to produce the cyclopentenolone of formula I in (R)-form, and hybridizing to the base sequence of SEQ ID NO:1, is useful for the industrially favorable production of optically active cyclopentenolones of formula I which serve as the intermediates of drugs, agricultural chemicals or other active products.

Abstract: A cyclic amine derivative represented by the following formula: ##STR1## wherein R.sup.1 represents a substituted or unsubstituted phenyl group, R.sup.2 represents a substituted of unsubstituted C.sub.1 -C.sub.8 aliphatic acyl group, a substituted or unsubstituted benzoyl group or a C.sub.1 -C.sub.4 alkoxycarbonyl group, and R.sup.3 represents a substituted 3 to 7 membered saturated cyclic amino group which may form a fused ring; or pharmaceutically acceptable salts thereof. The compounds and salts have excellent platelet aggregation inhibitory action. They are useful for the treatment and prevention of such diseases as embolism, thrombosis or arteriosclerosis and for the preparation of pharmaceutical compositions for such uses.

Abstract: An accident sound detection circuit includes an accident sound detection block that detects an accident sound from a sound signal inputted from an environmental sound detection unit and outputs an accident sound detection signal a power spectrum calculator for obtaining a power spectrum in regard to a sound signal when acquiring the accident sound detection signal outputted from the accident sound detection block as a trigger signal, a spectrum pattern calculator for forming a pattern of the power spectrum, and a pattern comparator circuit for comparing the formed spectrum pattern and a set pattern set in a pattern generating circuit beforehand and generating a final accident sound detection signal if the patterns coincide with each other.