Patents Assigned to COMPASS PATHFINDER LIMITED
  • PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE
    Publication number: 20260159537
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Application
    Filed: August 11, 2025
    Publication date: June 11, 2026
    Applicant: Compass Pathfinder Limited
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, David E. NICHOLS
  • Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
    Patent number: 12643917
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Grant
    Filed: June 12, 2025
    Date of Patent: June 2, 2026
    Assignee: Compass Pathfinder Limited
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, David E. Nichols
  • Methods for treating anxiety disorders, headache disorders, and eating disorders with psilocybin
    Patent number: 12611418
    Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.
    Type: Grant
    Filed: August 11, 2025
    Date of Patent: April 28, 2026
    Assignee: Compass Pathfinder Limited
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, David E. Nichols, Hans Åke Eriksson, George Goldsmith, Ekaterina Malievskaia, Manon Cecile Elisabeth Veraart, Lars Christian Wilde
  • Processes for the production of tryptamines
    Patent number: 12595497
    Abstract: Disclosed herein are prokaryotic and eukaryotic microbes, including E. coli and S. cerevisiae, genetically altered to biosynthesize tryptamine and tryptamine derivatives. The microbes of the disclosure may be engineered to contain plasmids and stable gene integrations containing sufficient genetic information for conversion of an anthranilate or an indole to a tryptamine. The fermentative production of substituted tryptamines in a whole-cell biocatalyst may be useful for cost effective production of these compounds for therapeutic use.
    Type: Grant
    Filed: April 17, 2023
    Date of Patent: April 7, 2026
    Assignee: Compass Pathfinder Limited
    Inventor: Ryan Protzko
  • PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE
    Publication number: 20250368665
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Application
    Filed: August 11, 2025
    Publication date: December 4, 2025
    Applicant: Compass Pathfinder Limited
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS
  • METHODS FOR TREATING ANXIETY DISORDERS, HEADACHE DISORDERS, AND EATING DISORDERS WITH PSILOCYBIN
    Publication number: 20250367223
    Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.
    Type: Application
    Filed: August 11, 2025
    Publication date: December 4, 2025
    Applicant: Compass Pathfinder Limited
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS, Hans Åke ERIKSSON, George GOLDSMITH, Ekaterina MALIEVSKAIA, Manon Cecile Elisabeth VERAART, Lars Christian WILDE
  • PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE
    Publication number: 20250361251
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Application
    Filed: August 11, 2025
    Publication date: November 27, 2025
    Applicant: Compass Pathfinder Limited
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS
  • Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
    Patent number: 12459965
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Grant
    Filed: December 20, 2024
    Date of Patent: November 4, 2025
    Assignee: Compass Pathfinder Limited
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, Hemant Kashinath Patil, David E. Nichols
  • Method for treating anxiety disorders, headache disorders, and eating disorders with psilocybin
    Patent number: 12447164
    Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.
    Type: Grant
    Filed: November 29, 2023
    Date of Patent: October 21, 2025
    Assignee: Compass Pathfinder Limited
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, Hemant Kashinath Patil, David E. Nichols, Hans Åke Eriksson, George Goldsmith, Ekaterina Malievskaia, Manon Cecile Elisabeth Veraart, Lars Christian Wilde
  • Methods for treating anxiety disorders, headache disorders, and eating disorders with psilocybin
    Patent number: 12433904
    Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.
    Type: Grant
    Filed: April 17, 2020
    Date of Patent: October 7, 2025
    Assignee: Compass Pathfinder Limited
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, Hemant Kashinath Patil, David E. Nichols, Hans Ake Eriksson, George Goldsmith, Ekaterina Malievskaia, Manon Cecile Elisabeth Veraart, Lars Christian Wilde
  • METHODS OF TREATING NEUROCOGNITIVE DISORDERS, CHRONIC PAIN AND REDUCING INFLAMMATION
    Publication number: 20250302851
    Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat neurocognitive disorders (e.g., Alzheimer's disease, Parkinson's disease), ADHD, Epilepsy, Autism, Sleep-wake disorders, Chronic pain, Inflammatory Disorders, IBD, Stroke, ALS, and/or Multiple Sclerosis.
    Type: Application
    Filed: June 11, 2025
    Publication date: October 2, 2025
    Applicant: Compass Pathfinder Limited
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS, Hans Åke ERIKSSON, George GOLDSMITH, Ekaterina MALIEVSKAIA, Manon Cecile Elisabeth VERAART, Tobias Patrick WHELAN, Lars Christian WILDE
  • PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE
    Publication number: 20250304607
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Application
    Filed: June 12, 2025
    Publication date: October 2, 2025
    Applicant: Compass Pathfinder Limited
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS
  • Methods of treating neurocognitive disorders, chronic pain and reducing inflammation
    Patent number: 12377112
    Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat neurocognitive disorders (e.g., Alzheimer's disease, Parkinson's disease), ADHD, Epilepsy, Autism, Sleep-wake disorders, Chronic pain, Inflammatory Disorders, IBD, Stroke, ALS, and/or Multiple Sclerosis.
    Type: Grant
    Filed: April 17, 2020
    Date of Patent: August 5, 2025
    Assignee: Compass Pathfinder Limited
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, Hemant Kashinath Patil, David E. Nichols, Hans Ake Eriksson, George Goldsmith, Ekaterina Malievskaia, Manon Cecile Elisabeth Veraart, Tobias Patrick Whelan, Lars Christian Wilde
  • Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
    Patent number: 12312375
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Grant
    Filed: July 9, 2024
    Date of Patent: May 27, 2025
    Assignee: Compass Pathfinder Limited
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, Hemant Kashinath Patil, David E. Nichols
  • PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE
    Publication number: 20250122232
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Application
    Filed: December 20, 2024
    Publication date: April 17, 2025
    Applicant: Compass Pathfinder Limited
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS
  • TREATMENT OF TREATMENT RESISTANT DEPRESSION WITH PSILOCYBIN
    Publication number: 20250000881
    Abstract: The disclosure provides methods for treating treatment-resistant depression a subject in need thereof comprising administering to the subject two or more doses of psilocybin.
    Type: Application
    Filed: November 2, 2022
    Publication date: January 2, 2025
    Applicant: COMPASS PATHFINDER LIMITED
    Inventors: Trevor Anthony MILL, Guy Manning GOODWIN, Joyce TSAI, Lindsey MARWOOD, Sunil MISTRY
  • PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE
    Publication number: 20240360162
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Application
    Filed: July 9, 2024
    Publication date: October 31, 2024
    Applicant: Compass Pathfinder Limited
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS
  • METHOD FOR TREATING ANXIETY DISORDERS, HEADACHE DISORDERS, AND EATING DISORDERS WITH PSILOCYBIN
    Publication number: 20240252521
    Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.
    Type: Application
    Filed: November 29, 2023
    Publication date: August 1, 2024
    Applicant: Compass Pathfinder Limited
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS, Megan CROAL, Hans Åke ERIKSSON, George GOLDSMITH, Molly Tabitha HICKEY, Shaun HURLEY, Ekaterina MALIEVSKAIA, Lindsey MARWOOD, Drummond E-Wen Joe MCCULLOCH, Laurie Emma MEDHURST, Nathan POULSEN, Aslihan SELIMBEYOGLU, Anaïs SOULA, Amanda Tan SHUXIANG, Manon Cecile Elisabeth VERAART, Tobias Patrick WHELAN, Lars Christian WILDE, Stephen WRIGHT
  • PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE
    Publication number: 20240199660
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Application
    Filed: February 5, 2024
    Publication date: June 20, 2024
    Applicant: Compass Pathfinder Limited
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS
  • PSILOCYBIN COMPOSITIONS, METHODS OF MAKING AND METHODS OF USING THE SAME
    Publication number: 20240197758
    Abstract: The present disclosure provides pharmaceutical compositions comprising a therapeutically effective amount of psilocybin and one or more pharmaceutically acceptable excipients. Methods of making such compositions and use thereof in treating depressive disorders are also disclosed.
    Type: Application
    Filed: March 30, 2022
    Publication date: June 20, 2024
    Applicant: Compass Pathfinder Limited
    Inventors: David Philip ELDER, Nigel RICHARDSON