Patents Assigned to CompleGen Partners, Inc.
  • Compounds and methods for PKC theta inhibition
    Patent number: 8436025
    Abstract: The present invention provides a method of selectively inhibiting PKC? in the presence of PKC?, by administering to a subject in need thereof, a therapeutically effective amount of a compound of Formula I. The present invention also provides a method of inhibiting cytokine synthesis in a T cell, a method of inhibiting T cell proliferation, and a method of inhibiting the replication of and cytokine production by T lymphocytes, while not stimulating or inhibiting the replication of B lymphocytes.
    Type: Grant
    Filed: September 17, 2009
    Date of Patent: May 7, 2013
    Assignee: CompleGen Partners, Inc.
    Inventors: Janet Ajioka, Heidi S. Hummel, Rich B. Meyer, John Swindle