Abstract: Polypeptide and nucleic acid agents for treating diseases and conditions associated with complement are disclosed. Also disclosed are expression vectors, compositions and cells comprising the agents, and methods using the agents, e.g. for treatment.
Type:
Application
Filed:
January 5, 2024
Publication date:
July 30, 2026
Applicant:
Complement Therapeutics Limited
Inventors:
Simon J. Clark, Mustafa Munye, Sonika Rathi
Abstract: Polypeptides comprising a C3b binding region are disclosed, as well as nucleic acids and vectors encoding such polypeptides, and cells and compositions comprising such polypeptides. Also disclosed arc uses and methods using the polypeptides for treating and preventing diseases and conditions.
Type:
Grant
Filed:
October 20, 2022
Date of Patent:
February 10, 2026
Assignee:
Complement Therapeutics Limited
Inventors:
Paul Bishop, Simon Clark, Richard Unwin
Abstract: Polypeptides comprising a C3b binding region are disclosed, as well as nucleic acids and vectors encoding such polypeptides, and cells and compositions comprising such polypeptides. Also disclosed are uses and methods using the polypeptides for treating and preventing diseases and conditions.
Type:
Grant
Filed:
November 4, 2022
Date of Patent:
August 12, 2025
Assignee:
Complement Therapeutics Limited
Inventors:
Paul Bishop, Simon Clark, Richard Unwin
Abstract: Polypeptides comprising a C3b binding region are disclosed, as well as nucleic acids and vectors encoding such polypeptides, and cells and compositions comprising such polypeptides. Also disclosed are uses and methods using the polypeptides for treating and preventing diseases and conditions.
Type:
Grant
Filed:
January 15, 2019
Date of Patent:
December 13, 2022
Assignee:
Complement Therapeutics Limited
Inventors:
Paul Bishop, Simon Clark, Richard Unwin