Abstract: Compositions and methods are provided to increase the healthspan of a subject. Most typically, contemplated compositions are formulated for oral administration and comprise a synergistic combination of a first and a second polyamine (e.g., spermine and spermidine).
Abstract: A simplified synthetic process for production of spermine and spermidine are presented that can provide spermine and spermidine in free base or salt form. Advantageously, the synthetic procedure is safe, simple, and environmentally friendly, while at the same time also being cost-effective.
Abstract: Tributyrin and/or tributyrin derivatives are used to selectively increase the levels of Bifidobacteria in the gut. In preferred methods, the tributyrin and/or tributyrin derivatives are orally administered alone or in combination with a food item or other nutritionally acceptable carrier, and may further include Bifidobacteria. Tributyrin-enhanced Bifidobacterium strains are also contemplated that include Bifidobacteria previously cultured in tributyrin and/or tributyrin derivatives.
Abstract: Tributyrin and/or tributyrin derivatives are used to selectively increase the levels of Bifidobacteria in the gut. In preferred methods, the tributyrin and/or tributyrin derivatives are orally administered alone or in combination with a food item or other nutritionally acceptable carrier, and may further include Bifidobacteria. Tributyrin-enhanced Bifidobacterium strains are also contemplated that include Bifidobacteria previously cultured in tributyrin and/or tributyrin derivatives.
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