Patents Assigned to Comprehensive Biomarker Center GmbH
  • miRNA fingerprint in the diagnosis of lung cancer
    Patent number: 9758827
    Abstract: The present invention provides novel methods for diagnosing diseases based on the determination of specific miRNAs that have altered expression levels in disease states compared to healthy controls.
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: September 12, 2017
    Assignee: Comprehensive Biomarker Center GmbH
    Inventors: Andreas Keller, Eckart Meese, Anne Borries, Markus Beier
  • Complex sets of miRNAs as non-invasive biomarkers for colon cancer
    Patent number: 9631241
    Abstract: Described herein are non-invasive methods, kits and means for diagnosing and/or prognosing of colon cancer a body fluid sample from a subject. Further described herein are sets of polynucleotides or sets of primer pairs for detecting sets of miRNAs for diagnosing and/or prognosing of colon cancer in a body fluid sample from a subject. In addition, described herein are sets of miRNAs for diagnosing and/or prognosing of colon cancer in a body fluid sample from a subject.
    Type: Grant
    Filed: January 21, 2016
    Date of Patent: April 25, 2017
    Assignee: Comprehensive Biomarker Center GmbH
    Inventors: Andreas Keller, Markus Beier, Eckart Meese, Petra Leidinger, Anke Wendschlag
  • miRNA fingerprint in the diagnosis of COPD
    Patent number: 9528158
    Abstract: MicroRNAs (miRNA) are a recently discovered class of small non-coding RNAs (17-14 nucleotides). Due to their function as regulators of gene expression they play a critical role both in physiological and in pathological processes, such as cancer. The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls.
    Type: Grant
    Filed: June 30, 2015
    Date of Patent: December 27, 2016
    Assignee: Comprehensive Biomarker Center GmbH
    Inventors: Andreas Keller, Eckart Meese, Anne Borries, Markus Beier
  • COMPLEX SETS OF MIRNAS AS NON-INVASIVE BIOMARKERS FOR COLON CANCER
    Publication number: 20160138117
    Abstract: Described herein are non-invasive methods, kits and means for diagnosing and/or prognosing of colon cancer a body fluid sample from a subject. Further described herein are sets of polynucleotides or sets of primer pairs for detecting sets of miRNAs for diagnosing and/or prognosing of colon cancer in a body fluid sample from a subject. In addition, described herein are sets of miRNAs for diagnosing and/or prognosing of colon cancer in a body fluid sample from a subject.
    Type: Application
    Filed: January 21, 2016
    Publication date: May 19, 2016
    Applicant: Comprehensive Biomarker Center GmbH
    Inventors: Andreas Keller, Markus Beier, Eckart Meese, Petra Leidinger, Anke Wendschlag
  • Complex sets of miRNAs as non-invasive biomarkers for colon cancer
    Patent number: 9249469
    Abstract: The present invention relates to non-invasive methods, kits and means for diagnosing and/or prognosing of colon cancer in a body fluid sample from a subject. Further, the present invention relates to set of polynucleotides or sets of primer pairs for detecting sets of miRNAs for diagnosing and/or prognosing of colon cancer in a body fluid sample from a subject. In addition, the present invention relates to sets of miRNAs for diagnosing and/or prognosing of colon cancer in a body fluid sample from a subject.
    Type: Grant
    Filed: August 3, 2012
    Date of Patent: February 2, 2016
    Assignee: Comprehensive Biomarker Center GmbH
    Inventors: Andreas Keller, Markus Beier, Eckart Meese, Petra Leidinger, Anke Wendschlag
  • miRNA fingerprint in the diagnosis of diseases
    Patent number: 9194002
    Abstract: The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls.
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: November 24, 2015
    Assignee: Comprehensive Biomarker Center GmbH
    Inventors: Andreas Keller, Eckart Meese, Anne Borries, Peer Friedrich Staehler, Markus Beier
  • miRNA fingerprint in the diagnosis of multiple sclerosis
    Patent number: 9187785
    Abstract: The present invention provides novel methods for diagnosing diseases based on the determination of specific miRNAs that have altered expression levels in disease states compared to healthy controls.
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: November 17, 2015
    Assignee: Comprehensive Biomarker Center GmbH
    Inventors: Andreas Keller, Eckart Meese, Anne Borries, Peer Friedrich Staehler, Markus Beier
  • miRNA FINGERPRINT IN THE DIAGNOSIS OF WILMS' TUMOUR
    Publication number: 20150031777
    Abstract: MicroRNAs (miRNA) are a recently discovered class of small non-coding RNAs (17-14 nucleotides). Due to their function as regulators of gene expression they play a critical role both in physiological and in pathological processes, such as cancer. The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls.
    Type: Application
    Filed: June 23, 2014
    Publication date: January 29, 2015
    Applicant: Comprehensive Biomarker Center GmbH
    Inventors: Andreas KELLER, Eckart MEESE, Anne BORRIES, Markus BEIER
  • COMPLEX SETS OF MIRNAS AS NON-INVASIVE BIOMARKERS FOR KIDNEY CANCER
    Publication number: 20140193822
    Abstract: The present invention relates to non-invasive methods, kits and means for diagnosing and/or prognosing of kidney cancer in a body fluid sample from a subject. Further, the present invention relates to set of polynucleotides or sets of primer pairs for detecting sets of miRNAs for diagnosing and/or prognosing of kidney cancer in a body fluid sample from a subject. In addition, the present invention relates to sets of miRNAs for diagnosing and/or prognosing of kidney cancer in a body fluid sample from a subject.
    Type: Application
    Filed: August 3, 2012
    Publication date: July 10, 2014
    Applicant: Comprehensive Biomarker Center GmbH
    Inventors: Andreas Keller, Markus Beier, Eckart Meese, Petra Leidinger, Anke Wendschlag
  • COMPLEX SETS OF MIRNAS AS NON-INVASIVE BIOMARKERS FOR DILATED CARDIOMYOPATHY
    Publication number: 20140194312
    Abstract: The present invention relates to non-invasive methods, kits and means for diagnosing and/or prognosing of dilated cardiomyopathy in a body fluid sample from a subject. Further, the present invention relates to set of polynucleotides or sets of primer pairs for detecting sets of miRNAs for diagnosing and/or prognosing of dilated cardiomyopathy in a body fluid sample from a subject. In addition, the present invention relates to sets of miRNAs for diagnosing and/or prognosing of dilated cardiomyopathy in a body fluid sample from a subject.
    Type: Application
    Filed: June 8, 2012
    Publication date: July 10, 2014
    Applicant: Comprehensive Biomarker Center GmbH
    Inventors: Andreas Keller, Benjamin Meder, Hugo Katus, Britta Vogel, Markus Beier