Abstract: Messages are targeted to travelers based on travel itineraries. Targeting may also be based on real-time travel status information. The targeted messages communicate their purpose and priority to respective travelers within the context of the travel itineraries. A disclosed method includes accessing a travel itinerary database including a plurality of travel itineraries. Each travel itinerary is associated with a traveler and defines itinerary segments of a corresponding travel schedule. A message is associated with a set of targeting rules used to identify a subset of itineraries in the travel itinerary database. The targeting rules may be used with real-time travel status information to identify the subset of itineraries.