Patents Assigned to ConfometRX Inc.
  • GPCR comprising an IC2 insertion
    Patent number: 8889377
    Abstract: Certain embodiments provide a method for crystallizing a GPCR. The method may employ a fusion protein comprising, from N-terminus to C-terminus: a) a first portion of a family C G-protein coupled receptor (GPCR), wherein the first portion comprises the TM1, TM2 and TM3, regions of the GPCR; b) a stable, folded protein insertion; and c) a second portion of the GPCR, wherein the second portion comprises the TM4, TM5 TM6 and TM7 regions of the GPCR.
    Type: Grant
    Filed: May 16, 2013
    Date of Patent: November 18, 2014
    Assignee: ConfometRx, Inc.
    Inventor: Brian Kobilka
  • METHOD AND COMPOSITION FOR CRYSTALLIZING A GPCR
    Publication number: 20140162341
    Abstract: Certain embodiments provide a method for crystallizing a GPCR. The method may employ a fusion protein comprising, from N-terminus to C-terminus: a) a first portion of a family C G-protein coupled receptor (GPCR), wherein the first portion comprises the TM1, TM2 and TM3, regions of the GPCR; b) a stable, folded protein insertion; and c) a second portion of the GPCR, wherein the second portion comprises the TM4, TM5 TM6 and TM7 regions of the GPCR.
    Type: Application
    Filed: May 16, 2013
    Publication date: June 12, 2014
    Applicant: ConfometRx, Inc.
    Inventor: ConfometRx, Inc.
  • GPCR comprising an IC2 insertion
    Patent number: 8470561
    Abstract: Certain embodiments provide a method for crystallizing a GPCR. The method may employ a fusion protein comprising, from N-terminus to C-terminus: a) a first portion of a family C G-protein coupled receptor (GPCR), wherein the first portion comprises the TM1, TM2 and TM3, regions of the GPCR; b) a stable, folded protein insertion; and c) a second portion of the GPCR, wherein the second portion comprises the TM4, TM5 TM6 and TM7 regions of the GPCR.
    Type: Grant
    Filed: August 29, 2011
    Date of Patent: June 25, 2013
    Assignee: ConfometRX Inc.
    Inventor: Brian Kobilka