Patents Assigned to CONICET
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Patent number: 11998877Abstract: A method for preparing a super-hydrophobic membrane by cleaning a metal mesh by immersion in an organic solvent; subjecting the cleaned metal mesh to a surface modification treatment to increase its hydrophilicity; coating the treated metal mesh with a hydrophobic organic substance; and drying the metal coated mesh for obtaining the super-hydrophobic membrane. The super-hydrophobic membrane obtained thereby.Type: GrantFiled: February 12, 2019Date of Patent: June 4, 2024Assignees: YPF TECNOLOGIA S.A., CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET)Inventors: Norma Beatriz D'Accorso, Mariana Sosa, Ricardo Martin Negri, Graciela Rojas, María Elena Oneto, Gabriel Lombardo
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Patent number: 11951170Abstract: The present disclosure provides a compound comprising a modified tetracycline derivative, covalently coupled through a linker to a low-hydrophobicity bioactive molecule useful for treating neurodegenerative diseases, wherein the modified tetracycline derivative is optionally defined by the following formula:Type: GrantFiled: March 14, 2023Date of Patent: April 9, 2024Assignees: Skybio LLC, Consejo Nacional de Investigaciones Cientificas y Ténicas (Conicet), Universidad Nacional de Tucumán, Universidad de Buenos Aires, Sistema Provincial De Salud De TucumánInventors: Oscar José Varela, Rosana Nieves Chehín, Cesar Luis Ávila, Sergio Benjamin Socías, Diego Ploper, Esteban Vera Pingitore, Analía Silvina Chaves, Martin Luong, Verónica Elena Manzano, Rodrigo Hernán Tomas Grau, Maria Florencia González Lizárraga, Adriana Andrea Kolender, Agustín Osvaldo Pernicone
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Patent number: 11946690Abstract: A cryogenic device for storing biological material containers comprises: a sealed cryogenic Dewar vessel; (b) a matrix of receptacles disposed in an inner space of the cryogenic Dewar vessel and configured for receiving and storing biological material containers; (c) means for loading and retrieving the biological material containers. The loading/retrieving means comprises a telescopic cane manipulator configured for loading and retrieving the biological material containers within the matrix. The receptacles are carried by a carousel member rotatable around an axis thereof. The receptacles are arranged into a number of groups distributed over the carousel member. Each group of the receptacles has a central point positioned at distance R1 from the rotation axis of the carousel member. a center of each receptacle within the group is positioned around a central point thereof at distance R2.Type: GrantFiled: February 17, 2020Date of Patent: April 2, 2024Assignee: National Scientific and Technical Research Council—Argentina (CONICET)Inventors: Demian Gustavo Slobinsky, Juan Pablo Peralta
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Patent number: 11912931Abstract: A polymeric surfactant for use in chemical enhanced oil recovery, including a terpolymer of a first non-ionic monomer, a second non-ionic monomer, and an ionic monomer, the first non-ionic monomer being a hydrophilic monomer and the second non-ionic monomer being a hydrophobic monomer, the ionic monomer being in a lower proportion than the first and second non-ionic monomers. A method of preparation of polymeric surfactants.Type: GrantFiled: July 7, 2022Date of Patent: February 27, 2024Assignees: YPF TECNOLOGÍA S.A., CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET)Inventors: Omar Azzaroni, Juan Martín Giussi, Agustín Iborra, Isabel Vega
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Patent number: 11835665Abstract: A detector of thermal neutrons, fast neutrons and gamma photons that is based on a Cherenkov radiation detector in water and that allows large active volumes of detection at a relatively low cost and higher intensity signals, wherein said detector comprises a container comprising at least a lid; a photon reflective and diffusive coating inside the container; an aqueous solution contained in the container, which comprises sodium chloride (NaCl); and a light sensing device optically coupled to the aqueous solution.Type: GrantFiled: February 4, 2020Date of Patent: December 5, 2023Assignees: CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET), INIS BIOTECH LLC, COMISIÓN NACIONAL DE ENERGÍA ATÓMICA (CNEA)Inventors: Mariano Gómez Berisso, Juan J. Blostein, José Lipovetzky, Martín Pérez, Iván P. Sidelnik, Miguel F. Sofo Haro, Fabricio P. Alcalde Bessia, Luis H. Arnaldi, Hernán G. Asorey
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Patent number: 11787909Abstract: Acrylamide-derived hydrogels and methods of fabrication thereof from an acrylic monomer, a crosslinking agent comprising an organosilicon compound, a polymerization initiator, a solvent and a polymerization accelerator, as well as their use in controlling circulation losses. The obtained hydrogels interact with the walls of the reservoir and exhibits an increase in viscosity, either at delayed times or in response to a given stimulus, such as changes in temperature, pressure, pH, salinity, using a simple and easily scalable methodology.Type: GrantFiled: December 23, 2019Date of Patent: October 17, 2023Assignees: YPF TECNOLOGIA S.A., UNIVERSIDAD DE BUENOS AIRES, CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET).Inventors: Joana Elisa Tasque, Pablo Alejandro Raffo, Isabel Natalia Vega, Norma Beatriz D'Accorso, Darío Alberto Contrera
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Patent number: 11723972Abstract: The present invention is based, in part, on the discovery that galectin-1 (Gal1) plays a role in viral-associated PTLD, e.g., EBV-associated PTLD and hypoxia associated angiogenesis disorders. Accordingly, the invention relates to compositions, kits, and method for diagnosing, prognosing, monitoring, treating and modulating viral-associated PTLD, e.g., EBV-associated PTLD and hypoxia associated angiogenesis disorders.Type: GrantFiled: September 17, 2019Date of Patent: August 15, 2023Assignees: Dana-Farber Cancer Institute, Inc., The Brigham and Women's Hospital, Inc., Consejo Nacional De Investigaciones Científicas y Técnicas (CONICET), Fundacion SalesInventors: Margaret Shipp, Jing Ouyang, Kunihiko Takeyama, Jeffery L. Kutok, Scott J. Rodig, Gabriel Rabinovich, Diego Omar Croci Russo, Mariana Salatino
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Patent number: 11690376Abstract: A formulation and a composition that comprises it for promoting the pollination of pear crops (Pyrus) by biasing the foraging preferences of the honey bee (Apis mellifera). The formulation comprises the compounds limonene, linalool and ?-pinene. Additionally, a method for targeting the bees' pollination activity towards the pear crops by using the formulation comprising the compounds limonene, linalool and ?-pinene.Type: GrantFiled: July 25, 2018Date of Patent: July 4, 2023Assignees: CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET), UNIVERSIDAD DE BUENOS AIRESInventors: Walter M. Farina, Paula Carolina Díaz
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Patent number: 11668664Abstract: A method and device for detection of solid organic matter and fluids in a shale rock by means of low field Nuclear Magnetic Resonance (NMR) in a single measurement, by submitting a rock sample to a 2D NMR assay comprising applying a 2D pulse sequence with a saturation-recovery, or inversion-recovery, in an indirect dimension and an FID-CPMG in a direct dimension. The method can be used as an analytical technique for rock samples from unconventional hydrocarbon reservoirs.Type: GrantFiled: October 27, 2020Date of Patent: June 6, 2023Assignees: YPF TECNOLOGIA S.A., CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET), UNIVERSIDAD NACIONAL DE CORDOBAInventors: Rodolfo Hector Acosta, Emilia Victoria Silletta, Gustavo Alberto Monti, Yamila Garro Linck, Paula Cecilia Bedini, Gabriela Soledad Vila, Diana María Masiero, Esteban Alejo Domené, Manuel Isaac Velasco
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Patent number: 11627740Abstract: A glycoside compound of fatty acids that includes the general formula: GalNAc-GalNAc-Glc-O—R, where GalNAc is ?- or ?-D-N-acetylgalactosamine, Glc-O—R is a molecule of ?- or ?-D-glucose esterified to a monounsaturated fatty acid (R), where R is selected from 12:1(n) and where n is an integer between 2 and 11; 11:1(n) and where n is an integer between 2 and 10; 10:1(n), and where n is an integer between 2 and 9; 9:1(n), and where n is an integer between 2 and 8; 8:1(n), and where n is an integer between 2 and 8; 7:1(n) and where n is an integer between 2 and 7; and 6:1(n), and where n is an integer between 2 and 6. The compound has activity against plant pathogens, and induces the defense, and promotes the growth, of plants.Type: GrantFiled: September 5, 2018Date of Patent: April 18, 2023Assignees: Consejo Nacional de Investigaciones Cientificas y Técnicas (CONICET), ESTACION EXPERIMENTAL AGROINDUSTRIAL OBISPO COLOMBRESInventors: Atilio Pedro Castagnaro, Maria Paula Filippone, Bjorn Gunnar Viking Welin, Carlos Froilan Grellet Bournonville, Alicia Ines de Fatima Mamaní, Pía de los Angeles Di Peto
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Patent number: 11598704Abstract: A device and method for testing a rock specimen in order to determine the fracture toughness (KIC) thereof. The device comprises: a frame; a hydraulic pressure testing rig supported by the frame and comprising a pressure gauge, a lever and a pressure diaphragm; a storage tank for storing hydraulic fluid and supported by the frame; and a pressure chamber supported by the frame, in which the test specimen is placed to be subjected to hydrostatic pressure through conduits that connect said pressure chamber with the storage tank in fluid communication.Type: GrantFiled: November 5, 2020Date of Patent: March 7, 2023Assignees: YPF TECNOLOGÍA S.A., CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET)Inventors: Santiago Serebrinsky, Humberto Celleri, Walter Morris, Anibal Márquez, Juan Belmonte
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Publication number: 20230031265Abstract: Provided herein are devices, methods and compositions useful in obtaining aptamers for biosensor probes. Such methods, devices and compositions are useful for novel clinical or companion drug diagnostic and personalized theranostic assays.Type: ApplicationFiled: August 11, 2022Publication date: February 2, 2023Applicants: APLIFE BIOTECH CORPORATION, CONSEJO NACIONAL DE IN- VESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET)Inventors: Tomas Guido ROZENBLUM, Ivan Gustavo POLLITZER
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Patent number: 11533916Abstract: Disclosed is a bioinsecticide formulation comprising highly resistant Beauveria bassiana microsclerotia and to its use for insect control, in particular for control of insects in grain silos, and to a method of preparation of said formulation. The microsclerotia are obtained in a culture medium comprising an iron (II) compound at a concentration of approximately 0.2 g/L.Type: GrantFiled: March 6, 2020Date of Patent: December 27, 2022Assignees: YPF TECNOLOGÍA S.A., CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET), UNIVERSIDAD NACIONAL DE LA PLATA (UNLP)Inventors: Sebastián Alejandro Trejo, Sebastián Reinoso, Walter Alberto Vargas, Eliana Abrahamovich, Nicolás Pedrini, Juan Roberto Girotti, Marta Patricia Juárez
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Patent number: 11535858Abstract: The present invention generally relates to the field of genetic engineering and obtaining transgenic traits for agronomic applications. More specifically, the present invention relates to a specific transgenic event in agricultural crops that improves plant characteristics. Yet more specifically, the invention relates to a polynucleotide construct comprising a gene from Arabidopsis thaliana. In particular, the polynucleotide construct of the invention comprises the gene AtBBX21 which encodes a B-box protein from Arabidopsis thaliana. The transgenic event of the invention increases green and seed yield, reduces photoinhibition, improves water use efficiency, increases tuber and chlorophyll production and improves photosynthetic rates, among others. The polynucleotide construct of the invention comprises a sequence depicted as SEQ ID NO: 1. The invention also provides a transgenic plant transformed with said polynucleotide construct, wherein said plant exhibits improved characteristics.Type: GrantFiled: March 13, 2020Date of Patent: December 27, 2022Assignees: CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET), UNIVERSIDAD DE BUENOS AIRESInventors: Javier Francisco Botto, Carlos Daniel Crocco
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Publication number: 20220315671Abstract: Crystalline starch nano-microparticle product, gels and procedures are disclosed, wherein the nano-microparticle product comprises between 60% and 70% crystalline nano-microparticles and between 40% and 30% modified starch grains, wherein at least 90% of the nano-microparticles have sizes less than 200 nm and more than 40% of said nano-microparticles are less than 100 nm. The nano-microparticles can be mixed with boiling water, giving rise to gels that are useful in coating food, making creams and other uses, including the controlled release of different compounds.Type: ApplicationFiled: April 6, 2022Publication date: October 6, 2022Applicants: UNIVERSIDAD DE BUENOS AIRES, CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICASY TÉCNICAS CONICETInventors: Silvia Nair Goyanes, Gerardo Héctor Rubiolo, Norma Beatriz D'accorso, Lucía Mercedes Famá, Paula Fabiana Gonzalez Seligra
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Patent number: 11459575Abstract: The present invention relates to modified bacterial polypeptides having immunomodulatory and immunostimulatory activity. Most specifically, the present invention relates to modified bacterial polypeptides having an amino acid sequence selected from SEQ ID NO. 1, SEQ ID NO. 2, SEQ ID NO. 3, SEQ ID NO. 4 and SEQ ID NO. 5. The modified polypeptides are the adjuvant components of a pharmaceutical composition for eliciting an immune response against an specific antigen present in the pharmaceutical composition. In a preferred embodiment, the invention provides a pharmaceutical composition for a vaccine which comprises an adjuvant component which is any one of the modified polypeptides, one or more antigens, together with a pharmaceutically acceptable excipient.Type: GrantFiled: February 8, 2019Date of Patent: October 4, 2022Assignees: CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET, UNIVERSIDAD NACIONAL DE GENERAL SAN MARTINInventors: Mirta L. Coria, Karina A. Pasquevich, Juliana Cassataro
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Patent number: 11457650Abstract: A formulation and a composition that comprises it for promoting the pollination of almond tree crops (Prunus dulcis) by biasing the foraging preferences of the honey bee (Apis mellifera). The formulation comprises the compounds limonene, linalool and benzaldehyde. Additionally, a method for targeting the bees' pollinizing activity towards the almond tree crops by using the formulation comprising the compounds limonene, linalool and benzaldehyde.Type: GrantFiled: July 25, 2018Date of Patent: October 4, 2022Assignees: CONSEJO NACIONAL DE INVESTIGACIONES CIENIIFICAS Y TECNICAS (CONICET), UNIVERSIDAD DE BUENOS AIRESInventors: Walter M. Farina, Maria Cecilia Estravis Barcala, Florencia Palottini
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Patent number: 11448656Abstract: The present invention concerns a composition comprising at least three peptides derived from Mycobacterium tuberculosis antigen Rv2626c, its use in the diagnostic of latently infected Mycobacterium tuberculosis (LTBI) subjects, corresponding methods of use and kits.Type: GrantFiled: July 17, 2018Date of Patent: September 20, 2022Assignees: CNRS, CONICET, INSTITUT JEAN PAOLI & IRENE CALMETES, UNIVERSITE D' AIX-MARSEILLE, INSERMInventors: Juan Iovanna, Virginia Pasquinelli, Maria Madgalena Gherardi, Hector Eduardo Chuluyan, Ana Inès Rovetta, Delfina Pena, Véronica Edith Garcia
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Publication number: 20220054651Abstract: The invention relates to a pharmaceutical composition soluble in an aqueous solution, which is characterised in that it comprises sialoglycosphingolipids; polypeptides selected from the group comprising antibodies, fragments and variants of same; and at least one therapeutically active substance, forming a ternary micellar complex of sialoglycosphingolipid-therapeutically active substance-polypeptide in which the polypeptides are non-covalently associated with the micelles formed by the sialoglycosphingolipid and the therapeutically active substance.Type: ApplicationFiled: December 14, 2018Publication date: February 24, 2022Applicants: Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Centro de Excelencia en Productos y Procesos (CEPRECOR)Inventors: Dante Miguel BELTRAMO, Ariel Gustavo GARRO, Roxana Valeria ALASINO, Victoria LEONHARD
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Patent number: 11253847Abstract: The invention relates to a method for producing catalysts by the method of combustion in solution, to the catalysts produced by said method, and to the particular use thereof in the reverse water-gas shift reaction and in the partial oxidation of the methane into synthesis gas. Therefore, it is understood that the present invention pertains to the area of the green industry aimed at the reduction of CO2 on the planet.Type: GrantFiled: December 28, 2017Date of Patent: February 22, 2022Assignees: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC), CONSEJO NATIONAL DE INVESTIGACIONES CIENTICAS Y TECNICAS (CONICET)Inventors: María Consuelo Álvarez Galván, Martín Dapena Ospina, José Antonio Alonso Alonso, Loreto Troncoso Aguilera, Vanesa Cascos Jiménez, José Miguel Campos Martín, José Luis García Fierro, Horacio Falcón Richeni