Abstract: A new cell line which is morphologically very similar to the beta cell of the Islets of Langerhans is obtained by transformation of pancreatic bovine cells. The transformed cells contain the diploid number of chromosomes for the bovine species and produce insulin which may be extracted.

Abstract: A newly discovered particle in the urine and serum of non-A, non-B hepatitis patients has been associated with non-A, non-B hepatitis. The particle resembles a togavirus and is 50-60 nm in diameter with a discrete core of about 40 nm in diameter. The virus loses its infectivity for tissue culture upon heating at 25.degree. C. in aqueous suspension or by exposure to ether. The particle may be cultured in vitro or recovered from body fluids or tissues to make immunoassays and vaccines. The immunoassays may be employed to detect the particle antigens or antibodies thereto in test samples.

Abstract: The artificial endocrine pancreas device comprises a container in which are provided one, or more, hollow fibres; in the container and on the outside of the fibres are placed pancreatic islet cells; each fibre has a porosity allowing substances of molecular weight less than 100,000 Daltons to pass through so that blood passing in the hollow fibres can pass nutrients to the cells and pick up hormones, but no antigen or antibody with a molecular weight above 100,000 Daltons can pass through.

Abstract: An apparatus useful in the addition of reagents in small quantities to micro reaction systems is described. The apparatus enables liquids to be dispensed within a narrow desired area of a receiving tube or other receptacle from a needle while avoiding undesired contact with tube walls. Guide means control the position of the needle with respect to the tube. The apparatus is particularly useful in connection with a radioimmune assay system wherein radioactive labelled protein is delivered to a tube.

Abstract: Long chain alcohol esters of amino acids are used as adjuvants in vaccines to provide an improved antigenic capability when compared with conventional adjuvants.