Patents Assigned to Connetics Australia Pty. Ltd.
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Publication number: 20060292080Abstract: A pharmaceutical aerosol foam composition, comprising: an effective amount of a pharmaceutically active ingredient, wherein said pharmaceutically active ingredient is a vitamin or analogue thereof; an occlusive agent; an aqueous solvent; an organic cosolvent; wherein the pharmaceutically active ingredient is insoluble in both water and the occlusive agent; and the occlusive agent being present in an amount sufficient to form an occlusive layer on the skin, in use. In a second embodiment, an oil-in water emulsion having a vitamin, an occlusive agent; an aqueous solvent; and an organic cosolvent, wherein the occlusive agent is present in an amount sufficient to form an occlusive layer on the skin.Type: ApplicationFiled: May 26, 2006Publication date: December 28, 2006Applicant: Connetics Australia Pty LtdInventors: Alby Abram, Richard Buchta, Robert Houlden, Rose Ye
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Patent number: 7141237Abstract: The present invention provides various pharmaceutically active topical delivery compositions. In particular, compositions of the present invention are present in a pressurized container comprising a quick-breaking alcoholic foaming agent, such that when the composition is released, i.e., dispensed, from the pressurized container, a quick-breaking temperature sensitive foam is formed. In addition, the present invention provides various aspects related to such compositions, including methods for modulating a foam characteristic, methods for improving the shelf-life of a pharmaceutically active compound, methods for the percutaneous treatment of various diseases, infections, and illnesses, and methods for evaluating foam characteristics.Type: GrantFiled: January 23, 2004Date of Patent: November 28, 2006Assignee: Connetics Australia Pty Ltd.Inventors: Albert Zorko Abram, Barry Thomas Hunt
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Publication number: 20060233727Abstract: The present invention provides a foam composition comprising an active agent. In particular, the foam composition produces a water resistant, preferably very water resistant, film upon application.Type: ApplicationFiled: July 22, 2005Publication date: October 19, 2006Applicant: Connetics Australia Pty Ltd.Inventors: Joan Huggins, Robert Houlden
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Patent number: 7118734Abstract: This invention relates to compositions suited to use as hair shampoos, and particularly those developed with a view to the treatment of a hair borne infestation, or of a skin disease of the scalp in addition to the primary purpose of hair cleaning and conditioning. In a first aspect of the invention there is provided a substantially non-aqueous liquid shampoo composition comprising at least one detergent, at least one active agent incompatible with water, an organic bulking agent and shampoo excipients, said organic bulking agent being miscible with water and miscible with said at least one detergent and shampoo excipients. It has been surprisingly found that replacing an aqueous bulking agent such as water with an organic compound which is compatible with active agents insoluble in water but which itself is miscible with water and miscible with detergents can produce a cosmetically and aesthetically acceptable non-aqueous liquid shampoo, particularly one having acceptable foaming characteristics.Type: GrantFiled: May 1, 2000Date of Patent: October 10, 2006Assignee: Connetics Australia Pty Ltd.Inventors: Lilian Fuchshuber, Ron Harding
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Publication number: 20060171898Abstract: The present invention provides a foamable pharmaceutical composition comprising a corticosteroid active substance, a quick-break foaming agent, a propellant and a buffering agent. The quick-break foaming agent typically comprises an aliphatic alcohol, water, a fatty alcohol and surface active agent. The compositions of the invention can be used to treat various skin disease, and in particular scalp psoriasis.Type: ApplicationFiled: March 30, 2006Publication date: August 3, 2006Applicant: Connetics Australia Pty LtdInventors: Julie Jones, Anthony Baker, Neil Halls, Peter Watmough, Peter Marriott
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Patent number: 7078058Abstract: A foamable pharmaceutical composition comprising a corticosteroid, a quick-break foaming agent, a propellant and a buffering agent, sufficient to buffer the composition to within the range of pH 3.0 to 6.0 is disclosed. The quick-break foaming agent typically comprises an aliphatic alcohol, water, a fatty alcohol and a surface active agent. Due to the nature of the compositions of the invention, they are especially well-suited for use in the treatment of various skin diseases, and in particular, in the treatment of scalp psoriasis.Type: GrantFiled: September 27, 2002Date of Patent: July 18, 2006Assignee: Connetics Australia Pty LtdInventors: Julie Irene Jones, Anthony Richard Baker, Neil Graham Halls, Peter Watmough, Peter Marriott
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Publication number: 20060127321Abstract: The present invention provides various pharmaceutically active topical delivery compositions. In particular, compositions of the present invention are present in a pressurized container comprising a quick-breaking alcoholic foaming agent, such that when the composition is released, i.e., dispensed, from the pressurized container, a quick-breaking temperature sensitive foam is formed. In addition, the present invention provides various aspects related to such compositions, including methods for modulating a foam characteristic, methods for improving the shelf-life of a pharmaceutically active compound, methods for the percutaneous treatment of various diseases, infections, and illnesses, and methods for evaluating foam characteristics.Type: ApplicationFiled: February 7, 2006Publication date: June 15, 2006Applicant: Connetics Australia Pty Ltd.Inventors: Albert Abram, Barry Hunt
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Publication number: 20060104912Abstract: A pharmaceutical aerosol foam composition including an effective amount of a pharmaceutically active ingredient; an occlusive agent; an aqueous solvent; and an organic cosolvent, the pharmaceutically active ingredient being insoluble in both water and the occlusive agent; the occlusive agent being present in an amount sufficient to form an occlusive layer on the skin, in use.Type: ApplicationFiled: December 16, 2005Publication date: May 18, 2006Applicant: Connetics Australia Pty LtdInventor: Albert Abram
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Patent number: 7029659Abstract: A topical mousse composition including an occlusive agent; an aqueous solvent; and an organic cosolvent, wherein the occlusive agent is present in an amount sufficient to form an occlusive layer on the skin.Type: GrantFiled: January 27, 2004Date of Patent: April 18, 2006Assignee: Connetics Australia Pty Ltd.Inventor: Albert Zorko Abram
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Publication number: 20060067894Abstract: The present invention provides a foam composition comprising an active agent. In particular, the foam composition produces a water resistant, preferably very water resistant, film upon application.Type: ApplicationFiled: July 22, 2005Publication date: March 30, 2006Applicant: Connetics Australia Pty Ltd.Inventors: Joan Huggins, Robert Houlden
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Publication number: 20060057168Abstract: There is provided a process for the preparation of an oil in water (O/W) microemulsion or sub-micron emulsion composition for dermal delivery of at least one pharmaceutically active ingredient, the method including the steps of a) Admixing a first part including at least one of the group consisting of animal, mineral or vegetable oils, silanes, siloxanes, esters, fatty acids, fats, halogen compounds or alkoxylated alcohols; and one or more lipophilic surfactants, and a second part including water and at least one hydrophilic surfactant to achieve homogeneity, b) heating the mix of step a) to a phase assembly temperature in the range of 40-99° C., preferably 45-95° C., more preferably 65-85° C. with continuous mixing to obtain a microemulsion or sub-micron emulsion, c) allowing said microemulsion or sub-micron emulsion to cool, and d) adding a third part to said microemulsion or sub-micron emulsion at a temperature between 2° C.Type: ApplicationFiled: August 31, 2005Publication date: March 16, 2006Applicant: Connetics Australia Pty LtdInventors: Maria Larm, Ronald Harding
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Patent number: 6946120Abstract: A pharmaceutical composition for topical administration, including, as the pharmaceutically active component, at least 5% by weight, based on the total weight of the composition of a piperidinopyrimidine derivative or a pharmaceutically acceptable salt thereof; an acid in an amount to completely solubilise the piperidinopyrimidine derivative or a pharmaceutically acceptable salt thereof; a solvent composition including at least two of water, a lower alcohol and a co-solvent selected from one or more of the group consisting of aromatic and polyhydric alcohols; wherein when the co-solvent includes propylene glycol, it is present in an amount of less than approximately 10% by weight.Type: GrantFiled: April 16, 2002Date of Patent: September 20, 2005Assignee: Connetics Australia Pty. Ltd.Inventors: Tony Wai-Chiu So, Peter Paul Deo, Russell John Tait
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Publication number: 20050175641Abstract: The invention relates to a substantially homogeneous liquid composition capable of percutaneous delivery of one or more physiologically active agents, the composition including at least one physiologically active agent, a volatile solvent, and a rate modulating carrier comprising a hydrophilic polymer and a hydrophobic polymer the combination of the hydrophilic and hydrophobic polymers being elected to enable modulation of the rate of physiologically active agent. The invention also relates to method of delivering an effective amount of an active agent and method of treatment of a patient using the composition of the invention.Type: ApplicationFiled: September 10, 2004Publication date: August 11, 2005Applicant: Connetics Australia Pty LtdInventors: Peter Deo, Albert Abram
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Publication number: 20040184992Abstract: A pharmaceutical aerosol foam composition including an effective amount of a pharmaceutically active ingredient; an occlusive agent, an aqueous solvent; and an organic cosolvent, the pharmaceutically active ingredient being insoluble in both water and the occlusive agent; the occlusive agent being present in an amount sufficient to form an occlusive layer on the skin, in use.Type: ApplicationFiled: January 27, 2004Publication date: September 23, 2004Applicant: Connetics Australia Pty LtdInventor: Albert Zorko Abram
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Publication number: 20040151671Abstract: The present invention provides various pharmaceutically active topical delivery compositions. In particular, compositions of the present invention are present in a pressurized container comprising a quick-breaking alcoholic foaming agent, such that when the composition is released, i.e., dispensed, from the pressurized container, a quick-breaking temperature sensitive foam is formed. In addition, the present invention provides various aspects related to such compositions, including methods for modulating a foam characteristic, methods for improving the shelf-life of a pharmaceutically active compound, methods for the percutaneous treatment of various diseases, infections, and illnesses, and methods for evaluating foam characteristics.Type: ApplicationFiled: January 23, 2004Publication date: August 5, 2004Applicant: Connetics Australia Pty Ltd.Inventors: Albert Zorko Abram, Barry Thomas Hunt
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Patent number: 6730288Abstract: A pharmaceutical aerosol foam composition including an effective amount of a pharmaceutically active ingredient; an occlusive agent; an aqueous solvent; and an organic cosolvent, the pharmaceutically active ingredient being insoluble in both water and the occlusive agent; the occlusive agent being present in an amount sufficient to form an occlusive layer on the skin, in use.Type: GrantFiled: January 30, 2001Date of Patent: May 4, 2004Assignee: Connetics Australia Pty LtdInventor: Albert Zorko Abram