Patents Assigned to Consejos Superior de Investigaciones Cientificas
  • Device for determining the optical power of lenses and measurement method
    Patent number: 11300479
    Abstract: A device for measuring the optical power of an optical test system includes an optical-object-generating assembly, a support for the optical test system, a digital image detector, and a deflector assembly. The deflector assembly is intended to generate a lateral movement in respect of the initial optical image, thereby producing a shifted optical image and a reference optical image. The digital image detector captures the shifted optical image and the reference optical image in at least one digital image containing data relating to the lateral movement. The device also includes a processing component to calculate the optical power of the optical test system from the data relating to the lateral movement.
    Type: Grant
    Filed: June 28, 2018
    Date of Patent: April 12, 2022
    Assignees: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS, 2EYES VISION S.L.
    Inventors: Carlos Dorronsoro Díaz, Enrique Gambra Urralburu, Xoana Barcala Gosende, Victor Rodríguez López, Susana Marcos Celestino
  • Modified vaccine strain for the treatment of brucellosis
    Patent number: 11298416
    Abstract: The present application provides a modified Brucella strain, its use as a medicament, and its use as a medicament for the treatment and/or prevention of brucellosis. The Brucella strain has been modified through an inactivation of the wzm gene. Further, the present application provides a pharmaceutical composition which comprises the modified Brucella strain, its use as a medicament, and its use as a medicament for the treatment and/or prevention of brucellosis. The present application also provides a kit which comprises the modified Brucella strain and a pharmaceutically acceptable carrier or diluent and its use for the treatment and/or prevention of brucellosis.
    Type: Grant
    Filed: November 26, 2018
    Date of Patent: April 12, 2022
    Assignees: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC), UNIVERSIDAD PÚBLICA DE NAVARRA
    Inventors: María Jesús Grilló Dolset, Beatriz San Román Aberasturi, Leyre Palacios Chaves, Sara Mena Bueno, Ana Zabalza Baranguá
  • Photochemically induced engagement of intraocular implants
    Patent number: 11291537
    Abstract: An ocular implant and a method for implanting such an ocular implant inside an eye includes an optical portion and at least two polymer haptics for fixation of the ocular implant to tissue inside an eye. At least one portion of the haptics contains a photoinitiating agent delivery component. A kit for implanting an ocular implant in an eye includes an ocular implant at least two polymer haptics; and additionally a photoinitiating agent for at least partially impregnating a first portion of the ocular element or a second portion of tissue in the eye; and, a light source for providing light of a wavelength adapted to excite the photoinitiating agent.
    Type: Grant
    Filed: August 9, 2019
    Date of Patent: April 5, 2022
    Assignees: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS, THE GENERAL HOSPITAL CORPORATION
    Inventors: Susana Marcos Celestino, Carlos Dorronsoro Díaz, Nicolás Alejandre Alba, Andrés De La Hoz Durán, Irene Emily Kochevar
  • USES OF MESENCHYMAL STEM CELLS
    Publication number: 20220088084
    Abstract: The invention relates to the use of mesenchymal stem cells (MSCs) for treating systemic inflammatory response syndrome (SIRS) in a subject. The invention provides compositions, uses and methods for the treatment of SIRS.
    Type: Application
    Filed: October 8, 2021
    Publication date: March 24, 2022
    Applicants: Consejo Superior de Investigaciones Cientificas, TiGenix, S.A.U., Universidad de Sevilla
    Inventors: Mario DELGADO, Elena GONZALEZ-REY, Dirk BÜSCHER
  • Method for producing catalysts of formula my(Ce1-xLxO2-x/2)1-y for the use thereof in the reverse water-gas shift reaction and partial oxidation of methane into synthesis gas by means of the method of combustion in solution
    Patent number: 11253847
    Abstract: The invention relates to a method for producing catalysts by the method of combustion in solution, to the catalysts produced by said method, and to the particular use thereof in the reverse water-gas shift reaction and in the partial oxidation of the methane into synthesis gas. Therefore, it is understood that the present invention pertains to the area of the green industry aimed at the reduction of CO2 on the planet.
    Type: Grant
    Filed: December 28, 2017
    Date of Patent: February 22, 2022
    Assignees: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC), CONSEJO NATIONAL DE INVESTIGACIONES CIENTICAS Y TECNICAS (CONICET)
    Inventors: María Consuelo Álvarez Galván, Martín Dapena Ospina, José Antonio Alonso Alonso, Loreto Troncoso Aguilera, Vanesa Cascos Jiménez, José Miguel Campos Martín, José Luis García Fierro, Horacio Falcón Richeni
  • System and method for industrial encapsulation of thermolabile substances
    Patent number: 11253833
    Abstract: A facility for industrial drying and/or encapsulation of thermolabile substances comprising at least one injection unit (1) wherein the thermolabile substance is introduced, an encapsulating material when the facility is used to encapsulate, a solvent, additives and an injection gas flow for obtaining droplets from the thermolabile substance. It further comprises a drying unit (2) through which the droplets and a drying gas are introduced for evaporating the solvent and comprises a collection unit (3) configured to separate the microcapsules generated from the drying gas and which is selected from a cartridge filter collector, a cyclone collector or a combination of the two. It also describes a method for the industrial encapsulation of thermolabile substances which is carried out at the proposed facility.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: February 22, 2022
    Assignees: BIOINICIA, S.L., CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)
    Inventors: José María Lagaron Cabello, Sergio Castro Reina, José Manuel Valle, David Galan Nevado
  • METHOD FOR DETERMINING A GRASPING HAND MODEL
    Publication number: 20220009091
    Abstract: Method for determining a grasping hand model suitable for grasping an object by obtaining a first RGB image including at least one object; obtaining an object model estimating a pose and shape of said object from the first image of the object; selecting a grasp taxonomy from a set of grasp taxonomies by means of a Convolutional Neural Network, with a cross entropy loss, thus, obtaining a set of parameters defining a coarse grasping hand model; refining the coarse grasping hand model, by minimizing loss functions referring to the parameters of the hand model for obtaining an operable grasping hand model while minimizing the distance between the finger of the hand model and the surface of the object and preventing interpenetration; and obtaining a mesh of the hand represented by the enhanced set of parameters.
    Type: Application
    Filed: June 8, 2021
    Publication date: January 13, 2022
    Applicants: Naver France, Consejo Superior de Investigaciones Cientificas (CSIC), Universitatpolitècnica De Catalunya Plaça d'Eusebi Güell 6 Edifici Vertex, Planta 1
    Inventors: Francesc Moreno Noguer, Guillem Alenyà Ribas, Enric Corona Puyane, Albert Pumarola Peris, Grégory Rogez
  • Acylated compounds for the treatment of ocular pathologies
    Patent number: 11213536
    Abstract: The present invention relates to the therapeutic use of acylated piceid derivative compounds in ocular pathologies, in particular retinitis pigmentosa and in age-related macular degeneration.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: January 4, 2022
    Assignees: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS, FUNDACION PUBLICA ANDALUZA PROGRESO Y SALUD
    Inventors: Juan Carlos Morales Sánchez, Pablo Peñalver Puente, Francisco Javier Díaz Corrales, María Lourdes Valdés Sánchez, Ana Belén García Delgado, Adoración Montero Sánchez
  • Molecular adjuvant and vaccine
    Patent number: 11179462
    Abstract: The invention relates to the fields of vaccines and vaccine adjuvants, and generally relates to polynucleotide adjuvants, polynucleotide vaccines and vaccine compositions. More specifically, the invention relates to said polynucleotides and vaccine compositions for use in inducing or enhancing a prophylactic or therapeutic immune response in a mammalian subject. Furthermore, it relates to said polynucleotides and vaccine compositions for use in the prophylactic or therapeutic treatment of an infectious disease, such as in the prophylactic or therapeutic treatment of leishmaniasis.
    Type: Grant
    Filed: January 16, 2020
    Date of Patent: November 23, 2021
    Assignees: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS, CZ VETERINARIA S.A.
    Inventors: Pedro José Alcolea Alcolea, Ana María Alonso Ayala, Vicente Emilio Larraga Rodríguez De Vera
  • GRAPHENE TRANSISTOR SYSTEM FOR MEASURING ELECTROPHYSIOLOGICAL SIGNALS
    Publication number: 20210345930
    Abstract: A graphene transistor system for measuring electrophysiological signals uses flexible epicortical and intracortical arrays of graphene solution-gated field-effect transistors (gSGFETs) to record infraslow signals alongside signals in the typical local field potential bandwidth. The graphene transistor system includes a processing unit, and at least one graphene transistor (gSGFET) a tunable voltage source connected to the drain and source terminals of the transistor (gSGFET), and at least one filter configured to acquire and split the signal from the transistor into at least a low frequency band signal and high frequency band signal, which are amplifiable with a gain value.
    Type: Application
    Filed: May 6, 2021
    Publication date: November 11, 2021
    Applicants: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS, CONSORCIO CENTRO DE INVESTIGACIÓN BIOMEDICA EN RED, M.P., INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS (ICREA), FUNDACIÓ INSTITUT CATALÀ DE NANOCIÈNCIA I NANOTECNOLOGIA (ICN2), INSTITUTO DE INVESTIGACIONES BIOMÉDICAS AUGUST PI SUNYER (IDIBAPS)
    Inventors: Antón GUIMERÁ BRUNET, Eduard MASVIDAL CODINA, Rosa VILLA SANZ, José Antonio GARRIDO ARIZA, Xavier ILLA VILA, Maria Victoria SANCHEZ VIVES
  • Method and apparatus for recovering fibers embedded in a composite material
    Patent number: 11168261
    Abstract: A method for recovering fibers embedded in a composite material including loading a furnace chamber with a volume of the composite material; thermolyzing the composite material in the furnace chamber, resulting in a gaseous fraction that is continuously evacuated from the furnace chamber, and a residue of fibers covered with char that is left in the furnace chamber; cracking the gaseous fraction from the thermolyzing operation, resulting in a mixture of condensable and non-condensable gases that can be recycled; injecting a stream of an oxygen-containing gas into the still hot furnace chamber after the thermolyzing is completed therein, to burn the char from the fibers in an exothermic combustion.
    Type: Grant
    Filed: June 1, 2018
    Date of Patent: November 9, 2021
    Assignees: BCIRCULAR COMPOSITES, SOCIEDAD LIMITADA, CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC)
    Inventors: Roger Grau Garcia, Ferran Grau Garcia, Oriol Grau Garcia, Felix Antonio Lopez Gomez, Olga Rodriguez Largo
  • METHODS OF HEAVY REFORMATE CONVERSION INTO AROMATIC COMPOUNDS
    Publication number: 20210340080
    Abstract: Method of making BTX compounds including benzene, toluene, and xylene, including feeding heavy reformate to a reactor containing a composite zeolite catalyst. The composite zeolite catalyst includes a mixture of layered mordenite (MOR-L) comprising a layered or rod-type morphology with a layer thickness less than 30 nm and ZSM-5. The MOR-L, the ZSM-5, or both include one or more impregnated metals. The method further includes producing the BTX compounds by simultaneously performing transalkylation and dealkylation of the heavy reformate in the reactor. The composite zeolite catalyst is able to simultaneously catalyze both the transalkylation and dealkylation reactions.
    Type: Application
    Filed: July 13, 2021
    Publication date: November 4, 2021
    Applicants: Saudi Arabian Oil Company, Universitat Politecnica De Valencia, Consejo Superior De Investigaciones Cientificas
    Inventors: Raed Hasan Abudawoud, Avelino Corma Canos, M. Teresa Portilla Ovejero, Vicente J. Margarit Benavent, M. Teresa Navarro Villalba, M. Cristina Martinez Sanchez, Ibrahim M. Al-Zahrani
  • Monolithic quantum light source device and quantum optical circuit thereof
    Patent number: 11152535
    Abstract: This document describes a device that is monolithic and capable of emitting quantum light without using previous configurations known in the art that require certain elements which yield certain disadvantages, which may be solved by implementing the device of the invention described herein. In this way the use of a transmitter which controls the state of charge or the wavelength of quantum light emitters independently of current in the device is implemented and does function properly when quantum light emitters are embedded in photonic structures, like microcavities or photonic crystals (PC); this is achieved by stacking semiconductor layers with different composition and doping types. A quantum light emitter circuit, which is a quantum optical circuit comprising at least two of said devices, is also an as aspect of the invention disclosed herein.
    Type: Grant
    Filed: February 6, 2018
    Date of Patent: October 19, 2021
    Assignee: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)
    Inventors: Benito Alén Millán, David Fuster Signes, Yolanda González Díaz, Luisa González Sotos
  • CIRCUIT FOR THE MULTIPLEXING AND READ-OUT OF VARIABLE-RESISTANCE SENSOR ARRAYS
    Publication number: 20210321053
    Abstract: An apparatus and a method using no switching elements for multiplexing and reading arrays of sensors whose electrical resistance is modulated by the signals to be measured are proposed. Sensor elements are arranged in groups and columns where each column is fed with a continuous voltage waveform of different amplitude, frequency and phase characteristics which then produce current signals that are modulated by the variable resistance signals to be measured. Modulated currents are summed row-wise and collected at the read-out circuits, either by applying a constant voltage to each row of the array or by connecting a capacitor and converting these current summations into output voltage signals. The read-out circuits de-multiplex each individual sensor signal to be measured by lock-in demodulation according to the frequencies and phases employed for the stimulation of each column.
    Type: Application
    Filed: August 2, 2019
    Publication date: October 14, 2021
    Applicants: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC), UNIVERSITAT AUTÒNOMA DE BARCELONA, FUNDACIÓ INSTITUT CATALÀ DE NANOCIÈNCIA I NANOTECNOLOGIA (ICN2), INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS
    Inventors: Anton GUIMERÀ BRUNET, Lluis Antoni TERÉS TERÉS, Michele DEI, Jose Agustín CISNEROS FERNÁNDEZ, Francisco SERRA GRAELLS, José Antonio GARRIDO ARIZA
  • Integrated polarization splitter
    Patent number: 11131809
    Abstract: The invention relates to an integrated polarisation splitter based on a sub-wavelength multimode interference coupler (110), in other words, a multimode interference coupler (110) with an anisotropic multimode waveguide region formed by a plurality of sections of core material (210) and a plurality of sections of a cladding material (230) alternately arranged in a periodic way, with a period (?) smaller than the wavelength of a light propagated through said anisotropic region. The core material sections (210) are rotated an angle (?) greater than zero with respect to a perpendicular with an input waveguide (120) to increase the anisotropic character of the multimode waveguide region.
    Type: Grant
    Filed: January 24, 2019
    Date of Patent: September 28, 2021
    Assignees: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC), UNIVERSIDAD DE MÁLAGA
    Inventors: Aitor Villafranca Velasco, Alaine Herrero Bermello, Pedro Corredera, Robert Halir, Alejandro Ortega Moñux, J. Gonzalo Wangüemert Pérez, Inigo Molina Fernández
  • Methods of heavy reformate conversion into aromatic compounds
    Patent number: 11091413
    Abstract: Method of making BTX compounds including benzene, toluene, and xylene, including feeding heavy reformate to a reactor containing a composite zeolite catalyst. The composite zeolite catalyst includes a mixture of layered mordenite (MOR-L) comprising a layered or rod-type morphology with a layer thickness less than 30 nm and ZSM-5. The MOR-L, the ZSM-5, or both include one or more impregnated metals. The method further includes producing the BTX compounds by simultaneously performing transalkylation and dealkylation of the heavy reformate in the reactor. The composite zeolite catalyst is able to simultaneously catalyze both the transalkylation and dealkylation reactions.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: August 17, 2021
    Assignees: Saudi Arabian Oil Company, Universitat Politecnica De Valencia, Consejo Superior De Investigaciones Cientificas
    Inventors: Raed Hasan Abudawoud, Avelino Corma Canos, M. Teresa Portilla Ovejero, Vicente J. Margarit Benavent, M. Teresa Navarro Villalba, M. Cristina Martinez Sanchez, Ibrahim M. Al-Zahrani
  • A method for controlling timing of events in a microfluidic device and a timer microfluidic device
    Publication number: 20210220821
    Abstract: A method for controlling timing of events in a microfluidic device and a timer microfluidic device are disclosed. The method comprises adding a liquid on a first end of a microfluidic device at a first time t0, the liquid flowing by capillarity towards a second end; producing, by a battery (12) included in the microfluidic device, energy from a second time tstart until a third time tend to feed an auxiliary device (16) connected to the battery (12). The battery (12) is sized and composed to provide a given amount of energy during a delivery energy time interval toperation, comprised between a time ton in which a voltage output of the battery (12) is above a threshold and a time toff in which the voltage output is below the threshold, to control the duration of an event including a selective activation and deactivation of said auxiliary device (16).
    Type: Application
    Filed: May 13, 2019
    Publication date: July 22, 2021
    Applicants: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS, INSTITUCIO CATALANA DE RECERCA I ESTUDIS AVANÇATS (ICREA), FUELIUM, SL
    Inventors: Juan Pablo ESQUIVEL BOJORQUEZ, Maria de les Neus SABATE VIZCARRA, Sergi GASSO PONS
  • Fatty acid amides for the prevention and/or treatment of steatohepatitis
    Patent number: 11058650
    Abstract: The invention relates to the use of fatty acid amides with phenylalkylamines and of a pharmaceutical composition comprising at least one of these compounds in the prevention and/or treatment of fatty liver or a pathological condition or disease caused by fatty liver, either alcoholic or non-alcoholic, and, in particular, for the prevention and/or treatment of the alcoholic steatohepatitis or non-alcoholic steatohepatitis (NASH).
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: July 13, 2021
    Assignees: FUNDACIÓN PÚBLICA ANDALUZA PARA LA INVESTIGACIÓN DE MÁLAGA EN BIOMEDICINA Y SALUD (FIMABIS), CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC), FUNDACIÓ INSTITUT MAR DTNVESTIGACIONS MÈDIOUES
    Inventors: Fernando Rodríguez De Fonseca, Francisco Javier Pavón Morón, Juan Manuel Decara Del Olmo, Antonia Serrano Criado, Jesús Joglar Tamargo, Pedro Clapés Saborit, Rafael De La Torre Fornell, Magí Ferre Albaladejo, María Isabel Covas Planells, Montserrat Fito Colomer, Bruno Almeida Cotrim
  • Preparation of bioconjugates and antibodies for the immunodetection of anatoxin-a
    Patent number: 11054415
    Abstract: The present invention relates to bioconjugates and labeled derivatives of anatoxin-a, at different positions of the molecule, suitable for producing antibodies with high affinity and specificity for anatoxin-a. At the same time, the present invention also relates to the use of bioconjugates of anatoxin-a and labeled derivatives of anatoxin-a as assay antigens. Moreover, the present invention also relates to methods for analyzing, concentrating and extracting anatoxin-a using the antibodies obtained, sometimes together with assay antigens which are bioconjugates or labeled derivatives. This invention also provides a kit for analyzing anatoxin-a which comprises antibodies against this cyanotoxin sometimes together with assay antigens which are bioconjugates or labeled derivatives of anatoxin-a.
    Type: Grant
    Filed: September 21, 2016
    Date of Patent: July 6, 2021
    Assignees: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS, UNIVERSITAT DE VALÈNCIA
    Inventors: Antonio Abad Fuentes, Josep Vicent Mercader Badia, Antonio Abad Somovilla, Consuelo Agulló Blanes, Guillermo Quiñones Reyes
  • Method for determining the risk of developing alzheimer's disease
    Patent number: 11047867
    Abstract: The present invention relates to an in vitro method for determining the risk of developing Alzheimer's disease or a cognitive disorder similar to said disease, an in vitro method for designing a personalized therapy in a subject suffering from mild cognitive impairment and an in vitro method for selecting a patient susceptible to be treated with a therapy for the prevention and/or treatment of Alzheimer's or a cognitive disorder similar to said disease based on determining, in a sample from the subject, the level of phosphorylation in threonine residues in E2F4 protein or in a functionally equivalent variant. The invention also relates to the use of E2F4 or a functionally equivalent variant thereof, wherein the E2F4 or variant is phosphorylated in threonine as a marker of the risk of developing Alzheimer's disease or a cognitive disorder similar to Alzheimer's disease.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: June 29, 2021
    Assignees: Consejo Superior de Investigaciones Cientificas, TETRANEURON S.L.
    Inventors: José María Frade López, Noelia López Sánchez