Abstract: 2-Cyclopenten-1-one and its derivatives comprising the cyclopentenone nucleus as inhibitors of the NF-kB factor, with anti-inflammatory, anti-proliferative, immunosuppressive, cytoprotective and antiviral activity, the substituents being selected among the ones which do not affect the NF-kB inhibitory activity.
Type:
Application
Filed:
May 10, 2002
Publication date:
September 26, 2002
Applicant:
Consiglio Nazionale Della Richere
Inventors:
Maria Gabriella Santoro, Antonio Rossi, Giuliano Elia