Patents Assigned to Consiglio Nazionale Delle Ricerche - Dinamite Spa
  • Process for the selective preparation of isosorbide-2-mononitrate from isosorbide-2,5-dinitrate
    Patent number: 4777274
    Abstract: A process for the preparation of isosorbide-2-mononitrate (I) ##STR1## from isosorbide-2,5-dinitrate (II) ##STR2## The isosorbide-2,5-dinitrate (II) is treated, in a reaction medium consisting of an aqueous organic solvent, with salts of metals of low oxidation state.Isosorbide-2-mononitrate (I) is obtained with high selectivity.
    Type: Grant
    Filed: November 7, 1986
    Date of Patent: October 11, 1988
    Assignee: Consiglio Nazionale Delle Ricerche - Dinamite Spa
    Inventors: Ottorino De Lucchi, Fabiola Filipuzzi, Giorgio Modena, Ettore Camera