Patents Assigned to Consorzio per la Gestione del Centro di Biotecnologia Avanzata
  • Cryoprotective aqueous solutions useful for the preservation of in vitro cultured epithelial sheets
    Patent number: 5670308
    Abstract: A method for the preservation of in vitro expanded epithelial sheets by incubation of the sheets in a cryopreserving solution characterized by lack of volume increase at the liquid-solid phase transition. The cryopreserving solutions comprise: a) polyethyleneglycols having molecular weight between 3 and 5 KD; and b) at least one cross-linking agent selected from polyols, polyamines, mono- or oligosaccharides, and polyethyleneglycols having molecular weight lower than 1 KD.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: September 23, 1997
    Assignees: Development Biotechnological Processes SNC di Pelliccia Maria Teresa, Consorzio per la Gestione del Centro di Biotecnologia Avanzata
    Inventors: Giuseppe Geraci, Mario De Rosa, Mose Rossi, Ranieri Cancedda, Michele De Luca, Graziella Pellegrini