Abstract: The present invention relates to a novel grape extract, particularly from white grape seeds, and processes for making such, that is useful for, inter alia, modulating oxidative stress, inflammation, and impaired insulin sensitivity in an individual, particularly an individual suffering from Metabolic Syndrome. The processes of the present invention produce a highly concentrated polyphenol product by maximizing extraction of monomeric and oligomeric procyanidins and minimizing extraction of polymeric procyanidins. The grape extract of the present invention comprises between about 5-15% monomers, about 5-20% dimers, about 3-10% trimers, about 2-10% tetramers, and about 2-10% pentamers by weight with a high percentage of galloylation. The grape extract of the present invention can be formulated into dietary supplements or pharmaceutical compositions, including capsules, tablets, powders, solutions, gels, suspensions, creams, gels, and the like.
Abstract: The present invention relates to a novel grape extract, and processes for making such, that is useful for, inter alia, treating pre-hypertension, Metabolic Syndrome and/or the conditions that comprise Metabolic Syndrome. The processes of the present invention produce a highly concentrated polyphenol product by maximizing extraction of monomeric and oligomeric procyanidins and minimizing extraction of polymeric procyanidins. The grape extract of the present invention comprises between about 5-15% monomers, about 5-20% dimers, about 3-10% trimers, about 2-10% tetramers, and about 2-10% pentamers by weight. The grape extract of the present invention can be formulated into dietary supplements, including capsules, tablets, powders, solutions, gels, suspensions, creams, gels, and the like. These dietary supplements in, for instance, powder or solution form, may be added to nutraceuticals, foods and/or beverages to form functional nutraceutical, food, and/or beverage products.
Type:
Grant
Filed:
July 28, 2010
Date of Patent:
December 13, 2011
Assignee:
Constellation Brands, Inc.
Inventors:
Anil Jageshwar Shrikhande, Haibo Wang, Steve Anthony Kupina
Abstract: The present invention relates to a novel grape extract, and processes for making such, that is useful for, inter alia, treating pre-hypertension, Metabolic Syndrome and/or the conditions that comprise Metabolic Syndrome. The processes of the present invention produce a highly concentrated polyphenol product by maximizing extraction of monomeric and oligomeric procyanidins and minimizing extraction of polymeric procyanidins. The grape extract of the present invention comprises between about 5-15% monomers, about 5-20% dimers, about 3-10% trimers, about 2-10% tetramers, and about 2-10% pentamers by weight. The grape extract of the present invention can be formulated into dietary supplements, including capsules, tablets, powders, solutions, gels, suspensions, creams, gels, and the like. These dietary supplements in, for instance, powder or solution form, may be added to nutraceuticals, foods and/or beverages to form functional nutraceutical, food, and/or beverage products.
Type:
Grant
Filed:
September 27, 2006
Date of Patent:
August 3, 2010
Assignee:
Constellation Brands, Inc.
Inventors:
Anil Jageshwar Shrikhande, Haibo Wang, Steve Anthony Kupina
Abstract: A process for making a low-alcohol wine is provided. The process includes the steps of separating grape juice into a high-sugar fraction and a low-sugar fraction prior to fermentation, blending additional grape juice into the low-sugar fraction to form a mixture and then fermenting the mixture to form a low-alcohol wine. In the case of red wine, a low-alcohol product can also be made by separating the must into a high-sugar fraction and low-sugar fraction prior to fermentation, blending additional must into the low-sugar fraction to form a mixture and then fermenting the mixture to form a low-alcohol red wine. The present invention permits the production of a low-alcohol wine without sacrificing the full body, aroma and character of traditional wine.