Abstract: Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.
Type:
Application
Filed:
March 18, 2015
Publication date:
September 17, 2015
Applicant:
Constellation Pharmaceuticals, Inc.
Inventors:
Brian K. Albrecht, James Edmund Audia, Andrew S. Cook, Les A. Dakin, Martin Duplessis, Victor S. Gehling, Jean-Christophe Harmange, Christopher G. Nasveschuk, Rishi G. Vaswani
Abstract: The present invention relates to compounds useful as inhibitors of bromodomain-containing proteins. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders.
Type:
Application
Filed:
June 6, 2013
Publication date:
May 28, 2015
Applicant:
CONSTELLATION PHARMACEUTICALS, INC.
Inventors:
Brian K. Albrecht, Michael Charles Hewitt, Victor S. Gehling, Rishi G. Vaswani
Abstract: The present invention relates to compounds useful as inhibitors of bromodomain-containing proteins. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders.
Type:
Application
Filed:
June 24, 2014
Publication date:
December 18, 2014
Applicant:
Constellation Pharmaceuticals, Inc.
Inventors:
Brian K. Albrecht, James Edmund Audia, Alexandre Côté, Victor S. Gehling, Jean-Christophe Harmange, Michael Charles Hewitt, Yves Leblanc, Christopher G. Nasveschuk, Alexander M. Taylor, Rishi G. Vaswani
Abstract: The present invention relates to compounds useful as inhibitors of bromodomain-containing proteins. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders.
Type:
Application
Filed:
June 15, 2012
Publication date:
October 2, 2014
Applicant:
CONSTELLATION PHARMACEUTICALS, INC.
Inventors:
Brian K. Albrecht, Jean-Christophe Harmange, Alexandre Cote, Alexander M. Taylor
Abstract: The present invention relates to compounds useful as inhibitors of one or more histone demethylses. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders.
Type:
Application
Filed:
March 13, 2014
Publication date:
September 18, 2014
Applicant:
Constellation Pharmaceuticals, Inc.
Inventors:
Brian K. Albrecht, Steven F. Bellon, Victor S. Gehling, Jean-Christophe Harmange
Abstract: The present invention relates to compounds useful as inhibitors of bromodomain-containing proteins. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders.
Type:
Grant
Filed:
December 2, 2011
Date of Patent:
August 5, 2014
Assignee:
Constellation Pharmaceuticals, Inc.
Inventors:
Brian K. Albrecht, James E. Audia, Alexandre Côté, Victor S. Gehling, Jean-Christophe Harmange, Michael C. Hewitt, Yves Leblanc, Christopher G. Nasveschuk, Alexander M. Taylor, Rishi G. Vaswani
Abstract: The present invention relates to compounds useful as inhibitors of bromodomain-containing proteins. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders.
Type:
Application
Filed:
May 4, 2012
Publication date:
May 15, 2014
Applicant:
CONSTELLATION PHARMACEUTICALS, INC.
Inventors:
Brian K. Albrecht, Victor S. Gehling, Michael C. Hewitt, Alexander M. Taylor, Jean-Christophe Harmange
Abstract: The present invention relates to compounds useful as inhibitors of bromodomain-containing proteins. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders.
Type:
Application
Filed:
December 2, 2011
Publication date:
June 21, 2012
Applicant:
CONSTELLATION PHARMACEUTICALS, INC.
Inventors:
Brian K. Albrecht, James E. Audia, Alexandre Côté, Victor S. Gehling, Jean-Christophe Harmange, Michael C. Hewitt, Yves LeBlanc, Christopher G. Naveschuk, Alexander M. Taylor, Rishi G. Vaswani