Abstract: Disclosed herein are new injection molding-coating devices for the continuous manufacturing of coated pharmaceutical tablets comprising one or more active pharmaceutical ingredients and one or more excipients. Also disclosed herein are methods for the continuous manufacture of coated pharmaceutical tablets using these new devices for the purpose application in the pharmaceutical and drug manufacturing industries.
Type:
Application
Filed:
June 10, 2019
Publication date:
September 21, 2023
Applicants:
Continuus Pharmaceuticals, Inc., I.M.A Industria Macchine Autommatiche S.p.A.
Inventors:
Bhakti HALKUDE, Federica CASATI, Evan James GOODWIN, Saptarshi CHATTOPADHYAY, Bayan Teisho TAKIZAWA, Salvatore MASCIA
Abstract: The present disclosure provides for a continuous rotary plate filter apparatus and a method of using the apparatus to separate slurries into liquids and solids. The methods and apparatus are useful for the production of fine chemicals and pharmaceuticals, particularly using Integrated Continuous Manufacturing (ICM), but can also be integrated with other manufacturing processes, such as batch and semi-continuous processes.
Type:
Grant
Filed:
February 3, 2017
Date of Patent:
May 24, 2022
Assignee:
Continuus Pharmaceuticals, Inc.
Inventors:
Stephen C. Born, Joshua Dittrich, Bayan T. Takizawa, Salvatore Mascia
Abstract: The present disclosure provides for a continuous membrane separator bypass system and a continuous filtration separator system and methods of using the systems in the separation of liquid-liquid mixtures and filtration of process liquids. The methods and apparatus are useful for the production of fine chemicals and pharmaceuticals, particularly using Integrated Continuous Manufacturing (ICM), but can also be integrated with other manufacturing processes, such as batch and semi-continuous processes.
Type:
Grant
Filed:
February 17, 2017
Date of Patent:
December 21, 2021
Assignee:
Continuus Pharmaceuticals, Inc.
Inventors:
Stephen C. Born, Ethan Disston Penner, Erica Marie Bortoff, Bayan T. Takizawa, Salvatore Mascia
Abstract: The present disclosure provides for a continuous membrane separator bypass system and a continuous filtration separator system and methods of using the systems in the separation of liquid-liquid mixtures and filtration of process liquids. The methods and apparatus are useful for the production of fine chemicals and pharmaceuticals, particularly using Integrated Continuous Manufacturing (ICM), but can also be integrated with other manufacturing processes, such as batch and semi-continuous processes.
Type:
Application
Filed:
February 17, 2017
Publication date:
December 10, 2020
Applicant:
Continuus Pharmaceuticals, Inc.
Inventors:
Stephen C. BORN, Ethan Disston PENNER, Erica Marie BORTOFF, Bayan T. TAKIZAWA, Salvatore MASCIA
Abstract: The present disclosure provides for a continuous rotary plate filter apparatus and a method of using the apparatus to separate slurries into liquids and solids. The methods and apparatus are useful for the production of fine chemicals and pharmaceuticals, particularly using Integrated Continuous Manufacturing (ICM), but can also be integrated with other manufacturing processes, such as batch and semi-continuous processes.
Type:
Application
Filed:
February 3, 2017
Publication date:
February 21, 2019
Applicant:
Continuus Pharmaceuticals, Inc.
Inventors:
Stephen C. BORN, Joshua DITTRICH, Bayan T. TAKIZAWA, Salvatore MASCIA
Abstract: The present disclosure provides for a continuous drying apparatus and a method of using the apparatus in the preparation of dried solids from slurries. The methods and apparatus are useful for the production of fine chemicals and pharmaceuticals, particularly using Integrated Continuous Manufacturing (ICM), but can also be integrated with other manufacturing processes, such as batch and semi-continuous processes.
Type:
Application
Filed:
February 3, 2017
Publication date:
February 14, 2019
Applicant:
Continuus Pharmaceuticals, Inc.
Inventors:
Stephen C. BORN, Joshua DITTRICH, Bayan T. TAKIZAWA, Salvatore MASCIA