Patents Assigned to CONVERGENE LLC
  • Small molecule BET bromodomain inhibitors and uses thereof
    Patent number: 11028079
    Abstract: The present invention relates to compounds that bind to and otherwise modulate the activity of bromodomain-containing proteins, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders.
    Type: Grant
    Filed: November 15, 2019
    Date of Patent: June 8, 2021
    Assignees: ConverGene, LLC, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Jeffrey William Strovel, Makoto Yoshioka, David J. Maloney, Shyh Yang, Ajit Jadhav, Daniel Jason Urban
  • Methods and compositions for inhibition of bromodomain-containing proteins
    Patent number: 10717739
    Abstract: The present invention relates to compounds that bind to and otherwise modulate the activity of bromodomain-containing proteins, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders.
    Type: Grant
    Filed: April 16, 2019
    Date of Patent: July 21, 2020
    Assignee: CONVERGENE LLC
    Inventors: Hariprasad Vankayalapati, Makoto Yoshioka, Jeffrey William Strovel, Janak Khimchand Padia
  • Bicyclic BET bromodomain inhibitors and uses thereof
    Patent number: 10508106
    Abstract: The present invention relates to compounds that bind to and otherwise modulate the activity of bromodomain-containing proteins, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders.
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: December 17, 2019
    Assignees: ConverGene LLC, The United States of America, As Represented by the Secretary, Department of Health and Human Services
    Inventors: Jeffrey William Strovel, Makoto Yoshioka, David J. Maloney, Shyh Ming Yang, Ajit Jadhav, Daniel Jason Urban
  • Methods and compositions for inhibition of bromodomain-containing proteins
    Patent number: 10266536
    Abstract: The present invention relates to compounds that bind to and otherwise modulate the activity of bromodomain-containing proteins, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders.
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: April 23, 2019
    Assignee: ConverGene LLC
    Inventors: Hariprasad Vankayalapati, Makoto Yoshioka, Jeffrey W. Strovel, Janak Khimchand Padia
  • Methods and compositions for inhibition of bromodomain-containing proteins
    Patent number: 9695179
    Abstract: The present invention relates to compounds that bind to and otherwise modulate the activity of bromodomain-containing proteins, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: July 4, 2017
    Assignee: ConverGene LLC
    Inventors: Hariprasad Vankayalapati, Makoto Yoshioka, Jeffrey William Strovel, Janak Khimchand Padia
  • METHODS AND COMPOSITIONS FOR INHIBITION OF BROMODOMAIN-CONTAINING PROTEINS
    Publication number: 20160024096
    Abstract: The present invention relates to compounds that bind to and otherwise modulate the activity of bromodomain-containing proteins, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders.
    Type: Application
    Filed: March 13, 2014
    Publication date: January 28, 2016
    Applicant: CONVERGENE LLC
    Inventors: Hariprasad Vankayalapati, Makoto Yoshioka, Jeffrey William Strovel, Janak Khimchand Padia