Patents Assigned to Cook Regentec LLC
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Patent number: 11173235Abstract: The present disclosure generally relates to implantable devices including a releasable nitrite ion and to methods of preparing and using such compositions and devices. In one embodiment, the device is a stent, for example, a vascular stent. In another embodiment, the nitrite ion is ionically bound to an inorganic ion.Type: GrantFiled: July 5, 2017Date of Patent: November 16, 2021Assignee: Cook Regentec LLCInventor: Chad E. Johnson
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Patent number: 10806891Abstract: A method for infusing a liquid into a patient's vasculature in accordance with an infusion protocol is disclosed. For this method, an infusion catheter having a multi-lumen infusion unit that is mounted adjacent the catheter's distal end is positioned in an artery within a predetermined distance from an intended target tissue surface. An inflation balloon is then deployed to at least partially occlude the artery and a force is exerted on the liquid to establish a flow rate for the liquid in the catheter. Specifically, the force is exerted to infuse the liquid from the catheter through the infusion unit and into the vasculature with a homogeneous distribution of the liquid to cover the intended surface of the target tissue. The flow rate can be established in accordance with an infusion protocol that is characterized by time and liquid volume parameters based on viscosity and pressure values in the liquid.Type: GrantFiled: October 30, 2018Date of Patent: October 20, 2020Assignee: Cook Regentec LLCInventors: Nabil Dib, Robert Edward Kohler
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Publication number: 20190269808Abstract: Disclosed are methods for treating platelet compositions (e.g. platelet concentrates and/or platelet lysates) with electron beam radiation, where the compositions are in a frozen state during irradiation with the e-beam radiation. The methods can be conducted using e-beam radiation at doses effective to reduce the pathogen content of the compositions while retaining highly beneficial bioactivities of the compositions. Also disclosed are compositions preparable by the methods, and methods and compositions involving the use of the e-beam treated materials.Type: ApplicationFiled: December 20, 2018Publication date: September 5, 2019Applicant: Cook Regentec LLCInventors: Steven Charlebois, Sreedhar Thirumala
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Publication number: 20190224239Abstract: The present disclosure provides a composition derived from a platelet concentrate, methods of making the composition, and culture medium supplemented with the composition. Preferred methods of making the composition include heat treating a platelet lysate composition.Type: ApplicationFiled: January 23, 2019Publication date: July 25, 2019Applicant: Cook Regentec LLCInventors: Jennifer Rodenberg, Eric Brandner, Hayley Steidinger, Amanda F. Taylor
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Patent number: 10155099Abstract: A method for infusing a liquid into a patient's vasculature in accordance with an infusion protocol is disclosed. For this method, an infusion catheter having a multi-lumen infusion unit that is mounted adjacent the catheter's distal end is positioned in an artery within a predetermined distance from an intended target tissue surface. An inflation balloon is then deployed to at least partially occlude the artery and a force is exerted on the liquid to establish a flow rate for the liquid in the catheter. Specifically, the force is exerted to infuse the liquid from the catheter through the infusion unit and into the vasculature with a homogeneous distribution of the liquid to cover the intended surface of the target tissue. The flow rate can be established in accordance with an infusion protocol that is characterized by time and liquid volume parameters based on viscosity and pressure values in the liquid.Type: GrantFiled: March 6, 2014Date of Patent: December 18, 2018Assignee: Cook Regentec LLCInventors: Nabil Dib, Robert Edward Kohler
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Patent number: 10058675Abstract: A system for moving particles suspended in a first fluid, and for infusing them into the stream of a second fluid, includes a catheter with a multi-lumen distal separator. The separator is formed with a plurality of parallel lumens, wherein each lumen has a predetermined diameter to reduce particle flocculation. An inflatable balloon, affixed to the outside of the catheter, can be provided to regulate flow of the second fluid and thereby facilitate entry of the particles into the stream of the second fluid. A reinforcing member is employed to strengthen the catheter wall under the inflatable balloon. With this arrangement, the catheter does not kink or collapse due to the pressure exerted on the catheter wall when the balloon is inflated. In one embodiment, the reinforcing member includes an annular shaped ring. In another embodiment, the separator is positioned under the balloon and acts as the reinforcing member.Type: GrantFiled: December 31, 2013Date of Patent: August 28, 2018Assignee: Cook Regentec LLCInventors: Nabil Dib, Robert Edward Kohler
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Patent number: 10039552Abstract: Magnetically actuated gating devices, magnetically actuated gating systems, magnetically actuated gating kits, and methods of treatment using a magnetically actuated gating device are described herein. An example embodiment of a magnetically actuated gating device comprises a housing, a rotatable member, a compression member, and a membrane. The rotatable member has a first magnetic field that is configured to interact with a second magnetic field produced by an external element to move the rotatable member between a first position and a second position.Type: GrantFiled: October 27, 2015Date of Patent: August 7, 2018Assignees: COOK MEDICAL TECHNOLOGIES LLC, COOK REGENTEC LLCInventors: Jarin Kratzberg, Keith Milner, Sara Sherman, Adam Shields
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Publication number: 20180015209Abstract: The present disclosure generally relates to implantable devices including a releasable nitrite ion and to methods of preparing and using such compositions and devices. In one embodiment, the device is a stent, for example, a vascular stent. In another embodiment, the nitrite ion is ionically bound to an inorganic ion.Type: ApplicationFiled: July 5, 2017Publication date: January 18, 2018Applicant: COOK REGENTEC LLCInventor: Chad E. Johnson
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Patent number: 9549715Abstract: Disclosed is a device useful for preserving tissue samples after extraction from human or animal patients. The device includes a circular blade for taking a tissue sample, the blade being coupled to a sealing cap which mates to one end of a container. A retrieval port is also disclosed for extracting fluids from the container. Methods are also disclosed by which tissue samples may be taken and prepared for storage, processing, culture, or other analysis.Type: GrantFiled: August 9, 2012Date of Patent: January 24, 2017Assignee: Cook Regentec LLCInventors: Erik J. Woods, Shelly J. Zacharias