Abstract: The present invention relates generally to novel recombinant polypeptides of Bahia grass pollen and to genetic sequences encoding same. More particularly, the present invention is directed to Pas n 1 polypeptides and derivatives, and fragments thereof and genetic sequences encoding same. The molecules of the present invention are useful in a range of therapeutic, prophylactic and diagnostic applications including, but not limited to, applications in the context of conditions characterised by an aberrant, inappropriate or otherwise unwanted immune response to the Bahia grass pollen.
Type:
Application
Filed:
October 21, 2008
Publication date:
January 20, 2011
Applicant:
COOPERATIVE RESEARCH CENTRE FOR ASTHMA
Inventors:
Robyn O'Hehir, Janet Davies, Jennifer Rolland
Abstract: The present invention relates generally to a method of prophylactically or therapeutically treating antigen-induced airway tissue inflammation and agents for use therein. More particularly, the present invention provides a method of prophylactically or therapeutically treating allergic airway inflammation and agents for use therein via the administration of the method of the present invention is useful, inter alia, in the treatment and/or prophylaxis of conditions characterised by antigen-induced airway tissue inflammation.
Type:
Application
Filed:
October 15, 2008
Publication date:
January 20, 2011
Applicant:
COOPERATIVE RESEARCH CENTRE FOR ASTHMA
Inventors:
Robyn Elizabeth O'Hehir, Magda Plebanski, Jennifer Rolland, Charles Linton Hardy