Abstract: Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
Type:
Application
Filed:
September 13, 2005
Publication date:
March 30, 2006
Applicant:
Corixa Corpoation
Inventors:
Raymond Houghton, Paul Sleath, David Persing