Abstract: Calcium-phosphate nanofiber matrices comprising randomly dispersed crystalline calcium-phosphate nanofibers are provided. The nanofibers are synthesized using sol-gel methods combined with electrospinning. The nanofibers may be hollow, solid or may comprise a calcium-phosphate shell surrounding a polymer containing inner core to which biologically functional additives may be added. The nanofiber matrices may be used to culture bone and dental cells, and as implants to treat bone, dental or periodontal diseases and defects.
Abstract: A composite of a polyester, e.g., a polycarbonate, and a nanoclay (layered silicate) cation exchanged with a quaternized copolymer of styrene and 2-(dimethylamine) ethyl methacrylate is provided, the composite being useful for preparing injection molded objects and after injection molding being transparent and without coloration and has enhanced modulus and strength compared to neat polyester and does not have loss of elongation and toughness compared to neat polyester.
Type:
Grant
Filed:
December 19, 2003
Date of Patent:
December 12, 2006
Assignee:
Cornell Research Foundations, Inc.
Inventors:
Emmanuel P. Giannelis, Jin Zhu, Byoungkyeu Park, Kyung Hoon Seo