Abstract: A diagnostic assay strip includes a first layer that includes an iron mobile labelled specific binding partner that will bind to and iron biomarker from a sample and produce an iron complex and a vitamin A mobile labelled specific binding partner that will bind to a vitamin A biomarker from the sample and produce a vitamin A complex. A second layer includes iron and vitamin A test regions, and a control region. The iron test region has immobilized specific binding partners that will bind to the iron complex. The vitamin A test region has immobilized vitamin A biomarker that will bind to vitamin A mobile labelled specific binding partner, which is not bound to the vitamin A biomarker, passing from the first layer to the second layer. The control region has a moiety which will non-specifically bind to and immobilize the iron and vitamin A labelled specific binding partners. Methods of using the diagnostic assay strip are also discussed.
Type:
Grant
Filed:
November 13, 2018
Date of Patent:
June 6, 2023
Assignee:
CORNELL UNIVERISTY
Inventors:
Saurabh Mehta, David Erickson, Zhengda Lu
Abstract: The present invention relates to carbon-based fluorescent nano-agent tracers for analysis of oil reservoirs. The carbon-based fluorescent nano-agents may be used in the analysis of the porosity of a formation. The nanoagents are suitable for injection into a petroleum reservoir and may be recovered from the reservoir for the determination of hydrocarbon flow rates and retention times.
Type:
Grant
Filed:
February 20, 2015
Date of Patent:
November 15, 2016
Assignees:
Saudi Arabian Oil Company, Cornell Univeristy
Inventors:
Mazen Y. Kanj, Mohammad Harunar Rashid, Emmanuel Giannelis
Abstract: A method and system for automatically summarizing fine-grained opinions in digital text are disclosed. Accordingly, a digital text is analyzed for the purpose of extracting all opinion expressions found in the text. Next, the extracted opinion expressions (referred to herein as opinion frames) are analyzed to generate opinion summaries. In forming an opinion summary, those opinion frames sharing in common an opinion source and/or opinion topic may be combined, such that an overall opinion summary indicates an aggregate opinion held by the common source toward the common topic.
Type:
Grant
Filed:
September 27, 2012
Date of Patent:
July 28, 2015
Assignee:
Cornell Univeristy, Cornell Center for Technology, Enterprise & Commercialization
Inventors:
Claire Cardie, Vaselin Stoyanov, Eric Breck, Yejin Choi
Abstract: Multiplexed electrospray deposition apparatus capable of delivering picoliter volumes of one or more substances is disclosed. The apparatus may include a unitary planar dispenser etched from a silicon wafer through microfabrication or micromachining technology. The apparatus may be used as a deposition tool for making protein microarrays in a noncontact mode. Upon application of potential difference in the range of 7-9 kV, the substances may be dispensed directly, not through a collimating mask, onto a substrate with microhydrogel features functionalized with an anchoring agent.
Abstract: Described herein are new enone derivatives and conjugates. Additionally, methods for synthesizing these new enones are also disclosed. These compounds can be employed in cancer therapy.
Type:
Grant
Filed:
December 7, 2004
Date of Patent:
August 4, 2009
Assignee:
Cornell Univeristy
Inventors:
Bruce Ganem, Donald J. Creighton, Diana S. Hamilton, Zhebo Ding