Patents Assigned to Cornerstone Pharmaceuticals
  • Therapeutic methods and compositions for treating pancreatic cancer using 6,8-bis-benzylthio-octanoic acid
    Patent number: 11622950
    Abstract: The invention provides methods, compositions, and medical kits for treating pancreatic cancer using (i) 6,8-bis(benzylsulfanyl)octanoic acid or a pharmaceutically acceptable salt thereof in combination with (ii) gemcitabine or a pharmaceutically acceptable salt thereof, and (iii) nab-paclitaxel.
    Type: Grant
    Filed: July 23, 2019
    Date of Patent: April 11, 2023
    Assignee: Cornerstone Pharmaceuticals, Inc.
    Inventors: Sanjeev Luther, Robert G. L. Shorr
  • Methods of treating colon, lung, and liver cancers using compositions containing an ion pair of a lipoic acid derivative
    Patent number: 9320726
    Abstract: The invention provides a method of treating colon, lung, and liver cancers using a pharmaceutical composition containing a pharmaceutically acceptable diluent along with an ion pair formed by triethanolamine and a compound of Formula I:
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: April 26, 2016
    Assignee: Cornerstone Pharmaceuticals, Inc.
    Inventors: Robert G. L. Shorr, Robert J. Rodriguez, Rajinder Bhasin
  • PHARMACEUTICAL COMPOUNDS
    Publication number: 20150322103
    Abstract: Therapeutically-effective amounts of novel analogs or derivatives of alkyl fatty, acids, such as but not limited to lipoic acid, and pharmaceutical formulations comprising such analogs or derivatives and pharmaceutically-acceptable carriers therefor, are useful for the treatment, prevention, imaging, and/or diagnosis of medical disorders.
    Type: Application
    Filed: December 19, 2013
    Publication date: November 12, 2015
    Applicant: CORNERSTONE PHARMACEUTICALS, INC.
    Inventors: Robert Shorr, Robert Rodriguez, Paul Bingham, Lakmal Boteju, Thomas Kwok, James Marecek
  • Lipoic acid derivatives
    Patent number: 9150509
    Abstract: Lipoic acid derivatives and pharmaceutical formulations containing lipoic acid derivatives are useful in the treatment and prevention of disease characterized by disease cells that are sensitive to lipoic acid derivatives.
    Type: Grant
    Filed: June 25, 2014
    Date of Patent: October 6, 2015
    Assignee: Cornerstone Pharmaceuticals, Inc.
    Inventors: Paul Bingham, Tom Kwok, Zuzana Zachar
  • PHARMACEUTICAL FORMULATIONS CONTAINING LIPOIC ACID DERIVATIVES
    Publication number: 20150011633
    Abstract: Pharmaceutical formulations containing lipoic acid derivatives are made.
    Type: Application
    Filed: March 27, 2014
    Publication date: January 8, 2015
    Applicant: Cornerstone Pharmaceuticals, Inc.
    Inventors: Robert G. L. Shorr, Robert J. Rodriguez, Rajinder Bhasin
  • Lipoic acid derivatives
    Patent number: 8785475
    Abstract: Lipoic acid derivatives and pharmaceutical formulations containing lipoic acid derivatives are useful in the treatment and prevention of disease characterized by disease cells that are sensitive to lipoic acid derivatives.
    Type: Grant
    Filed: April 17, 2008
    Date of Patent: July 22, 2014
    Assignee: Cornerstone Pharmaceuticals, Inc.
    Inventors: Paul Bingham, Tom Kwok, Zuzana Zachar
  • Pharmaceutical formulations containing lipoic acid derivatives
    Patent number: 8691873
    Abstract: The invention provides a method of treating leukemia using a pharmaceutical composition containing bis-benzyl lipoate, triethanolamine, and a pharmaceutically acceptable diluent, where the bis-benzyl lipoate and triethanolamine form an ion pair.
    Type: Grant
    Filed: October 5, 2011
    Date of Patent: April 8, 2014
    Assignee: Cornerstone Pharmaceuticals, Inc.
    Inventors: Robert G. L. Shorr, Robert J. Rodriguez, Rajinder Bhasin
  • Pharmaceutical formulations containing lipoic acid derivatives
    Patent number: 8263653
    Abstract: The invention provides ion pairs of a lipoic acid derivative and an ion pairing agent, pharmaceutical formulations containing such ion pairs, and methods of using the ion pairs and pharmaceutical formulations in the treatment of medical disorders, such as cancer. An exemplary ion pair is the ion pair formed by bis-benzyl lipoate and triethanolamine. The pharmaceutical formulations may comprise a dextrose solution as a diluent.
    Type: Grant
    Filed: October 23, 2009
    Date of Patent: September 11, 2012
    Assignee: Cornerstone Pharmaceuticals, Inc.
    Inventors: Robert G. L. Shorr, Robert J. Rodriguez, Rajinder Bhasin
  • Pharmaceutical and diagnostic compositions containing nanoparticles useful for treating targeted tissues and cells
    Patent number: 7521066
    Abstract: Nanoparticles made from a select group of lipids and optionally containing a therapeutically active agent are employed in pharmaceutical compositions for delivery to targeted tissues and/or cells for the treatment or diagnosis of such diseases as cancer.
    Type: Grant
    Filed: April 30, 2007
    Date of Patent: April 21, 2009
    Assignee: Cornerstone Pharmaceuticals
    Inventors: Robert Shorr, Robert Rodriguez
  • Pharmaceutical and diagnostic compositions containing nanoparticles useful for treating targeted tissues and cells
    Patent number: 7387790
    Abstract: Nanoparticles made from a select group of lipids and optionally containing a therapeutically active agent are employed in pharmaceutical compositions for delivery to targeted tissues and/or cells for the treatment or diagnosis of such diseases as cancer.
    Type: Grant
    Filed: June 14, 2002
    Date of Patent: June 17, 2008
    Assignee: Cornerstone Pharmaceuticals
    Inventors: Robert Shorr, Robert Rodriguez
  • Pharmaceutical and diagnostic compositions containing nanoparticles useful for treating targeted tissues and cells
    Patent number: 7220428
    Abstract: Nanoparticles made from a select group of lipids and optionally containing a therapeutically active agent are employed in pharmaceutical compositions for delivery to targeted tissues and/or cells for the treatment or diagnosis of such diseases as cancer.
    Type: Grant
    Filed: October 27, 2004
    Date of Patent: May 22, 2007
    Assignee: Cornerstone Pharmaceuticals
    Inventors: Robert Shorr, Robert Rodriguez
  • Pharmaceutical and diagnostic compositions containing nanoparticles useful for treating targeted tissues and cells
    Patent number: RE43295
    Abstract: Nanoparticles made from a select group of lipids and optionally containing a therapeutically active agent are employed in pharmaceutical compositions for delivery to targeted tissues and/or cells for the treatment or diagnosis of such diseases as cancer.
    Type: Grant
    Filed: April 20, 2011
    Date of Patent: April 3, 2012
    Assignee: Cornerstone Pharmaceuticals, Inc.
    Inventors: Robert G. L. Shorr, Robert J. Rodriguez