Abstract: The present invention provides cyclic nitro compound, pharmaceutical compositions of cyclic nitro compounds and methods of using cyclic nitro compounds and/or pharmaceutical compositions thereof to treat or prevent diseases or disorders characterized by abnormal cell proliferation, such as cancer, inflammation, cardiovascular disease and autoimmune disease.
Type:
Grant
Filed:
February 26, 2021
Date of Patent:
March 12, 2024
Assignees:
NORTHROP GRUMMAN SYSTEMS, CORPORATION and EPICENTRX, INC.
Inventors:
Mark D. Bednarski, Susan Knox, Louis Cannizzo, Kirstin Warner, Robert Wardle, Stephen Velarde, Shoucheng Ning