Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.
Type:
Application
Filed:
September 13, 2019
Publication date:
February 27, 2020
Applicant:
CORSAIR PHARMA, INC.
Inventors:
Cyrus K. BECKER, Meenakshi S. VENKATRAMAN, Xiaoming ZHANG
Abstract: The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
Type:
Grant
Filed:
July 19, 2018
Date of Patent:
November 5, 2019
Assignee:
Corsair Pharma, Inc.
Inventors:
Xiaoming Zhang, Meenakshi S. Venkatraman, Cyrus K. Becker
Abstract: The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
Type:
Grant
Filed:
March 21, 2018
Date of Patent:
November 5, 2019
Assignee:
Corsair Pharma, Inc.
Inventors:
Xiaoming Zhang, Meenakshi S. Venkatraman, Cyrus K. Becker
Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.
Type:
Grant
Filed:
November 13, 2017
Date of Patent:
October 22, 2019
Assignee:
Corsair Pharma, Inc.
Inventors:
Cyrus K. Becker, Meenakshi S. Venkatraman, Xiaoming Zhang
Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.
Type:
Grant
Filed:
August 25, 2017
Date of Patent:
July 9, 2019
Assignee:
Corsair Pharma, Inc.
Inventors:
Cyrus K. Becker, Meenakshi S. Venkatraman, Xiaoming Zhang, Jürg Pfister
Abstract: The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
Type:
Grant
Filed:
June 14, 2016
Date of Patent:
April 2, 2019
Assignee:
CORSAIR PHARMA, INC.
Inventors:
Xiaoming Zhang, Meenakshi S. Venkatraman, Cyrus K. Becker
Abstract: The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
Type:
Grant
Filed:
June 8, 2017
Date of Patent:
August 21, 2018
Assignee:
CORSAIR PHARMA, INC.
Inventors:
Xiaoming Zhang, Meenakshi S. Venkatraman, Cyrus K. Becker
Abstract: The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
Type:
Grant
Filed:
March 29, 2017
Date of Patent:
May 1, 2018
Assignee:
CORSAIR PHARMA, INC.
Inventors:
Xiaoming Zhang, Meenakshi S. Venkatraman, Cyrus K. Becker
Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable dosage. Transdermal applications can be used.
Type:
Grant
Filed:
October 18, 2016
Date of Patent:
December 19, 2017
Assignee:
CORSAIR PHARMA, INC.
Inventors:
Cyrus K. Becker, Jürg R. Pfister, Gwenaella Rescourio, Meenakshi S. Venkatraman, Xiaoming Zhang
Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.
Type:
Grant
Filed:
May 18, 2016
Date of Patent:
October 3, 2017
Assignee:
CORSAIR PHARMA, INC.
Inventors:
Cyrus K. Becker, Meenakshi S. Venkatraman, Xiaoming Zhang
Abstract: The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
Type:
Grant
Filed:
June 10, 2016
Date of Patent:
July 11, 2017
Assignee:
CORSAIR PHARMA, INC.
Inventors:
Xiaoming Zhang, Meenakshi S. Venkatraman, Cyrus K. Becker
Abstract: The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
Type:
Grant
Filed:
August 18, 2015
Date of Patent:
May 9, 2017
Assignee:
CORSAIR PHARMA, INC.
Inventors:
Xiaoming Zhang, Meenakshi S. Venkatraman, Cyrus K. Becker
Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.
Type:
Grant
Filed:
July 16, 2014
Date of Patent:
November 29, 2016
Assignee:
CORSAIR PHARMA, INC.
Inventors:
Cyrus K. Becker, Jürg R. Pfister, Gwenaella Rescourio, Meenakshi S. Venkatraman, Xiaoming Zhang
Abstract: The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
Type:
Grant
Filed:
June 17, 2015
Date of Patent:
July 19, 2016
Assignee:
CORSAIR PHARMA, INC.
Inventors:
Xiaoming Zhang, Meenakshi S. Venkatraman, Cyrus K. Becker
Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.
Type:
Grant
Filed:
January 13, 2014
Date of Patent:
June 21, 2016
Assignee:
CORSAIR PHARMA, INC.
Inventors:
Cyrus K. Becker, Jürg R. Pfister, Gwenaella Rescourio, Meenakshi S. Venkatraman, Xiaoming Zhang
Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.
Type:
Application
Filed:
January 13, 2014
Publication date:
September 11, 2014
Applicant:
Corsair Pharma, Inc.
Inventors:
Cyrus K. BECKER, Jürg R. PFISTER, Gwenaella RESCOURIO, Meenakshi S. VENKATRAMAN, Xiaoming ZHANG