Patents Assigned to Cortendo AB

Method for treating insulin resistance, abdominal obesity, hypertension, hyperinsulinemia, and elevated blood lipids with a cortisol inhibitor

Patent number: 7960410

Abstract: The invention concerns the use of ketoconazole and derivatives having a corresponding biological activity, and combinations thereof, in the treatment of abdominal obesity, hypertension, hyperinsulinemia, and elevated blood lipids.

Type: Grant

Filed: September 10, 2005

Date of Patent: June 14, 2011

Assignee: Cortendo AB

Inventor: Per Marin
Method for treating insulin resistance, abdominal obesity, hypertension, hyperinsulinemia, and elevated blood lipids with a cortisol inhibitor

Patent number: 7872008

Abstract: The invention concerns the use of ketoconazole and derivatives having a corresponding biological activity, and combinations thereof, in the treatment of abdominal obesity, hypertension, hyperinsulinemia, and elevated blood lipids.

Type: Grant

Filed: September 4, 2003

Date of Patent: January 18, 2011

Assignee: Cortendo AB

Inventor: Per Marin
Method for determining whether condition is symptom of metabolic syndrome

Patent number: 7217505

Abstract: The use of cortisol agonist for preparing a system for diagnosis of the metabolic syndrome and related conditions as belly fatness, insulin resistancy including increased risk of developing senile diabetes, i.e. diabetes type II, high blood fats and high blood pressure, in which system the dose of cortisol agonist is in an interval where a difference is obtained in the inhibitory effect of the autoproduction of cortisol in individuals suffering from the metabolic syndrome, compared to normal values.

Type: Grant

Filed: June 25, 2002

Date of Patent: May 15, 2007

Assignee: Cortendo AB

Inventor: Per Marin
Methods for prophylactic treatment of cardiovascular disease with inhibitor of cortisol synthesis

Patent number: 6642236

Abstract: Ketoconazole and related substances which are inhibitors of cortisol synthesis can be administered to prophylactically treat cardiovascular disease, such as coronary artery disease, artiosclerotic manifestations, and stroke.

Type: Grant

Filed: November 14, 2000

Date of Patent: November 4, 2003

Assignee: Cortendo AB

Inventor: Per Märin
Preparation for the treatment of metabolic syndrome containing human growth hormone in combination with a cortisol synthesis inhibitor

Patent number: 6274582

Abstract: Human growth hormone is used in combination with a cortisol synthesis inhibitor, in particular ketoconazole, for prevention or treatment of conditions related to Metabolis Syndrome (Neuroendocrine Syndrome). Administration can be supplemented by a sex hormone selected from testosterone and natural or synthetic estrogen. Also disclosed are corresponding pharmaceutical compositions.

Type: Grant

Filed: August 24, 1999

Date of Patent: August 14, 2001

Assignee: Cortendo AB

Inventor: Per Mårin
Methods for using ketoconazole and related substances in medicaments for treatment of type II diabetes

Patent number: 5849740

Abstract: The present invention is a method of using ketoconazole or molecules resembling ketoconazole with comparable biological activity for the manufacture of drugs and for medical treatment of diabetes mellitus type II as well as for counteracting the other risk factors associated with the Metabolic Syndrome.

Type: Grant

Filed: February 6, 1997

Date of Patent: December 15, 1998

Assignee: Cortendo AB

Inventor: Per Marin

Method for treating insulin resistance, abdominal obesity, hypertension, hyperinsulinemia, and elevated blood lipids with a cortisol inhibitor

Method for treating insulin resistance, abdominal obesity, hypertension, hyperinsulinemia, and elevated blood lipids with a cortisol inhibitor

Method for determining whether condition is symptom of metabolic syndrome

Methods for prophylactic treatment of cardiovascular disease with inhibitor of cortisol synthesis

Preparation for the treatment of metabolic syndrome containing human growth hormone in combination with a cortisol synthesis inhibitor

Methods for using ketoconazole and related substances in medicaments for treatment of type II diabetes